Search Results - "Munn, Paul R."
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Parallel evolution of ancient, pleiotropic enhancers underlies butterfly wing pattern mimicry
Published in Proceedings of the National Academy of Sciences - PNAS (26-11-2019)“…Color pattern mimicry in Heliconius butterflies is a classic case study of complex trait adaptation via selection on a few large effect genes. Association…”
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Multiple stages of evolutionary change in anthrax toxin receptor expression in humans
Published in Nature communications (15-11-2021)“…The advent of animal husbandry and hunting increased human exposure to zoonotic pathogens. To understand how a zoonotic disease may have influenced human…”
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Chromatin conformation remains stable upon extensive transcriptional changes driven by heat shock
Published in Proceedings of the National Academy of Sciences - PNAS (24-09-2019)“…Heat shock (HS) initiates rapid, extensive, and evolutionarily conserved changes in transcription that are accompanied by chromatin decondensation and…”
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Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation
Published in Cell reports. Medicine (16-01-2024)“…Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious and poorly understood disease. To understand immune dysregulation in ME/CFS, we use…”
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Chemical, Molecular, and Single-nucleus Analysis Reveal Chondroitin Sulfate Proteoglycan Aberrancy in Fibrolamellar Carcinoma
Published in Cancer research communications (01-07-2022)“…Fibrolamellar carcinoma (FLC) is an aggressive liver cancer with no effective therapeutic options. The extracellular environment of FLC tumors is poorly…”
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Abstract 1460: Decoding the tumor biology of the orphan malignancy fibrolamellar carcinoma at single-cell resolution
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract The World Health Organization (WHO) recognized fibrolamellar carcinoma (FLC) in 2010 as a rare and aggressive form of liver cancer that predominately…”
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