Search Results - "Munkuev, Aldar A."

Novel Tdp1 Inhibitors Based on Adamantane Connected with Monoterpene Moieties via Heterocyclic Fragments by Munkuev, Aldar A., Mozhaitsev, Evgenii S., Chepanova, Arina A., Suslov, Evgeniy V., Korchagina, Dina V., Zakharova, Olga D., Ilina, Ekaterina S., Dyrkheeva, Nadezhda S., Zakharenko, Alexandra L., Reynisson, Jóhannes, Volcho, Konstantin P., Salakhutdinov, Nariman F., Lavrik, Olga I.

“…Tyrosyl-DNA phosphodiesterase 1 (Tdp1) is a promising target for anticancer therapy due to its ability to counter the effects topoisomerase 1 (Top1) poison,…”
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Novel Bispidine-Monoterpene Conjugates-Synthesis and Application as Ligands for the Catalytic Ethylation of Chalcones by Suslov, Evgeniy V, Ponomarev, Konstantin Y, Patrusheva, Oxana S, Kuranov, Sergey O, Okhina, Alina A, Rogachev, Artem D, Munkuev, Aldar A, Ottenbacher, Roman V, Dalinger, Alexander I, Kalinin, Mikhail A, Vatsadze, Sergey Z, Volcho, Konstantin P, Salakhutdinov, Nariman F

“…A number of new chiral bispidines containing monoterpenoid fragments have been obtained. The bispidines were studied as ligands for Ni-catalyzed addition of…”
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Adamantane-Monoterpenoid Conjugates Linked via Heterocyclic Linkers Enhance the Cytotoxic Effect of Topotecan by Munkuev, Aldar A, Dyrkheeva, Nadezhda S, Kornienko, Tatyana E, Ilina, Ekaterina S, Ivankin, Dmitry I, Suslov, Evgeniy V, Korchagina, Dina V, Gatilov, Yuriy V, Zakharenko, Alexandra L, Malakhova, Anastasia A, Reynisson, Jóhannes, Volcho, Konstantin P, Salakhutdinov, Nariman F, Lavrik, Olga I

“…Inhibiting tyrosyl-DNA phosphodiesterase 1 (TDP1) is a promising strategy for increasing the effectiveness of existing antitumor therapy since it can remove…”
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The Development of Tyrosyl-DNA Phosphodiesterase 1 Inhibitors. Combination of Monoterpene and Adamantine Moieties via Amide or Thioamide Bridges by Chepanova, Arina A., Mozhaitsev, Evgenii S., Munkuev, Aldar A., Suslov, Evgeniy V., Korchagina, Dina V., Zakharova, Olga D., Zakharenko, Alexandra L., Patel, Jinal, Ayine-Tora, Daniel M., Reynisson, Jóhannes, Leung, Ivanhoe K. H., Volcho, Konstantin P., Salakhutdinov, Nariman F., Lavrik, Olga I.

“…Eleven amide and thioamide derivatives with monoterpene and adamantine substituents were synthesised. They were tested for their activity against the…”
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Synthesis of adamantane-monoterpene conjugates with 1,3,4-thiadiazol-2(3H)-imine linker and evaluation of their inhibitory activity against TDP1 by Munkuev, Aldar A., Zakharenko, Alexandra L., Kornienko, Tatyana E., Dyrkheeva, Nadezhda S., Ilina, Ekaterina S., Suslov, Evgeniy V., Issa, Fatima, Achara, Chigozie, Reynisson, Jóhannes, Volcho, Konstantin P., Salakhutdinov, Nariman F., Lavrik, Olga I.

“…Tyrosyl-DNA phosphodiesterase 1 (TDP1) is a DNA repair enzyme that can reduce the efficacy of some anticancer drugs targeting topoisomerase 1 (TOP1) making it…”
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