Search Results - "Munjoma, Nyasha C."
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Detection of pharmacolipidodynamic effects following the intravenous and oral administration of gefitinib to C57Bl/6JRj mice by rapid UHPLC-MS analysis of plasma
Published in Scientific reports (24-07-2024)“…Omics-based biomarker technologies, including metabolic profiling (metabolomics/metabonomics) and lipidomics, are making a significant impact on disease…”
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Development of a single mobile phase for LC-IM-MS-based discovery lipidomics and metabolic phenotyping: Application to methapyrilene hepatotoxicity in the rat
Published in Journal of Chromatography A (11-01-2024)“…•A generic mobile phase has been developed for metabolomic and lipidomic separations•Isopropyl alcohol was replaced by acetonitrile as the organic modifier for…”
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A comparison of collision cross section values obtained via travelling wave ion mobility-mass spectrometry and ultra high performance liquid chromatography-ion mobility-mass spectrometry: Application to the characterisation of metabolites in rat urine
Published in Journal of Chromatography A (27-09-2019)“…•CCS data were obtained for over 500 metabolites by direct infusion at two sites.•Excellent agreement was seen for the CCS data generated at both sites.•Good…”
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Metabolic Phenotyping Using UPLC–MS and Rapid Microbore UPLC–IM–MS: Determination of the Effect of Different Dietary Regimes on the Urinary Metabolome of the Rat
Published in Chromatographia (01-07-2020)“…A rapid reversed-phase gradient method employing a 50 mm × 1 mm i.d., C18 microbore column, combined with ion mobility and high-resolution mass spectrometry,…”
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