Search Results - "Muniz, Debora Feitosa"
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Effect of estragole over the RN4220 Staphylococcus aureus strain and its toxicity in Drosophila melanogaster
Published in Life sciences (1973) (01-01-2021)“…Among the bacterial resistance mechanisms, efflux pumps are responsible for expelling xenobiotics, including bacterial cell antibiotics. Given this problem,…”
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In Vitro and In Silico Inhibition of Staphylococcus aureus Efflux Pump NorA by α-Pinene and Limonene
Published in Current microbiology (01-09-2021)“…Since the discovery of the first antibiotics, bacteria have acquired a variety of resistance mechanisms, with efflux pump (EP) being the most prominent…”
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GC-MS-FID and potentiation of the antibiotic activity of the essential oil of Baccharis reticulata (ruiz & pav.) pers. and α-pinene
Published in Industrial crops and products (01-03-2020)“…•The essential oil of B. reticulata inhibited the multiresistant strain of S. aureus;•This essential oil enhanced the antibiotic activity of norfloxacin and…”
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Evaluation of isoeugenol in inhibition of Staphylococcus aureus efflux pumps and their toxicity using Drosophila melanogaster model
Published in Life sciences (1973) (15-11-2021)“…The Staphylococcus aureus bacteria is a pathogen considered opportunistic and that has been acquiring resistance to several classes of antibiotics, mainly due…”
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NorA, Tet(K), MepA, and MsrA Efflux Pumps in Staphylococcus aureus , their Inhibitors and 1,8-Naphthyridine Sulfonamides
Published in Current pharmaceutical design (01-01-2023)“…Antibiotic resistance can be characterized, in biochemical terms, as an antibiotic's inability to reach its bacterial target at a concentration that was…”
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Evaluation of the Antibacterial Activity and Efflux Pump Reversal of Thymol and Carvacrol against Staphylococcus aureus and Their Toxicity in Drosophila melanogaster
Published in Molecules (Basel, Switzerland) (30-04-2020)“…The antibacterial activity and efflux pump reversal of thymol and carvacrol were investigated against the IS-58 strain in this study, as well as their toxicity…”
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Evaluation of Elaiophylin extracted from Streptomyces hygroscopicus as a potential inhibitor of the NorA efflux protein in Staphylococcus aureus: An in vitro and in silico approach
Published in Bioorganic & medicinal chemistry letters (15-10-2021)“…[Display omitted] Compounds capable of inhibiting the efflux pump mechanism are a promising alternative against bacterial resistance because, when combined…”
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Use of Flavonoids and Cinnamates, the Main Photoprotectors with Natural Origin
Published in Advances in Pharmacological Sciences (01-01-2018)“…Many pathological problems are initiated by ultraviolet radiation (UVR), such as skin cancer, the most commonly diagnosed cancer worldwide. The UVA (320–400…”
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The 1,8-naphthyridines sulfonamides are NorA efflux pump inhibitors
Published in Journal of global antimicrobial resistance. (01-03-2021)“…•1,8-naphthyridine sulfonamides showed synergy with norfloxacin and ethidium bromide.•MICs of multidrug-resistant S. aureus strains SA-1199 and SA-1199B were…”
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Chemical Profile, Antibacterial Activity and Antibiotic-Modulating Effect of the Hexanic Zea Mays L. Silk Extract (Poaceae)
Published in Antibiotics (Basel) (12-03-2019)“…The present study aimed to determine the chemical profile and to evaluate the antibacterial activity and antibiotic-modulating action of the hexanic silk…”
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In vitro and in silico inhibitory effects of synthetic and natural eugenol derivatives against the NorA efflux pump in Staphylococcus aureus
Published in Food chemistry (01-02-2021)“…•Compounds with the most functional groups obtained clinically relevant results.•Against SA 1199B only isoeugenol had direct antibacterial activity.•For the…”
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GC-MS-FID characterization and antibacterial activity of the Mikania cordifolia essential oil and limonene against MDR strains
Published in Food and chemical toxicology (01-02-2020)“…The present study evaluated the effect of the essential oil of Mikania cordifolia (EOMc) and its major constituent limonene alone or associated with…”
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Evaluation of the antibacterial and inhibitory activity of the MepA efflux pump of Staphylococcus aureus by riparins I, II, III, and IV
Published in Archives of biochemistry and biophysics (15-10-2023)“…The efflux pump mechanism contributes to the antibiotic resistance of widely distributed strains of Staphylococcus aureus. Therefore, in the present work, the…”
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Chemical synthesis, molecular docking and MepA efflux pump inhibitory effect by 1,8-naphthyridines sulfonamides
Published in European journal of pharmaceutical sciences (01-05-2021)“…This study aimed to evaluate the antibacterial activity and to verify, in silico and in vitro, the inhibition of efflux mechanisms using a series of…”
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Inhibition of the MepA efflux pump by limonene demonstrated by in vitro and in silico methods
Published in Folia microbiologica (01-02-2022)“…Bacterial resistance is a natural process carried out by bacteria, which has been considered a public health problem in recent decades. This process can be…”
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Do 1,8-naphthyridine sulfonamides possess an inhibitory action against Tet(K) and MsrA efflux pumps in multiresistant Staphylococcus aureus strains?
Published in Microbial pathogenesis (01-10-2020)“…Naphthyridines represent a class of heterocyclic compounds formed by two condensed aromatic rings. This study aimed to evaluate the antibacterial activity and…”
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Antibacterial activity of eugenol on the IS-58 strain of Staphylococcus aureus resistant to tetracycline and toxicity in Drosophila melanogaster
Published in Microbial pathogenesis (01-03-2022)“…The indiscriminate use of antibiotics contributes significantly to the selection of bacteria resistant to several antibiotics. Among the resistance mechanisms…”
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Characterization and antibacterial activity of the essential oil obtained from the leaves of Baccharis coridifolia DC against multiresistant strains
Published in Microbial pathogenesis (01-08-2020)“…Essential oils are secondary metabolites with immense pharmacological potential.These substances are abundantly produced by plants of the family Asteraceae,…”
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Phytochemical analysis, antibacterial activity and antibiotic modifying action of Jatropha mollissima (Pohl.) Baill. (Euphorbiaceae)
Published in Anales de biología (01-12-2020)“…La aparición de cepas bacterianas resistentes y los efectos secundarios de sus fármacos disponibles han hecho investigar nuevos compuestos antibacterianos…”
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