Search Results - "Mungo, Eleonora"

ERK is a Pivotal Player of Chemo-Immune-Resistance in Cancer by Salaroglio, Iris C, Mungo, Eleonora, Gazzano, Elena, Kopecka, Joanna, Riganti, Chiara

“…The extracellular signal-related kinases (ERKs) act as pleiotropic molecules in tumors, where they activate pro-survival pathways leading to cell proliferation…”
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Mitochondria-Targeted Doxorubicin: A New Therapeutic Strategy against Doxorubicin-Resistant Osteosarcoma by Buondonno, Ilaria, Gazzano, Elena, Jean, Sae Rin, Audrito, Valentina, Kopecka, Joanna, Fanelli, Marilù, Salaroglio, Iris C, Costamagna, Costanzo, Roato, Ilaria, Mungo, Eleonora, Hattinger, Claudia M, Deaglio, Silvia, Kelley, Shana O, Serra, Massimo, Riganti, Chiara

“…Doxorubicin is one of the leading drugs for osteosarcoma standard chemotherapy. A total of 40% to 45% of high-grade osteosarcoma patients are unresponsive, or…”
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Knock-Out of IKKepsilon Ameliorates Atherosclerosis and Fatty Liver Disease by Alterations of Lipid Metabolism in the PCSK9 Model in Mice by Weiss, Ulrike, Mungo, Eleonora, Haß, Michelle, Benning, Denis, Gurke, Robert, Hahnefeld, Lisa, Dorochow, Erika, Schlaudraff, Jessica, Schmid, Tobias, Kuntschar, Silvia, Meyer, Sofie, Medert, Rebekka, Freichel, Marc, Geisslinger, Gerd, Niederberger, Ellen

“…The inhibitor-kappaB kinase epsilon (IKKε) represents a non-canonical IκB kinase that modulates NF-κB activity and interferon I responses. Inhibition of this…”
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Pyruvate Treatment Restores the Effectiveness of Chemotherapeutic Agents in Human Colon Adenocarcinoma and Pleural Mesothelioma Cells by Mungo, Eleonora, Bergandi, Loredana, Salaroglio, Iris Chiara, Doublier, Sophie

“…Emerging evidence supports the idea that a dysfunction in cell metabolism could sustain a resistant phenotype in cancer cells. As the success of…”
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Hyperglycemia Promotes Chemoresistance Through the Reduction of the Mitochondrial DNA Damage, the Bax/Bcl-2 and Bax/Bcl-XL Ratio, and the Cells in Sub-G1 Phase Due to Antitumoral Drugs Induced-Cytotoxicity in Human Colon Adenocarcinoma Cells by Bergandi, Loredana, Mungo, Eleonora, Morone, Rosa, Bosco, Ornella, Rolando, Barbara, Doublier, Sophie

“…Diabetes and cancer are common, chronic, and potentially fatal diseases that frequently co-exist. Observational studies clearly indicate that the risk of…”
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Increasing intratumor C/EBP-β LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer by Salaroglio, Iris C, Gazzano, Elena, Abdullrahman, Ahmad, Mungo, Eleonora, Castella, Barbara, Abd-Elrahman, Gamal Eldein Fathy Abd-Ellatef, Massaia, Massimo, Donadelli, Massimo, Rubinstein, Menachem, Riganti, Chiara, Kopecka, Joanna

“…Triple negative breast cancer (TNBC) easily develops resistance to the first-line drug doxorubicin, because of the high levels of the drug efflux transporter…”
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Emergence of ceftazidime/avibactam resistance in KPC-3-producing Klebsiella pneumoniae in vivo by Göttig, Stephan, Frank, Denia, Mungo, Eleonora, Nolte, Anika, Hogardt, Michael, Besier, Silke, Wichelhaus, Thomas A

“…Abstract Objectives The β-lactam/β-lactamase inhibitor combination ceftazidime/avibactam is active against KPC-producing Enterobacterales. Herein, we present…”
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Mitochondrial metabolism: Inducer or therapeutic target in tumor immune-resistance? by Kopecka, Joanna, Gazzano, Elena, Castella, Barbara, Salaroglio, Iris C., Mungo, Eleonora, Massaia, Massimo, Riganti, Chiara

“…•Metabolites released from mitochondria help cancer cells to evade immune system.•Effector and immune-suppressive cells have a different mitochondria…”
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Distinct molecular mechanisms contribute to the reduction of melanoma growth and tumor pain after systemic and local depletion of alpha‐Synuclein in mice by Niederberger, Ellen, Möller, Moritz, Mungo, Eleonora, Hass, Michelle, Wilken‐Schmitz, Annett, Manderscheid, Christine, Möser, Christine V., Geisslinger, Gerd

“…Epidemiological studies show a coincidence between Parkinson's disease (PD) and malignant melanoma. It has been suggested that this relationship is due, at…”
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Increasing intratumor C/EBP-[beta] LIP and nitric oxide levels overcome resistance to doxorubicin in triple negative breast cancer by Salaroglio, Iris C, Gazzano, Elena, Abdullrahman, Ahmad, Mungo, Eleonora, Castella, Barbara, Abd-elrahman, Gamal Eldein Fathy Abd-ellatef, Massaia, Massimo, Donadelli, Massimo, Rubinstein, Menachem, Riganti, Chiara, Kopecka, Joanna

“…Background Triple negative breast cancer (TNBC) easily develops resistance to the first-line drug doxorubicin, because of the high levels of the drug efflux…”
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Klebsiella pneumoniae : Emergence of multi-drug-resistant strains in Northwest Italy by Leone, Ilaria, Mungo, Eleonora, Bisignano, Giuseppina, Chirillo, Maria Gabriella, Savoia, Dianella

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