Search Results - "Munger, K A"

Anti-inflammatory lymphokine mRNA expression in antibody-induced glomerulonephritis by Lakkis, Fadi G., Baddoura, Fady K., Cruet, Eddie N., Parekh, Kannan R., Fukunaga, Megumu, Munger, Karen A.

“…Anti-inflammatory lymphokine mRNA expression in antibody-induced glomerulonephritis. T helper subset 2 (Th2) lymphocytes produce interleukin 4 (IL-4) and…”
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Maintenance of endothelin-induced renal arteriolar constriction in rats is cyclooxygenase dependent by Munger, K A, Takahashi, K, Awazu, M, Frazer, M, Falk, S A, Conger, J D, Badr, K F

“…Influence of arachidonate cyclooxygenase (COX) products on endothelin (ET)-evoked renal vasoconstriction was assessed. In microperfused rat afferent (AA) and…”
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Transfection of Rat Kidney with Human 15-Lipoxygenase Suppresses Inflammation and Preserves Function in Experimental Glomerulonephritis by Munger, Karen A., Montero, Angel, Fukunaga, Megumu, Uda, Susumu, Yura, Takafumi, Imai, Enyu, Kaneda, Yasufumi, Valdivielso, José M., Badr, Kamal F.

“…The human 15-lipoxygenase (15-LO) gene was transfected into rat kidneys in vivo via intra-renal arterial injection. Three days later, acute (passive) or…”
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High and low affinity binding sites for endothelin on cultured rat glomerular mesangial cells by Badr, K F, Munger, K A, Sugiura, M, Snajdar, R M, Schwartzberg, M, Inagami, T

“…Endothelin contracts glomerular mesangial cells, thereby influencing glomerular size and filtration rate. Here, we demonstrate the presence of two ET-specific…”
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Localization of p35 (annexin I, lipocortin I) in normal adult rat kidney and during recovery from ischemia by McKanna, J A, Chuncharunee, A, Munger, K A, Breyer, J A, Cohen, S, Harris, R C

“…The 35-kDa protein (p35, lipocortin I, annexin I), originally discovered as a Ca(++)-dependent substrate for the EGF receptor tyrosine kinase, binds Ca++ and…”
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The effects of surgery and acute rejection on glomerular hemodynamics in the transplanted rat kidney by Munger, K A, Coffman, T M, Griffiths, R C, Fogo, A, Badr, K F

“…The effects of surgery and acute rejection on glomerular hemodynamics in the transplanted rat kidney are examined. Kidneys were transplanted from Munich-Wistar…”
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Effects of selective A1 receptor blockade on glomerular hemodynamics: involvement of renin-angiotensin system by Munger, K A, Jackson, E K

“…We examined the renal effects of a specific adenosine A1-receptor antagonist, 1,3-dipropyl-8-cyclopentylxanthine (DPCPX, 10 micrograms.kg-1.min-1 iv). Since…”
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Mediation of renal vascular effects of epidermal growth factor by arachidonate metabolites by Harris, R C, Munger, K A, Badr, K F, Takahashi, K

“…In the rat, intrarenal infusion of epidermal growth factor decreases renal blood flow and glomerular filtration rate, and epidermal growth factor (EGF) induces…”
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Glomerular hemodynamic alterations during renal nerve stimulation in rats on high- and low-salt diets by Tucker, B.J, Peterson, O.W, Munger, K.A, Bird, J.E, Mitchell, M, Pelayo, J.C, Blantz, R.C

“…Renal adrenergic nerve activity exerts a major influence on glomerular hemodynamics and tubular fluid reabsorption. Modulation of the functional expression of…”
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Cyclooxygenase-dependent mediators of renal hemodynamic function in female rats by Munger, K A, Blantz, R C

“…Previous studies have revealed a sex-dependent difference in response to cyclooxygenase inhibition in anesthetized male and female rats. Female rats have shown…”
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Consequences of acute nitric oxide synthesis inhibition in experimental glomerulonephritis by Ferrario, R, Takahashi, K, Fogo, A, Badr, K F, Munger, K A

“…To assess the functional relevance of the enhanced glomerular nitric oxide (NO) synthesis during acute nephrotoxic serum (NTS) nephritis, a NO synthesis…”
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LTA4 hydrolase expression during glomerular inflammation: correlation of immunohistochemical localization with cytokine regulation by Montero, A, Uda, S, Munger, K A, Badr, K F

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Reciprocal regulation of LTA(4) hydrolase expression in human monocytes by gamma-interferon and interleukins 4 and 13: potential relevance to leukotriene regulation in glomerular disease by Montero, A, Nassar, G M, Uda, S, Munger, K A, Badr, K F

“…Leukotriene A(4) (LTA(4)) hydrolase catalyzes the final step in the synthesis of leukotriene B(4) (LTB(4)). TH-1- and TH-2-derived cytokines may regulate…”
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A role for atrial natriuretic peptide in endothelin-induced natriuresis by Munger, K A, Sugiura, M, Takahashi, K, Inagami, T, Badr, K F

“…Systemic administration of low-dose endothelin increases urinary sodium excretion rate despite mild to moderate reductions in renal plasma flow and glomerular…”
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Evidence for reciprocal regulation of pro- and anti-inflammatory lymphokines in rat nephrotoxic serum (NTS) nephritis by Lakkis, F G, Cruet, E N, Fukunaga, M, Munger, K A

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Induction of renal arachidonate cytochrome P-450 epoxygenase after uninephrectomy: counterregulation of hyperfiltration by Takahashi, K, Harris, R C, Capdevila, J H, Karara, A, Makita, K, Jacobson, H R, Munger, K A, Badr, K F

“…After unilateral nephrectomy (UNx) in the rat, cytochrome P-450 (cP-450)-linked arachidonate enzymatic activity was markedly and specifically induced in…”
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Oxygen consumption in the kidney: Effects of nitric oxide synthase isoforms and angiotensin II by Deng, Aihua, Miracle, Cynthia M., Suarez, Jorge M., Lortie, Mark, Satriano, Joseph, Thomson, Scott C., Munger, Karen A., Blantz, Roland C.

“…Oxygen consumption in the kidney: Effects of nitric oxide synthase isoforms and angiotensin II. Oxygen mitochondrial effects consumption by the kidney (Qo2),…”
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F(2)-isoprostanes mediate high glucose-induced TGF-beta synthesis and glomerular proteinuria in experimental type I diabetes by Montero, A, Munger, K A, Khan, R Z, Valdivielso, J M, Morrow, J D, Guasch, A, Ziyadeh, F N, Badr, K F

“…The recently discovered arachidonic acid derivatives, isoprostanes, are increased in pathological conditions associated with oxidative stress, such as…”
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Vasodilatory N-methyl-D-aspartate receptors are constitutively expressed in rat kidney by AIHUA DENG, VALDIVIELSO, Jose M, MUNGER, Karen A, BLANTZ, Roland C, THOMSON, Scott C

“…N-methyl-D-aspartate receptor (NMDA-R) is an amino acid receptor and membrane calcium channel. NMDA-R is activated by binding of coagonists, L-glutamine and…”
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Increased expression of ornithine decarboxylase in distal tubules of early diabetic rat kidneys: Are polyamines paracrine hypertrophic factors? by DENG, Aihua, MUNGER, Karen A, VALDIVIELSO, Jose M, SATRIANO, Joseph, LORTIE, Mark, BLANTZ, Roland C, THOMSON, Scott C

“…Polyamines are small biogenic molecules that are essential for cell cycle entry and progression and proliferation. They can also contribute to hypertrophy. The…”
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