Search Results - "Munger, Emily"

Microglia changes associated to Alzheimer's disease pathology in aged chimpanzees by Edler, Melissa K., Sherwood, Chet C., Meindl, Richard S., Munger, Emily L., Hopkins, William D., Ely, John J., Erwin, Joseph M., Perl, Daniel P., Mufson, Elliott J., Hof, Patrick R., Raghanti, Mary Ann

“…In Alzheimer's disease (AD), the brain's primary immune cells, microglia, become activated and are found in close apposition to amyloid beta (Aβ) protein…”
Get full text

Visual discrimination and reversal learning in aged common marmosets (Callithrix jacchus) by Munger, Emily L., Takemoto, Atsushi, Raghanti, Mary Ann, Nakamura, Katsuki

“…•Aged marmosets can complete visual discrimination and reversal learning tasks.•Aged marmosets committed more errors in the beginning stages of both tasks.•The…”
Get full text

A neurochemical hypothesis for the origin of hominids by Raghanti, Mary Ann, Edler, Melissa K., Stephenson, Alexa R., Munger, Emily L., Jacobs, Bob, Hof, Patrick R., Sherwood, Chet C., Holloway, Ralph L., Lovejoy, C. Owen

“…It has always been difficult to account for the evolution of certain human characters such as language, empathy, and altruism via individual reproductive…”
Get full text

The association of astrogliosis and microglial activation with aging and Alzheimer's disease pathology in the chimpanzee brain by Edler, Melissa K., Munger, Emily L., Maycon, Hannah, Hopkins, William D., Hof, Patrick R., Sherwood, Chet C., Raghanti, Mary Ann

“…Aging and neurodegenerative disorders, such as Alzheimer's disease (AD), trigger an immune response known as glial activation in the brain. Recent evidence…”
Get full text

Comparative analysis of astrocytes in the prefrontal cortex of primates: Insights into the evolution of human brain energetics by Munger, Emily L., Edler, Melissa K., Hopkins, William D., Hof, Patrick R., Sherwood, Chet C., Raghanti, Mary Ann

“…Astrocytes are the main homeostatic cell of the brain involved in many processes related to cognition, immune response, and energy expenditure. It has been…”
Get full text

Hedonic eating, obesity, and addiction result from increased neuropeptide Y in the nucleus accumbens during human brain evolution by Raghanti, Mary Ann, Miller, Elaine N, Jones, Danielle N, Smith, Heather N, Munger, Emily L, Edler, Melissa K, Phillips, Kimberley A, Hopkins, William D, Hof, Patrick R, Sherwood, Chet C, Lovejoy, C Owen

“…The nucleus accumbens (NAc) is central to motivation and action, exhibiting one of the highest densities of neuropeptide Y (NPY) in the brain. Within the NAc,…”
Get full text

Neuron loss associated with age but not Alzheimer's disease pathology in the chimpanzee brain by Edler, Melissa K, Munger, Emily L, Meindl, Richard S, Hopkins, William D, Ely, John J, Erwin, Joseph M, Mufson, Elliott J, Hof, Patrick R, Sherwood, Chet C, Raghanti, Mary Ann

“…In the absence of disease, ageing in the human brain is accompanied by mild cognitive dysfunction, gradual volumetric atrophy, a lack of significant cell loss,…”
Get full text

Astrocytic changes with aging and Alzheimer's disease‐type pathology in chimpanzees by Munger, Emily L., Edler, Melissa K., Hopkins, William D., Ely, John J., Erwin, Joseph M., Perl, Daniel P., Mufson, Elliott J., Hof, Patrick R., Sherwood, Chet C., Raghanti, Mary Ann

“…Astrocytes are the main homeostatic cell of the central nervous system. In addition, astrocytes mediate an inflammatory response when reactive to injury or…”
Get full text

Comparative neuropathology in aging primates: A perspective by Freire‐Cobo, Carmen, Edler, Melissa K., Varghese, Merina, Munger, Emily, Laffey, Jessie, Raia, Sophia, In, Selena S., Wicinski, Bridget, Medalla, Maria, Perez, Sylvia E., Mufson, Elliott J., Erwin, Joseph M., Guevara, Elaine E., Sherwood, Chet C., Luebke, Jennifer I., Lacreuse, Agnès, Raghanti, Mary A., Hof, Patrick R.

“…While humans exhibit a significant degree of neuropathological changes associated with deficits in cognitive and memory functions during aging, non‐human…”
Get full text

Alteration to Astrocyte Density and Morphology Across Mammalia with Specific Attention to Primate Brain Evolution and Aging by Munger, Emily LaRee

“…The roles of glia in cognition, pathology, and brain evolution are becoming increasingly clear, although our understanding is far from complete. The goal of…”
Get full text