Search Results - "Munemitsu, Susan"

Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1 by Rubinfeld, B, Munemitsu, S, Clark, R, Conroy, L, Watt, K, Crosier, W J, McCormick, F, Polakis, P

“…The rap1/Krev-1 gene encodes a ras-related protein that suppresses transformation by ras oncogenes. We have purified an 88 kd GTPase activating protein (GAP),…”
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Binding of GSK3β to the APC-β-Catenin Complex and Regulation of Complex Assembly by Rubinfeld, Bonnee, Albert, Iris, Porfiri, Emilio, Fiol, Carol, Munemitsu, Susan, Polakis, Paul

“…The adenomatous polyposis coli gene (APC) is mutated in most colon cancers. The APC protein binds to the cellular adhesion molecule β-catenin, which is a…”
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Regulation of Intracellular β-Catenin Levels by the Adenomatous Polyposis Coli (APC) Tumor-Suppressor Protein by Munemitsu, Susan, Albert, Iris, Souza, Brian, Rubinfeld, Bonnee, Polakis, Paul

“…The APC tumor-suppressor protein associates with β-catenin, a cell adhesion protein that is upregulated by the WNT1 oncogene. We examined the effects of…”
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Loss of β-catenin regulation by the APC tumor suppressor protein correlates with loss of structure due to common somatic mutations of the gene by RUBINFELD, B, ALBERT, I, PORFIRI, E, MUNEMITSU, S, POLAKIS, P

“…The mutation cluster region in the APC gene defines a region of approximately 660 bp, in which the vast majority of its somatic mutations are found. These…”
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Association of the APC Gene Product with β-Catenin by Rubinfeld, Bonnee, Souza, Brian, Albert, Iris, Müller, Oliver, Chamberlain, Scott H., Masiarz, Frank R., Munemitsu, Susan, Polakis, Paul

“…Mutations in the human APC gene are linked to familial adenomatous polyposis and to the progression of sporadic colorectal and gastric tumors. To gain insight…”
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The APC Protein and E-cadherin Form Similar but Independent Complexes with α-Catenin, β-Catenin, and Plakoglobin (∗) by Rubinfeld, Bonnee, Souza, Brian, Albert, Iris, Munemitsu, Susan, Polakis, Paul

“…The tumor suppressor APC protein associates with the cadherin-binding proteins α- and β-catenin. To examine the relationship between cadherin, catenins, and…”
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Deletion of an Amino-Terminal Sequence Stabilizes β-Catenin In Vivo and Promotes Hyperphosphorylation of the Adenomatous Polyposis Coli Tumor Suppressor Protein by Munemitsu, Susan, Albert, Iris, Rubinfeld, Bonnee, Polakis, Paul

“…Regulation of cell adhesion and cell signaling by β-catenin occurs through a mechanism likely involving the targeted degradation of the protein. Deletional…”
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The APC gene product associates with microtubules in vivo and promotes their assembly in vitro by MUNEMITSU, S, SOUZA, B, MÜLLER, O, ALBERT, I, RUBINFELD, B, POLAKIS, P

“…Defects in the APC gene occur frequently in patients with familial adenomatous polyposis coli and are associated with the progression of sporadic tumors of the…”
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Expression of the hst-1 and c-kit protooncogenes in human testicular germ cell tumors by STROHMEYER, T, PETER, S, HARTMANN, M, MUNEMITSU, S, ACKERMANN, R, ULLRICH, A, SLAMON, D. J

“…Seventy testicular germ cell tumors were analyzed at the DNA and RNA levels for the c-kit, hst-1, and int-2 oncogenes using Northern and Southern blot…”
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Inositol 1,4,5-trisphosphate receptors: distinct neuronal and nonneuronal forms derived by alternative splicing differ in phosphorylation by DANOFF, S. K, FERRIS, C. D, DONATH, C, FISCHER, G. A, MUNEMITSU, S, ULLRICH, A, SNYDER, S. H, ROSS, C. A

“…We have identified two distinct transcripts of inositol 1,4,5-trisphosphate receptor by using the PCR on first-strand cDNAs from various rat tissues. The…”
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Oncogenic activation of v-kit involves deletion of a putative tyrosine-substrate interaction site by Herbst, R, Munemitsu, S, Ullrich, A

“…The transforming gene of the Hardy-Zuckerman-4 strain of feline sarcoma virus, v-kit, arose by transduction of the cellular c-kit gene, which encodes the…”
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Molecular cloning and expression of a G25K cDNA, the human homolog of the yeast cell cycle gene CDC42 by MUNEMITSU, S, INNIS, M. A, CLARK, R, MCCORMICK, F, ULLRICH, A, POLAKIS, P

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Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2 alpha kinase by Kitajewski, J, Schneider, R J, Safer, B, Munemitsu, S M, Samuel, C E, Thimmappaya, B, Shenk, T

“…The VAI RNA of adenovirus is a small, RNA polymerase III-transcribed species required for efficient translation of host cell and viral mRNAs late after…”
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The APC Protein and E-cadherin Form Similar but Independent Complexes with -Catenin, -Catenin, and Plakoglobin by Bonnee Rubinfeld, Brian Souza, Iris Albert, Susan Munemitsu, Paul Polakis

“…The tumor suppressor APC protein associates with the cadherin-binding proteins α- and β-catenin. To examine the relationship between cadherin, catenins, and…”
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Binding of GSX3beta to the APC-beta-catenin complex and regulation of complex assembly.(adematous polyposis coli gene; glycogen synthase kinase) by Rubinfeld, Bonnee, Albert, Iris, Porfiri, Emilio, Fiol, Carol, Munemitsu, Susan, Polakis, Paul

“…The adenomatous polyposis coli gene (APC) is mutated in most colon cancers. The APC protein binds to the cellular adhesion molecule [beta]-catenin, which is a…”
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Human Kidney Amiloride-Binding Protein: cDNA Structure and Functional Expression by Barbry, Pascal, Champe, Mark, Chassande, Olivier, Munemitsu, Susan, Champigny, Guy, Lingueglia, Eric, Maes, Pierrette, Frelin, Christian, Tartar, Andre, Ullrich, Axel, Lazdunski, Michael

“…Phenamil, an analog of amiloride, is a potent blocker of the epithelial Na+channel. It has been used to purify the porcine kidney amiloride-binding protein…”
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Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly by Rubinfeld, B, Albert, I, Porfiri, E, Fiol, C, Munemitsu, S, Polakis, P

“…The adenomatous polyposis coli gene (APC) is mutated in most colon cancers. The APC protein binds to the cellular adhesion molecule beta-catenin, which is a…”
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Adenovirus VAI RNA Prevents Phosphorylation of the Eukaryotic Initiation Factor 2 α Subunit Subsequent to Infection by Schneider, Robert J., Safer, Brian, Munemitsu, Susan M., Samuel, Charles E., Shenk, Thomas

“…The virus-associated VAI RNA of adenovirus is a small, RNA polymerase III-transcribed species required for efficient translation of mRNAs late after infection…”
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Biosynthesis of reovirus-specified polypeptides: effect of point mutation of the sequences flanking the 5'-proximal AUG initiator codons of the reovirus S1 and S4 genes on the efficiency of mRNA translation by Munemitsu, S M, Samuel, C E

“…The effect on translation of site-directed nucleotide substitutions around the 5'-proximal AUG initiation codon of the reovirus s1 mRNA specifying polypeptide…”
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Epidermal growth factor receptor cytoplasmic domain mutations trigger ligand-independent transformation by MASSOGLIA, S, GRAY, A, DULL, T. J, MUNEMITSU, S, HSING-JIEN KUNG, SCHLESSINGER, J, ULLRICH, A

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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