Search Results - "Munderi, P"
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Effect of cotrimoxazole prophylaxis on malaria occurrence in HIV‐infected patients on antiretroviral therapy in sub‐Saharan Africa
Published in Tropical medicine & international health (01-05-2015)“…Objective To systematically review the evidence on the effect of cotrimoxazole (CTX) on malaria in HIV‐positive individuals on antiretroviral therapy (ART)…”
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Daily co-trimoxazole prophylaxis in severely immunosuppressed HIV-infected adults in Africa started on combination antiretroviral therapy: an observational analysis of the DART cohort
Published in The Lancet (British edition) (10-04-2010)“…Summary Background Co-trimoxazole prophylaxis can reduce mortality from untreated HIV infection in Africa; whether benefits occur alongside combination…”
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Lack of effectiveness of adherence counselling in reversing virological failure among patients on long‐term antiretroviral therapy in rural Uganda
Published in HIV medicine (01-01-2020)“…Objectives The current World Health Organization and Uganda Ministry of Health HIV treatment guidelines recommend that asymptomatic patients who have a viral…”
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Assessment of arterial elasticity among HIV‐positive participants with high CD4 cell counts: a substudy of the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial
Published in HIV medicine (01-04-2015)“…Objectives Both HIV infection and antiretroviral therapy (ART) may increase cardiovascular disease (CVD) risk. Assessments of vascular function and structure…”
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Pharmacokinetics of Lopinavir-Ritonavir with and without Nonnucleoside Reverse Transcriptase Inhibitors in Ugandan HIV-Infected Adults
Published in Antimicrobial Agents and Chemotherapy (01-07-2010)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Residual Activity of Two HIV Antiretroviral Regimens Prescribed without Virological Monitoring
Published in Antimicrobial Agents and Chemotherapy (01-10-2011)“…Virological residual activity (VRA) denotes the degree of HIV RNA suppression achieved by antiretroviral therapy in the presence of resistant virus. This…”
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Phenotypic and genotypic analyses to guide selection of reverse transcriptase inhibitors in second-line HIV therapy following extended virological failure in Uganda
Published in Journal of antimicrobial chemotherapy (01-07-2014)“…We investigated phenotypic and genotypic resistance after 2 years of first-line therapy with two HIV treatment regimens in the absence of virological…”
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Evaluation of affordable screening markers to detect CD4+ T-cell counts below 200 cells/μl among HIV-1-infected Ugandan adults
Published in Tropical medicine & international health (01-04-2010)“…To evaluate validity of WHO staging, low body mass index (BMI) and anaemia in detecting HIV-infected adults with CD4+ T-cell counts < 200 cells/μl. Between…”
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Nevirapine/zidovudine/lamivudine has superior immunological and virological responses not reflected in clinical outcomes in a 48‐week randomized comparison with abacavir/zidovudine/lamivudine in HIV‐infected Ugandan adults with low CD4 cell counts
Published in HIV medicine (01-05-2010)“…Background Triple nucleoside reverse transcriptase inhibitor regimens have advantages as first‐line antiretroviral therapy (ART), avoiding hepatotoxicity and…”
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DART and laboratory monitoring of HIV treatment – Authors' reply
Published in The Lancet (British edition) (2010)“…[...] programmes modelled on DART clinical monitoring will still need to build, staff, and equip laboratories to provide essential tests. [...] although the…”
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Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trial
Published in The Lancet (British edition) (09-01-2010)“…Summary Background HIV antiretroviral therapy (ART) is often managed without routine laboratory monitoring in Africa; however, the effect of this approach is…”
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Expert consensus statement on the science of HIV in the context of criminal law
Published in Journal of the International AIDS Society (01-07-2018)“…Introduction Globally, prosecutions for non‐disclosure, exposure or transmission of HIV frequently relate to sexual activity, biting, or spitting. This…”
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Severe Renal Dysfunction and Risk Factors Associated with Renal Impairment in HIV-Infected Adults in Africa Initiating Antiretroviral Therapy
Published in Clinical infectious diseases (15-04-2008)“…Background. We sought to investigate renal function in previously untreated symptomatic human immunodeficiency virus (HIV)–infected adults with CD4+ cell…”
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Predicting patterns of long-term CD4 reconstitution in HIV-infected children starting antiretroviral therapy in sub-Saharan Africa: a cohort-based modelling study
Published in PLoS medicine (01-10-2013)“…Long-term immune reconstitution on antiretroviral therapy (ART) has important implications for HIV-infected children, who increasingly survive into adulthood…”
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CYP2B6 c.983T>C polymorphism is associated with nevirapine hypersensitivity in Malawian and Ugandan HIV populations
Published in Journal of antimicrobial chemotherapy (01-12-2014)“…Nevirapine, an NNRTI used in HIV treatment, can cause hypersensitivity reactions in 6%-10% of patients. In the most serious cases (1.3%) this can manifest as…”
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Pubertal development in HIV-infected African children on first-line antiretroviral therapy
Published in AIDS (London) (13-03-2015)“…OBJECTIVES:To estimate age at attaining Tanner stages in Ugandan/Zimbabwean HIV-infected children initiating antiretroviral therapy (ART) in older childhood…”
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Baseline Inflammatory Biomarkers Identify Subgroups of HIV-Infected African Children With Differing Responses to Antiretroviral Therapy
Published in The Journal of infectious diseases (15-07-2016)“…Background. Identifying determinants of morbidity and mortality may help target future interventions for human immunodeficiency virus (HIV)-infected children…”
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High Rate of HIV Resuppression After Viral Failure on First-line Antiretroviral Therapy in the Absence of Switch to Second-line Therapy
Published in Clinical infectious diseases (01-04-2014)“…In a randomized comparison of nevirapine or abacavir with zidovudine plus lamivudine, routine viral load monitoring was not performed, yet 27% of individuals…”
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Phylogenetic analysis of HIV-1 shows frequent cross-country transmission and local population expansions
Published in Virus evolution (2021)“…Abstract Understanding of pandemics depends on the characterization of pathogen collections from well-defined and demographically diverse cohorts. Since its…”
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