Search Results - "Munday, H."
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Enantioselective Aza-Heck Cyclizations of N‑(Tosyloxy)carbamates: Synthesis of Pyrrolidines and Piperidines
Published in Journal of the American Chemical Society (27-02-2019)“…Pd(0)-systems modified with SPINOL-derived phosphoramidate ligands promote highly enantioselective aza-Heck cyclizations of alkenyl N-(tosyloxy)carbamates…”
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Palladium-Catalyzed Method for the Synthesis of Carbazoles via Tandem C−H Functionalization and C−N Bond Formation
Published in Journal of organic chemistry (03-10-2008)“…The development of a new method for the assembly of unsymmetrical carbazoles is reported. The strategy involves the selective intramolecular functionalization…”
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Palladium-Catalyzed Aminocarbonylation of Aryl Chlorides at Atmospheric Pressure: The Dual Role of Sodium Phenoxide
Published in Angewandte Chemie (International ed.) (01-01-2007)“…No pressure, no worries: A general, functional‐group‐tolerant, mild system for the Pd‐catalyzed carbonylation of aryl chlorides to the corresponding amides has…”
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The contribution of food science to nutrition science through reformulation in the last 50 years and into the future
Published in Nutrition bulletin (01-12-2017)“…Eating, shopping and cooking habits have radically changed over the last 50 years. This paper examines a number of food categories that have developed…”
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Remote Stereocontrol in [3,3]-Sigmatropic Rearrangements: Application to the Total Synthesis of the Immunosuppressant Mycestericin G
Published in Organic letters (03-02-2012)“…The Ireland–Claisen [3,3]-sigmatropic rearrangement has been used to access biologically important β,β′-dihydroxy α-amino acids. The rearrangement reported is…”
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Development and Proof of Concept for a Large-Scale Photoredox Additive-Free Minisci Reaction
Published in Organic process research & development (15-01-2021)Get full text
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Rapid virtual screening of enantioselective catalysts using CatVS
Published in Nature catalysis (01-01-2019)“…The development of computational tools to support organic synthesis, including the prediction of reaction pathways, optimization and selectivity, is a topic of…”
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Asymmetric Synthesis of 6′-Hydroxyarenarol: The Proposed Biosynthetic Precursor to Popolohuanone E
Published in Journal of organic chemistry (17-10-2008)“…The first synthesis of (+)-6′-hydroxyarenarol 3, the proposed biogenetic precursor to popolohuanone E (1), is described. An enantioselective route to key…”
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Effect of lung cancer surgery on quality of life
Published in Thorax (01-03-2005)“…Background: Health related quality of life (HRQOL) after surgery is important, although very limited data are available on the QOL after lung cancer surgery…”
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Approaches to Synthesis and Isolation of Enantiomerically Pure Biologically Active Atropisomers
Published in Accounts of chemical research (18-10-2022)“…Conspectus Atropisomerism is a stereochemical phenomenon exhibited by molecules containing a rotationally restricted σ bond. Contrary to classical point…”
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Spanish Terms for Cleft Lip Within the United States
Published in The Cleft palate-craniofacial journal (21-10-2024)“…To examine Spanish terms used for "cleft lip" within the United States. Perceived acceptability of these terms was also considered. An online survey was…”
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Palladium-Catalyzed Carbonylation of Aryl Tosylates and Mesylates
Published in Journal of the American Chemical Society (05-03-2008)“…A general protocol for the palladium-catalyzed carbonylation of aryl tosylates and mesylates to form esters has been developed using a catalyst system derived…”
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Copper-Catalyzed Racemization-Recycle of a Quaternary Center and Optimization Using a Combined Kinetics-DoE/MLR Modeling Approach
Published in Journal of organic chemistry (05-05-2023)“…The copper-catalyzed racemization of a complex, quaternary center of a key intermediate on route to lanabecestat has been identified. Optimization and…”
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Enantioselective Synthesis of Atropisomeric Biaryls using Biaryl 2,5‐Diphenylphospholanes as Ligands for Palladium‐Catalysed Suzuki‐Miyaura Reactions
Published in Advanced synthesis & catalysis (05-01-2021)“…Here we describe the development of biaryl 2,5‐diphenylphospholanes as a new class of C2‐symmetric, monodentate ligands for asymmetric Suzuki‐Miyaura (ASM)…”
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Iridium‐Catalyzed Asymmetric Hydrogenation of N‐Alkyl α‐Aryl Furan‐Containing Imines: an Efficient Route to Unnatural N‐Alkyl Arylalanines and Related Derivatives
Published in Advanced synthesis & catalysis (01-02-2019)“…High throughput experimentation (HTE) has enabled the rapid identification of ligand/precatalyst combinations that facilitate highly enantioselective…”
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Picolinamides as Effective Ligands for Copper-Catalysed Aryl Ether Formation: Structure-Activity Relationships, Substrate Scope and Mechanistic Investigations
Published in Chemistry : a European journal (22-12-2014)“…The use of picolinic acid amide derivatives as an effective family of bidentate ligands for copper‐catalysed aryl ether synthesis is reported. A…”
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Green Chemistry Articles of Interest to the Pharmaceutical Industry
Published in Organic process research & development (18-02-2022)Get full text
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Vinyldimethylphenylsilanes as Safety Catch Silanols in Fluoride-Free Palladium-Catalyzed Cross-Coupling Reactions
Published in Journal of organic chemistry (10-12-2004)“…A series of five structurally diverse vinyldimethylphenylsilanes have been shown to undergo a fluoride-free one-pot palladium-catalyzed cross-coupling reaction…”
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Green Chemistry Articles of Interest to the Pharmaceutical Industry
Published in Organic process research & development (16-04-2021)Get full text
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