Search Results - "Mundade, Rasika"

Protein arginine methylation of non-histone proteins and its role in diseases by Wei, Han, Mundade, Rasika, Lange, Kevin, Lu, Tao

“…Protein arginine methyltransferases (PRMTs) are a family of enzymes that can methylate arginine residues on histones and other proteins. PRMTs play a crucial…”
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Role of ChIP-seq in the discovery of transcription factor binding sites, differential gene regulation mechanism, epigenetic marks and beyond by Mundade, Rasika, Ozer, Hatice Gulcin, Wei, Han, Prabhu, Lakshmi, Lu, Tao

“…Many biologically significant processes, such as cell differentiation and cell cycle progression, gene transcription and DNA replication, chromosome stability…”
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Using VBIM Technique to Discover ARMC4/ODAD2 as a Novel Negative Regulator of NF-κB and a New Tumor Suppressor in Colorectal Cancer by Martin, Matthew, Mundade, Rasika, Hartley, Antja-Voy, Jiang, Guanglong, Jin, Jiamin, Sun, Steven, Safa, Ahmad, Sandusky, George, Liu, Yunlong, Lu, Tao

“…Since nuclear factor (NF) κB plays pivotal roles in inflammation and cancer, understanding its regulation holds great promise for disease therapy. Using the…”
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Genetic pathways, prevention, and treatment of sporadic colorectal cancer by Mundade, Rasika, Imperiale, Thomas F, Prabhu, Lakshmi, Loehrer, Patrick J, Lu, Tao

“…Epithelial cancer of the colon and rectum, also known as colorectal cancer (CRC), results from a progressive accumulation of genetic and epigenetic alterations…”
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Adenomatous Polyposis Coli‐like protein (APCLP) Functions as a Novel Negative Regulator of NF‐kB Signaling in Colon Cancer Cells by Martin, Matthew, Mundade, Rasika, Lu, Tao

“…Colon cancer (CRC) is the second leading cause of cancer related deaths in the United States. CRC is marked by aberrantly activated signaling of the nuclear…”
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Abstract 5273: VBIM technology identifies beta-catenin-like protein (BCLP) as a novel negative regulator of NF-kB by Mundade, Rasika, Lu, Tao

“…Abstract Colon cancer is the second leading cause of cancer related deaths in the United States. The nuclear factor kB (NF-kB) is an important family of…”
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Critical role of NF-κB in pancreatic cancer by Prabhu, Lakshmi, Mundade, Rasika, Korc, Murray, Loehrer, Patrick J, Lu, Tao

“…Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, and in spite of intense efforts there are limited therapeutic options for patients…”
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Abstract 4475: Adenomatous polyposis coli like protein (APCLP) functions as a novel negative regulator of NF-kB signaling in colon cancer cells by Martin, Matthew, Mundade, Rasika, Lu, Tao

“…Abstract Colon cancer (CRC) is the second leading cause of cancer related deaths in the United States. CRC is marked by aberrantly activated signaling of the…”
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PRMT5-mediated methylation of YBX1 regulates NF-κB activity in colorectal cancer by Hartley, Antja-Voy, Wang, Benlian, Mundade, Rasika, Jiang, Guanglong, Sun, Mengyao, Wei, Han, Sun, Steven, Liu, Yunlong, Lu, Tao

“…The multifunctional protein Y-box binding protein 1 (YBX1), is a critical regulator of transcription and translation, and is widely recognized as an oncogenic…”
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Abstract 3346: PRMT5-mediated methylation of YBX1 regulates NF-kB activity in colorectal cancer by Hartley, Antja-Voy, Wang, Benlian, Miyagi, Masaru, Mundade, Rasika, Hamilton, James, Lu, Tao

“…Abstract Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the US with a staggeringly less than 14% survival rate for patients…”
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Critical role of phosphorylation of serine 165 of YBX1 on the activation of NF-κB in colon cancer by Prabhu, Lakshmi, Mundade, Rasika, Wang, Benlian, Wei, Han, Hartley, Antja-Voy, Martin, Matthew, McElyea, Kyle, Temm, Constance J, Sandusky, George, Liu, Yunlong, Lu, Tao

“…Y-box binding protein 1 [YBX1] is a multifunctional protein known to facilitate many of the hallmarks of cancer. Elevated levels of YBX1 protein are highly…”
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