Search Results - "Munck, Martina"

Nesprin interchain associations control nuclear size by Lu, Wenshu, Schneider, Maria, Neumann, Sascha, Jaeger, Verena-Maren, Taranum, Surayya, Munck, Martina, Cartwright, Sarah, Richardson, Christine, Carthew, James, Noh, Kowoon, Goldberg, Martin, Noegel, Angelika A, Karakesisoglou, Iakowos

“…Nesprins-1/-2/-3/-4 are nuclear envelope proteins, which connect nuclei to the cytoskeleton. The largest nesprin-1/-2 isoforms (termed giant) tether F-actin…”
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Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin by Lüke, Yvonne, Zaim, Hafida, Karakesisoglou, Iakowos, Jaeger, Verena M, Sellin, Lorenz, Lu, Wenshu, Schneider, Maria, Neumann, Sascha, Beijer, Asa, Munck, Martina, Padmakumar, V.C, Gloy, Joachim, Walz, Gerd, Noegel, Angelika A

“…Giant isoforms, encoded by Nesprin-1 (Syne1) and Nesprin-2 (Syne2), are multifunctional actin-binding and nuclear-envelope-associated proteins belonging to the…”
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Mutations in LMNA modulate the lamin A--Nesprin-2 interaction and cause LINC complex alterations by Yang, Liu, Munck, Martina, Swaminathan, Karthic, Kapinos, Larisa E, Noegel, Angelika A, Neumann, Sascha

“…In eukaryotes the genetic material is enclosed by a continuous membrane system, the nuclear envelope (NE). Along the NE specific proteins assemble to form…”
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NUANCE, a giant protein connecting the nucleus and actin cytoskeleton by Zhen, Yen-Yi, Libotte, Thorsten, Munck, Martina, Noegel, Angelika A, Korenbaum, Elena

“…NUANCE (NUcleus and ActiN Connecting Element) was identified as a novel protein with an alpha-actinin-like actin-binding domain. A human 21.8 kb cDNA of NUANCE…”
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Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope by Libotte, Thorsten, Zaim, Hafida, Abraham, Sabu, Padmakumar, V C, Schneider, Maria, Lu, Wenshu, Munck, Martina, Hutchison, Christopher, Wehnert, Manfred, Fahrenkrog, Birthe, Sauder, Ursula, Aebi, Ueli, Noegel, Angelika A, Karakesisoglou, Iakowos

“…The vertebrate proteins Nesprin-1 and Nesprin-2 (also referred to as Enaptin and NUANCE) together with ANC-1 of Caenorhabditis elegans and MSP-300 of…”
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Nesprin-2 Interacts with Condensin Component SMC2 by Eichinger, Ludwig, Neumann, Sascha, Noegel, Angelika A., Unnikannan, C. P., Mohr, Clara, Herzog, Alexandra, Munck, Martina, Hao, Linlin, Mroß, Carmen, Xing, Xin, Kelkar, Pranav

“…The nuclear envelope proteins, Nesprins, have been primarily studied during interphase where they function in maintaining nuclear shape, size, and positioning…”
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Cytoskeletal Interactions at the Nuclear Envelope Mediated by Nesprins by Taranum, Surayya, Sur, Ilknur, Müller, Rolf, Lu, Wenshu, Rashmi, R. N., Munck, Martina, Neumann, Sascha, Karakesisoglou, Iakowos, Noegel, Angelika A.

“…Nesprin-1 is a giant tail-anchored nuclear envelope protein composed of an N-terminal F-actin binding domain, a long linker region formed by multiple spectrin…”
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SREBP-1 Mediates Activation of the Low Density Lipoprotein Receptor Promoter by Insulin and Insulin-like Growth Factor-I by Streicher, R, Kotzka, J, Müller-Wieland, D, Siemeister, G, Munck, M, Avci, H, Krone, W

“…Transcription of the low density lipoprotein (LDL) receptor gene is regulated by intracellular cholesterol concentration, hormones, and growth factors. We…”
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Sterol regulatory element binding proteins (SREBP)-1a and SREBP-2 are linked to the MAP-kinase cascade by Kotzka, J, Müller-Wieland, D, Roth, G, Kremer, L, Munck, M, Schürmann, S, Knebel, B, Krone, W

“…The classic sterol regulatory cis element (sre-1) in the LDL receptor promoter mediates sterol regulatory element binding protein (SREBP)-binding and the…”
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Depletion of Nesprin-2 is associated with an embryonic lethal phenotype in mice by Mroß, Carmen, Marko, Marija, Munck, Martina, Glöckner, Gernot, Motameny, Susanne, Altmüller, Janine, Noegel, Angelika A., Eichinger, Ludwig, Peche, Vivek S., Neumann, Sascha

“…Nesprin-2 is a nuclear envelope component and provides a link between cytoskeletal components of the cytoplasm and the nucleoplasm. Several isoforms are…”
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Nesprin-2 giant safeguards nuclear envelope architecture in LMNA S143F progeria cells by Kandert, Sebastian, Lüke, Yvonne, Kleinhenz, Tobias, Neumann, Sascha, Lu, Wenshu, Jaeger, Verena M., Munck, Martina, Wehnert, Manfred, Müller, Clemens R., Zhou, Zhongjun, Noegel, Angelika A., Dabauvalle, Marie-Christine, Karakesisoglou, Iakowos

“…The S143F lamin A/C point mutation causes a phenotype combining features of myopathy and progeria. We demonstrate here that patient dermal fibroblast cells…”
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Nesprin-2 mediated nuclear trafficking and its clinical implications by Kelkar, Pranav, Walter, Anna, Papadopoulos, Symeon, Mroß, Carmen, Munck, Martina, Peche, Vivek S, Noegel, Angelika A

“…Nuclear translocation of proteins has a crucial role in the pathogenesis of cancer, Alzheimer disease and viral infections. A complete understanding of nuclear…”
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ADD1/SREBP-1c Mediates Insulin-Induced Gene Expression Linked to the MAP Kinase Pathway by Kotzka, Jörg, Müller-Wieland, Dirk, Koponen, Anni, Njamen, Dieudonne, Kremer, Lorena, Roth, Gunther, Munck, Martina, Knebel, Birgit, Krone, Wilhelm

“…The aim of this study was to define the role of sterol regulatory element binding protein (SREBP)-1c, the human homologue to ADD1 (adipocyte determination- and…”
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Nesprin-2 giant safeguards nuclear envelope architecture in LMNA S143F progeria cells by Kandert, Sebastian, Lüke, Yvonne, Kleinhenz, Tobias, Neumann, Sascha, Lu, Wenshu, Jaeger, Verena M., Munck, Martina, Wehnert, Manfred, Müller, Clemens R., Zhou, Zhongjun, Noegel, Angelika A., Dabauvalle, Marie-Christine, Karakesisoglou, Iakowos

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Growth of Hodgkin cell lines in severely combined immunodeficient mice by von Kalle, C, Wolf, J, Becker, A, Sckaer, A, Munck, M, Engert, A, Kapp, U, Fonatsch, C, Komitowski, D, Feaux de Lacroix, W

“…No animal model exists for the in vivo growth of Hodgkin's-lymphoma-derived cells. Neither unmanipulated Hodgkin's-disease(HD)-derived cell lines nor primary…”
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