Search Results - "Munawar, Nayla"
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Analysis of SARS-CoV-2 RNA-dependent RNA polymerase as a potential therapeutic drug target using a computational approach
Published in Journal of translational medicine (07-07-2020)“…The Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) outbreak originating in Wuhan, China, has raised global health concerns and the…”
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2
PRC1 Protein Subcomplexes Architecture: Focus on the Interplay between Distinct PCGF Subunits in Protein Interaction Networks
Published in International journal of molecular sciences (11-09-2024)“…The six PCGF proteins (PCGF1-6) define the biochemical identity of Polycomb repressor complex 1 (PRC1) subcomplexes. While structural and functional studies of…”
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3
GMOs or non-GMOs? The CRISPR Conundrum
Published in Frontiers in plant science (09-10-2023)“…CRISPR-Cas9, the “genetic scissors”, is being presaged as a revolutionary technology, having tremendous potential to create designer crops by introducing…”
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4
Unraveling the complex interplay between obesity and vitamin D metabolism
Published in Scientific reports (30-03-2024)“…Vitamin D deficiency and obesity are a worldwide health issue. Obesity refers to the accumulation of excessive fats in the body which could lead to the…”
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5
Modulation of Gut Microbial Diversity through Non-Pharmaceutical Approaches to Treat Schizophrenia
Published in International journal of molecular sciences (27-02-2022)“…Schizophrenia (SCZ) is a psychotic syndrome with well-defined signs and symptoms but indecisive causes and effective treatment. Unknown underpinning reasons…”
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Hidden Role of Gut Microbiome Dysbiosis in Schizophrenia: Antipsychotics or Psychobiotics as Therapeutics?
Published in International journal of molecular sciences (18-07-2021)“…Schizophrenia is a chronic, heterogeneous neurodevelopmental disorder that has complex symptoms and uncertain etiology. Mounting evidence indicates the…”
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7
Quest for malaria management using natural remedies
Published in Frontiers in pharmacology (26-06-2024)“…Malaria, transmitted through the bite of a -infected mosquito, remains a significant global health concern. This review examines the complex life cycle of ,…”
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An Outlook on Global Regulatory Landscape for Genome-Edited Crops
Published in International journal of molecular sciences (29-10-2021)“…The revolutionary technology of CRISPR/Cas systems and their extraordinary potential to address fundamental questions in every field of biological sciences has…”
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Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells
Published in Molecular & cellular proteomics (01-11-2016)“…Polycomb proteins assemble to form complexes with important roles in epigenetic regulation. The Polycomb Repressive Complex 2 (PRC2) modulates the di- and…”
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10
Association of SLCO1B1 gene variants with angiotensin-converting enzyme inhibitor-induced cough in a Pakistani hypertensive cohort
Published in Frontiers in pharmacology (04-09-2024)“…Angiotensin-converting enzyme inhibitors (ACEIs) are prescribed for individuals with high cardiovascular (CV) risk; however, persistent cough limits the use of…”
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11
Host-pathogen interaction in arthropod vectors: Lessons from viral infections
Published in Frontiers in immunology (31-01-2023)“…Haematophagous arthropods can harbor various pathogens including viruses, bacteria, protozoa, and nematodes. Insects possess an innate immune system comprising…”
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12
Using Multiplexed CRISPR/Cas9 for Suppression of Cotton Leaf Curl Virus
Published in International journal of molecular sciences (21-11-2021)“…In recent decades, Pakistan has suffered a decline in cotton production due to several factors, including insect pests, cotton leaf curl disease (CLCuD), and…”
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13
SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18[S]
Published in Molecular & cellular proteomics (01-07-2019)“…Endogenous immunoprecipitation was used to investigate protein interactions of SETD1A complex subunits. An unexpected interaction with the DNA damage protein…”
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14
Dietary Supplementation of Microbial Dextran and Inulin Exerts Hypocholesterolemic Effects and Modulates Gut Microbiota in BALB/c Mice Models
Published in International journal of molecular sciences (01-03-2023)“…Microbial exopolysaccharides (EPSs), having great structural diversity, have gained tremendous interest for their prebiotic effects. In the present study, mice…”
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15
Fam60a defines a variant Sin3a‐Hdac complex in embryonic stem cells required for self‐renewal
Published in The EMBO journal (01-08-2017)“…Sin3a is the central scaffold protein of the prototypical Hdac1/2 chromatin repressor complex, crucially required during early embryonic development for the…”
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16
Autophagy: A New Avenue and Biochemical Mechanisms to Mitigate the Climate Change
Published in Scientifica (Cairo) (2024)“…Autophagy is a preserved process in eukaryotes that allows large material degeneration and nutrient recovery via vacuoles or lysosomes in cytoplasm. Autophagy…”
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Pathogenetic Mechanisms of Liver-Associated Injuries, Management, and Current Challenges in COVID-19 Patients
Published in Biomolecules (Basel, Switzerland) (03-01-2023)“…The global outbreak of COVID-19 possesses serious challenges and adverse impacts for patients with progression of chronic liver disease and has become a major…”
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Whole Genome Sequence Analysis of a Novel Apilactobacillus Species from Giant Honeybee ( Apis dorsata ) Gut Reveals Occurrence of Genetic Elements Coding Prebiotic and Probiotic Traits
Published in Microorganisms (Basel) (26-04-2022)“…spp. are classified as obligate fructophilic lactic acid bacteria (FLAB) that inhabit fructose-rich niches such as honeybee gut. Lactic acid bacteria are an…”
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19
Identification of Edible Fish Species of Pakistan Through DNA Barcoding
Published in Frontiers in Marine Science (04-11-2020)“…Fish is a fundamentally healthy food, loaded with essential nutrients, high protein content, vitamin D, and omega-three fatty acid. Mislabeling is a common…”
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Overexpression in a non-native halophilic host and biotechnological potential of NAD+-dependent glutamate dehydrogenase from Halobacterium salinarum strain NRC-36014
Published in Extremophiles : life under extreme conditions (01-05-2012)“…Enzymes produced by halophilic archaea are generally heat resistant and organic solvent tolerant, and accordingly important for biocatalytic applications in…”
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