Reproducibility of the 75 g oral glucose tolerance test for the diagnosis of gestational diabetes mellitus in a sub-Saharan African population

To evaluate the reproducibility of the 75 g oral glucose tolerance test and factors associated with non-reproducible results in Cameroonian pregnant women. Twenty-seven of the 84 participants (32.1%) who did the first oral glucose tolerance test were diagnosed with gestational diabetes mellitus. The...

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Bibliographic Details
Published in:	BMC research notes Vol. 10; no. 1; p. 622
Main Authors:	Munang, Yvonne Nangeh, Noubiap, Jean Jacques, Danwang, Celestin, Sama, Julius Dohbit, Azabji-Kenfack, Marcel, Mbanya, Jean Claude, Sobngwi, Eugene
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 28-11-2017 BioMed Central BMC
Subjects:	Adolescent Adult Africa Cameroon Care and treatment Diabetes in pregnancy Diabetes, Gestational - diagnosis Diagnosis Female Gestational diabetes Glucose Tolerance Test - standards Glucose tolerance tests Health aspects Humans Middle Aged Oral glucose tolerance test Pregnancy Reproducibility Reproducibility of Results Research Note Young Adult South Africa Oral glucose tolerance test Cameroon Gestational diabetes Reproducibility Africa
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Summary:	To evaluate the reproducibility of the 75 g oral glucose tolerance test and factors associated with non-reproducible results in Cameroonian pregnant women. Twenty-seven of the 84 participants (32.1%) who did the first oral glucose tolerance test were diagnosed with gestational diabetes mellitus. There was no difference between the means of the glycaemic responses at T0 (p = 0.64), T30 (p = 0.08), T60 (p = 0.86), T90 (p = 0.51), and T120 (p = 0.34) between the two oral glucose tolerance test. Age (p = 0.001) and BMI (p = 0.001) were significantly associated with non-reproducible results. The reproducibility of the oral glucose tolerance test in this study was 74.2%, and the kappa statistic's 0.46. In conclusion, the results of the oral glucose tolerance test were reproducible in only 74.2% of pregnant women in this study. This highlights that a single oral glucose tolerance test for the diagnosis of gestational diabetes mellitus should be interpreted with caution.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1756-0500 1756-0500
DOI:	10.1186/s13104-017-2944-7