Search Results - "Munín, Javier"

A comparative synthesis of 6-benzyl-2,3-dihydroimidazo[2,1-a]phthalazine and 2H-7-benzyl-3,4-dihydropyrimido[2,1-a]phthalazine by Munín, Javier, Santana, Lourdes, Uriarte, Eugenio, Borges, Fernanda, Quezada, Elías

“…[Display omitted] Two new synthetic strategies have been developed for the synthesis of a new class of cyclophthalazine derivatives…”
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Potent, selective and reversible hMAO-B inhibition by benzalphthalides: Synthesis, enzymatic and cellular evaluations and virtual docking and predictive studies by Olmo, Esther del, Barboza, Bianca, Delgado-Esteban, Maria, Escala, Nerea, Jiménez-Blasco, Daniel, Lopez-Pérez, José L., Cillero de la Fuente, Laura, Quezada, Elías, Munín, Javier, Viña, Dolores, Bolaños, Juan P., Feliciano, Arturo San

“…[Display omitted] •11 BPHs inhibited hMAO-B selectively with a Selectivity Indexes (SI) ≥ 100.•1 BPH inhibited hMAO-B selectively at the sub-nanomolar level.•2…”
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Synthesis, biological evaluation and structure–activity relationships of new phthalazinedione derivatives with vasorelaxant activity by Munín, Javier, Quezada, Elías, Cuiñas, Andrea, Campos-Toimil, Manuel, Uriarte, Eugenio, Santana, Lourdes, Viña, Dolores

“…Five series of 1,4-phthalazinedione derivatives were synthesized in good yields. Vasorelaxant activity of these new derivatives was measured on either intact…”
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Synthesis and vasorelaxant and antiplatelet activities of a new series of (4-Benzylphthalazin-1-ylamino)alcohol derivatives by Munín, Javier, Quezada, Elías, Campos-Toimil, Manuel, Cano, Ernesto, Uriarte, Eugenio, Viña, Dolores

“…A new series of phthalazine derivatives was synthesized by reaction of phthalic anhydride and different substituted phenylacetic acids to yield the…”
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Discovery of new phthalazinones as vasodilator agents and novel pharmacological tools to study calcium channels by Munín, Javier, Quezada, Elías, Viña, Dolores, Uriarte, Eugenio, Delogu, Giovanna Lucía, Gil-Longo, José

“…Hydralazine has led to the synthesis of phthalazinone derivatives which induce vasorelaxation. A new series of 2-(aminoalkyl)-4-benzyl-2H-phthalazin-1-one…”
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