Search Results - "Mun, Greg"

Validation of the 3D reconstructed human skin micronucleus (RSMN) assay: an animal-free alternative for following-up positive results from standard in vitro genotoxicity assays by Pfuhler, Stefan, Downs, Thomas R, Hewitt, Nicola J, Hoffmann, Sebastian, Mun, Greg C, Ouedraogo, Gladys, Roy, Shambhu, Curren, Rodger D, Aardema, Marilyn J

“…Abstract In vitro test batteries have become the standard approach to determine the genotoxic potential of substances of interest across industry sectors…”
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International prevalidation studies of the EpiDerm™ 3D human reconstructed skin micronucleus (RSMN) assay: Transferability and reproducibility by Aardema, Marilyn J., Barnett, Brenda C., Khambatta, Zubin, Reisinger, Kerstin, Ouedraogo-Arras, Gladys, Faquet, Brigitte, Ginestet, Anne-Claire, Mun, Greg C., Dahl, Erica L., Hewitt, Nicola J., Corvi, Raffallea, Curren, Rodger D.

“…Recently, a novel in vitro reconstructed skin micronucleus (RSMN) assay incorporating the EpiDerm™ 3D human skin model (Curren et al., Mutat. Res. 607 (2006)…”
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Evaluation of chemicals requiring metabolic activation in the EpiDerm™ 3D human reconstructed skin micronucleus (RSMN) assay by Aardema, Marilyn J., Barnett, Brenda B., Mun, Greg C., Dahl, Erica L., Curren, Rodger D., Hewitt, Nicola J., Pfuhler, Stefan

“…► The RSMN assay tested metabolically activated chemicals. ► 2 chemicals were always positive, 2 always negative. ► 1 chemical was only positive at 72h, BaP…”
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Development of a method for assessing micronucleus induction in a 3D human skin model (EpiDerm™) by Curren, Rodger D., Mun, Greg C., Gibson, David P., Aardema, Marilyn J.

“…To meet the requirements of the EU 7th Amendment to the Cosmetics Directive, manufacturers of cosmetics products will need to ascertain the safety of…”
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The reconstructed skin micronucleus assay (RSMN) in EpiDerm™: Detailed protocol and harmonized scoring atlas by Dahl, Erica L., Curren, Rodger, Barnett, Brenda C., Khambatta, Zubin, Reisinger, Kerstin, Ouedraogo, Gladys, Faquet, Brigitte, Ginestet, Anne-Claire, Mun, Greg, Hewitt, Nicola J., Carr, Greg, Pfuhler, Stefan, Aardema, Marilyn J.

“…The European Cosmetic Toiletry and Perfumery Association (COLIPA), along with contributions from the European Centre for the Validation of Alternative Methods…”
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Further development of the EpiDerm™ 3D reconstructed human skin micronucleus (RSMN) assay by Mun, Greg C., Aardema, Marilyn J., Hu, Ting, Barnett, Brenda, Kaluzhny, Yulia, Klausner, Mitchell, Karetsky, Viktor, Dahl, Erica L., Curren, Rodger D.

“…The upcoming ban on testing of cosmetics in animals by the European Union's 7th Amendment to the Cosmetics Directive will require genotoxicity safety…”
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Intralaboratory and interlaboratory evaluation of the EpiDerm™ 3D human reconstructed skin micronucleus (RSMN) assay by Hu, Ting, Kaluzhny, Yulia, Mun, Greg C., Barnett, Brenda, Karetsky, Viktor, Wilt, Nathan, Klausner, Mitchell, Curren, Rodger D., Aardema, Marilyn J.

“…A novel in vitro human reconstructed skin micronucleus (RSMN) assay has been developed using the EpiDerm™ 3D human skin model [R. D. Curren, G. C. Mun, D. P…”
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Use of the cytosensor microphysiometer to predict results of a 21-day cumulative irritation patch test in humans by Landin, Wendell E., Mun, Greg C., Nims, Raymond W., Harbell, John W.

“…The cytosensor™ microphysiometer (μϕ) was investigated as a rapid, relatively inexpensive test to predict performance of skin cleansing wipes on the human…”
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Three-tier testing approach for optimal ocular tolerance sunscreen by Narda, Mridvika, Ramos-Lopez, David, Mun, Greg, Valderas-Martinez, Palmira, Granger, Corinne

“…Background: Poor ocular tolerance of sunscreens is partially responsible for poor compliance in use of sunscreens. A three-tiered approach for the testing of…”
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Using the cytosensor microphysiometer to assess ocular toxicity by Nash, Jennifer R, Mun, Greg, Raabe, Hans A, Curren, Rodger

“…Measuring in vitro cytotoxicity is one method currently used to estimate damage to the eye after chemical exposure. The Cytosensor Microphysiometer method…”
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