Search Results - "Mumme, Hope L."

Endothelial Reprogramming by Disturbed Flow Revealed by Single-Cell RNA and Chromatin Accessibility Study by Andueza, Aitor, Kumar, Sandeep, Kim, Juyoung, Kang, Dong-Won, Mumme, Hope L., Perez, Julian I., Villa-Roel, Nicolas, Jo, Hanjoong

“…Disturbed flow (d-flow) induces atherosclerosis by regulating gene expression in endothelial cells (ECs). For further mechanistic understanding, we carried out…”
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Single cell transcriptomic landscape of diabetic foot ulcers by Theocharidis, Georgios, Thomas, Beena E., Sarkar, Debasree, Mumme, Hope L., Pilcher, William J. R., Dwivedi, Bhakti, Sandoval-Schaefer, Teresa, Sîrbulescu, Ruxandra F., Kafanas, Antonios, Mezghani, Ikram, Wang, Peng, Lobao, Antonio, Vlachos, Ioannis S., Dash, Biraja, Hsia, Henry C., Horsley, Valerie, Bhasin, Swati S., Veves, Aristidis, Bhasin, Manoj

“…Diabetic foot ulceration (DFU) is a devastating complication of diabetes whose pathogenesis remains incompletely understood. Here, we profile 174,962 single…”
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Single-cell RNA sequencing distinctly characterizes the wide heterogeneity in pediatric mixed phenotype acute leukemia by Mumme, Hope L, Raikar, Sunil S, Bhasin, Swati S, Thomas, Beena E, Lawrence, Taylor, Weinzierl, Elizabeth P, Pang, Yakun, DeRyckere, Deborah, Gawad, Chuck, Wechsler, Daniel S, Porter, Christopher C, Castellino, Sharon M, Graham, Douglas K, Bhasin, Manoj

“…Abstract Background Mixed phenotype acute leukemia (MPAL), a rare subgroup of leukemia characterized by blast cells with myeloid and lymphoid lineage features,…”
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Photopolymerized microdomains in both lipid leaflets establish diffusive transport pathways across biomimetic membranes by Makhoul-Mansour, Michelle M, El-Beyrouthy, Joyce B, Mumme, Hope L, Freeman, Eric C

“…Controlled transport within a network of aqueous subcompartments provides a foundation for the construction of biologically-inspired materials. These materials…”
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Single-Cell Profiling of Acute Myeloid Leukemia Identified ARMH1, a Novel Protein Associated with Proliferation, Migration, and Drug Resistance by Bakhtiarigheshlaghbakhtiar, Mojtaba, Bhasin, Swati S, Thomas, Beena E, Mumme, Hope L, Bhasin, Manoj

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Connecting Genetic Heterogeneity with Single-Cell Transcriptome Dysregulations in Pediatric Acute Myeloid Leukemia by Krishnan, Upaasana, Thomas, Beena E, Bhasin, Swati S, Mumme, Hope L, Bhasin, Manoj

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Single Cell RNA Sequencing Driven Characterization of Rare B/Myeloid and T/Myeloid Mixed Phenotype Acute Leukemia by Mumme, Hope L, Bhasin, Swati S, Thomas, Beena E, DeRyckere, Deborah, Castellino, Sharon M., Graham, Douglas K, Raikar, Sunil S., Bhasin, Manoj

“…Introduction: Pediatric mixed phenotype acute leukemia (MPAL), a rare subgroup of leukemia, contains features of both myeloid and lymphoid lineage blasts,…”
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A Single Cell Atlas and Interactive Web-Resource of Pediatric Cancers and Healthy Bone Marrow by Mumme, Hope L, Bhasin, Swati S, Nawaz, Mariam, Thomas, Beena E, Huang, Chenbin, DeRyckere, Deborah, Castellino, Sharon M., Wechsler, Daniel S., Raikar, Sunil S., Porter, Christopher C., Graham, Douglas K, Bhasin, Manoj

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Analysis of Single Cell Transcriptomics in Paired Pediatric T-ALL Samples Collected at Diagnosis and Following End of Induction Therapy Reveals an MRD-Associated Stem Cell Signature by Bhasin, Swati S, Thomas, Beena E, Summers, Ryan J, Sarkar, Debasree, Mumme, Hope L, Mansour, Mohammed Emam, Pilcher, William, Park, Sunita I., Castellino, Sharon M., DeRyckere, Deborah, Bhasin, Manoj, Graham, Douglas K

“…Introduction Despite recent improvement in outcomes for de novo disease, pediatric T-cell acute lymphoblastic leukemia (T-ALL) remains challenging to treat at…”
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Pediatric Single Cell Cancer Atlas: An Integrative Web-Based Resource for Single Cell Transcriptome Data from Pediatric Leukemias by Mumme, Hope L, Bhasin, Swati S, Thomas, Beena E, Dwivedi, Bhakti, DeRyckere, Deborah, Castellino, Sharon M., Wechsler, Daniel S., Raikar, Sunil S., Porter, Christopher C., Graham, Douglas K, Bhasin, Manoj

“…Introduction: The emergence and optimization of single cell profiling as a powerful tool to characterize the tumor microenvironment has revealed the…”
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