Search Results - "Mumford, R."

Oncogenic EML4-ALK assemblies suppress growth factor perception and modulate drug tolerance by Gonzalez-Martinez, David, Roth, Lee, Mumford, Thomas R., Guan, Juan, Le, Anh, Doebele, Robert C., Huang, Bo, Tulpule, Asmin, Niewiadomska-Bugaj, Magdalena, Bivona, Trever G., Bugaj, Lukasz J.

“…Drug resistance remains a challenge for targeted therapy of cancers driven by EML4-ALK and related fusion oncogenes. EML4-ALK forms cytoplasmic protein…”
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Plant viruses and viroids in the United Kingdom: An analysis of first detections and novel discoveries from 1980 to 2014 by Fox, A., Mumford, R.A.

“…•Between 1980–2014 there were 53 first records of viruses and viroids in the UK.•There were 36 were first detections and a further 17 records of previously…”
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Phytoplasma phylogenetics based on analysis of secA and 23S rRNA gene sequences for improved resolution of candidate species of 'Candidatus Phytoplasma' by Hodgetts, Jennifer, Boonham, Neil, Mumford, Rick, Harrison, Nigel, Dickinson, Matthew

“…1 School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough LE12 5RD, UK 2 Central Science Laboratory, Sand Hutton, York YO41 1LZ,…”
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The role and challenges of new diagnostic technology in plant biosecurity by Mumford, R. A., Macarthur, R., Boonham, N.

“…Pest and pathogens pose a major threat to food security and the natural environment, and these threats are moving around the globe. Trade, travel and transport…”
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The Quality of Factor Solutions in Exploratory Factor Analysis: The Influence of Sample Size, Communality, and Overdetermination by Hogarty, Kristine Y., Hines, Constance V., Kromrey, Jeffrey D., Ferron, John M., Mumford, Karen R.

“…The purpose of this studywas to investigate the relationship between sample size and the quality of factor solutions obtained from exploratory factor analysis…”
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Use of next‐generation sequencing for the identification and characterization of Maize chlorotic mottle virus and Sugarcane mosaic virus causing maize lethal necrosis in Kenya by Adams, I. P., Miano, D. W., Kinyua, Z. M., Wangai, A., Kimani, E., Phiri, N., Reeder, R., Harju, V., Glover, R., Hany, U., Souza‐Richards, R., Deb Nath, P., Nixon, T., Fox, A., Barnes, A., Smith, J., Skelton, A., Thwaites, R., Mumford, R., Boonham, N.

“…The diagnosis of novel unidentified viral plant diseases can be problematic, as the conventional methods such as real‐time PCR or ELISA may be too specific to…”
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Detection of Potato mop top virus and Tobacco rattle virus using a multiplex real-time fluorescent reverse-transcription polymerase chain reaction assay by MUMFORD, R. A, WALSH, K, BARKER, I, BOONHAM, N

“…Tobacco rattle virus (TRV) and Potato mop top virus (PMTV) are important diseases of potato that are difficult to diagnose reliably by visual symptoms…”
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Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease by Singer, II, Kawka, DW, Scott, S, Weidner, JR, Mumford, RA, Riehl, TE, Stenson, WF

“…BACKGROUND & AIMS: Inducible nitric oxide synthase (iNOS) is generated in several cell types by treatment with lipopolysaccharides or cytokines. Earlier…”
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Development of a real-time RT-PCR assay for the detection of Potato spindle tuber viroid by Boonham, N, Pérez, L.González, Mendez, M.S, Peralta, E.Lilia, Blockley, A, Walsh, K, Barker, I, Mumford, R.A

“…Potato spindle tuber viroid (PSTVd) is a quarantine pathogen in the European Union and causes damaging diseases of solanaceous crops. Under the EU Plant Health…”
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Effect of Pepino mosaic virus on the yield and quality of glasshouse-grown tomatoes in the UK by Spence, N.J, Basham, J, Mumford, R.A, Hayman, G, Edmondson, R, Jones, D.R

“…Two fully replicated trials were conducted with glasshouse-grown tomatoes, under conditions similar to commercial production, to define the impact of Pepino…”
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The partial sequencing of the genomic RNA of a UK isolate of Pepino mosaic virus and the comparison of the coat protein sequence with other isolates from Europe and Peru by MUMFORD, R. A, METCALFE, E. J

“…A 3599 nucleotide portion of the genomic RNA of a UK isolate of Pepino mosaic virus (PepMV), isolated from tomato, has been sequenced (Accession No. AF340024)…”
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Neonatal, Lethal Noncompaction of the Left Ventricular Myocardium Is Allelic with Barth Syndrome by Bleyl, Steven B., Mumford, Brian R., Thompson, Victor, Carey, John C., Pysher, Theodore J., Chin, Thomas K., Ward, Kenneth

“…Loss-of-function mutations in the G4.5gene have been shown to cause Barth syndrome (BTHS), an X-linked disorder characterized by cardiac and skeletal…”
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Use of terminal restriction fragment length polymorphism (T-RFLP) for identification of phytoplasmas in plants by Hodgetts, J, Ball, T, Boonham, N, Mumford, R, Dickinson, M

“…A terminal restriction fragment analysis (T-RFLP) technique was developed for the simple and rapid detection and diagnosis of phytoplasmas in plants. The…”
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Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints by Lark, M W, Bayne, E K, Flanagan, J, Harper, C F, Hoerrner, L A, Hutchinson, N I, Singer, I I, Donatelli, S A, Weidner, J R, Williams, H R, Mumford, R A, Lohmander, L S

“…To examine the activity of matrix metalloproteinases (MMPs) and aggrecanase in control and diseased human articular cartilage, metabolic fragments of aggrecan…”
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Optogenetic clustering and membrane translocation of the BcLOV4 photoreceptor by Pal, Ayush Aditya, Benman, William, Mumford, Thomas R, Huang, Zikang, Chow, Brian Y, Bugaj, Lukasz J

“…Optogenetic tools respond to light through one of a small number of behaviors including allosteric changes, dimerization, clustering, or membrane…”
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Calmodulin is a subunit of nitric oxide synthase from macrophages by CHO, H. J, QIAO-WEN XIE, CALAYCAY, J, MUMFORD, R. A, SWIDEREK, K. M, LEE, T. D, NATHAN, C

“…A central issue in nitric oxide (NO) research is to understand how NO can act in some settings as a servoregulator and in others as a cytotoxin. To answer…”
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Canna yellow streak virus: a new potyvirus associated with severe streaking symptoms in canna by Monger, W. A, Harju, V, Skelton, A, Seal, S. E, Mumford, R. A

“…A new potyvirus has been found in canna. A 1700-nucleotide region at the 3' end of the genomic RNA has been sequenced from two isolates. The sequence reveals…”
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Cloning and Characterization of Inducible Nitric Oxide Synthase from Mouse Macrophages by Xie, Qiao-wen, Cho, Hearn J., Calaycay, Jimmy, Mumford, Richard A., Swiderek, Kristine M., Lee, Terry D., Ding, Aihao, Troso, Tiffany, Nathan, Carl

“…Nitric oxide (NO) conveys a variety of messages between cells, including signals for vasorelaxation, neurotransmission, and cytotoxicity. In some endothelial…”
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Visual functioning restoration developments in ARMD by Mumford, R. B.

“…Recent progress in several fields has radically changed the expectations of low vision individuals. These changes augment existing prescription eye-care and…”
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First report of Chrysanthemum stem necrosis virus (CSNV) in the UK by Mumford, R. A., Jarvis, B., Morris, J., Blockley, A.

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