Search Results - "Mulvana, Helen"
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From animal models to patients: the role of placental microRNAs, miR-210, miR-126, and miR-148a/152 in preeclampsia
Published in Clinical science (1979) (01-04-2020)“…Placental microRNAs (miRNAs) regulate the placental transcriptome and play a pathological role in preeclampsia (PE), a hypertensive disorder of pregnancy…”
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Ultrasound assisted particle and cell manipulation on-chip
Published in Advanced drug delivery reviews (01-11-2013)“…Ultrasonic fields are able to exert forces on cells and other micron-scale particles, including microbubbles. The technology is compatible with existing…”
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Ultrasound mediated delivery of quantum dots from a proof of concept capsule endoscope to the gastrointestinal wall
Published in Scientific reports (28-01-2021)“…Biologic drugs, defined as therapeutic agents produced from or containing components of a living organism, are of growing importance to the pharmaceutical…”
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Investigating multi-material hydrogel three-dimensional printing for in vitro representation of the neo-vasculature of solid tumours: a comprehensive mechanical analysis and assessment of nitric oxide release from human umbilical vein endothelial cells
Published in Royal Society open science (16-08-2023)“…Many solid tumours (e.g. sarcoma, carcinoma and lymphoma) form a disorganized neo-vasculature that initiates uncontrolled vessel formation to support tumour…”
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Gelation Landscape Engineering Using a Multi-Reaction Supramolecular Hydrogelator System
Published in Journal of the American Chemical Society (18-11-2015)“…Simultaneous control of the kinetics and thermodynamics of two different types of covalent chemistry allows pathway selectivity in the formation of…”
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3D Printing of Noncytotoxic High-Resolution Microchannels in Bisphenol-A Ethoxylate Dimethacrylate Tissue-Mimicking Materials
Published in 3D printing and additive manufacturing (01-10-2023)“…The ability to create cell-laden fluidic models that mimic the geometries and physical properties of vascularized tissue would be extremely beneficial to the…”
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Single-Cell Analysis: Methods and Protocols (Methods in Molecular Biology 853, John M Walker, Series Editor)
Published in Ultrasound in Medicine & Biology (01-11-2013)Get full text
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Characterization of Contrast Agent Microbubbles for Ultrasound Imaging and Therapy Research
Published in IEEE transactions on ultrasonics, ferroelectrics, and frequency control (01-01-2017)“…The high efficiency with which gas microbubbles can scatter ultrasound compared with the surrounding blood pool or tissues has led to their widespread…”
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Ultrasound and Microbubble Gene Delivery for Targeting Altered Placental MicroRNAs in Preeclampsia
Published in Placenta (Eastbourne) (01-08-2019)Get full text
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Traditional Multiwell Plates and Petri Dishes Limit the Evaluation of the Effects of Ultrasound on Cells In Vitro
Published in Ultrasound in medicine & biology (01-09-2022)Get full text
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In Vitro Investigation of the Individual Contributions of Ultrasound-Induced Stable and Inertial Cavitation in Targeted Drug Delivery
Published in Ultrasound in medicine & biology (01-07-2015)“…Abstract Ultrasound-mediated targeted drug delivery is a therapeutic modality under development with the potential to treat cancer. Its ability to produce…”
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Modelling of magnetic microbubbles to evaluate contrast enhanced magnetomotive ultrasound in lymph nodes - a pre-clinical study
Published in British journal of radiology (01-07-2022)“…Despite advances in MRI the detection and characterisation of lymph nodes in rectal cancer remains complex, especially when assessing the response to…”
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Temperature Dependent Behavior of Ultrasound Contrast Agents
Published in Ultrasound in medicine & biology (01-06-2010)“…Abstract Recent interest in ultrasound contrast agents (UCAs) as tools for quantitative imaging and therapy has increased the need for accurate…”
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Development of Preclinical Ultrasound Imaging Techniques to Identify and Image Sentinel Lymph Nodes in a Cancerous Animal Model
Published in Cancers (22-01-2022)“…Lymph nodes (LNs) are believed to be the first organs targeted by colorectal cancer cells detached from a primary solid tumor because of their role in draining…”
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Theoretical and Experimental Characterisation of Magnetic Microbubbles
Published in Ultrasound in medicine & biology (01-05-2012)“…Abstract In addition to improving image contrast, microbubbles have shown great potential in molecular imaging and drug/gene delivery. Previous work by the…”
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Temperature-Dependent Differences in the Nonlinear Acoustic Behavior of Ultrasound Contrast Agents Revealed by High-Speed Imaging and Bulk Acoustics
Published in Ultrasound in medicine & biology (01-09-2011)“…Abstract Previous work by the authors has established that increasing the temperature of the suspending liquid from 20°C to body temperature has a significant…”
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The Influence of Gas Saturation on Microbubble Stability
Published in Ultrasound in medicine & biology (01-06-2012)“…Abstract Accurate acoustic characterisation is an essential component of any experimental investigation concerning the use and development of microbubble…”
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Single Bubble Acoustic Characterization and Stability Measurement of Adherent Microbubbles
Published in Ultrasound in medicine & biology (01-05-2013)“…Abstract This article examines how the acoustic and stability characteristics of single lipid-shelled microbubbles (MBs) change as a result of adherence to a…”
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Magnetic microbubbles for localised imaging and drug delivery: Development, characterisation and preliminary application in vivo
Published in The Journal of the Acoustical Society of America (01-04-2012)“…The use of coated microbubbles in therapeutic applications, in particular drug delivery and gene therapy, has become a highly active area of research. There…”
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Effect of Albumin and Dextrose Concentration on Ultrasound and Microbubble Mediated Gene Transfection In Vivo
Published in Ultrasound in medicine & biology (01-06-2012)“…Abstract Ultrasound and microbubble mediated gene transfection has great potential for site-selective, safe gene delivery. Albumin-based microbubbles have…”
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