Search Results - "Mulrooney‐Cousins, Patricia M."

Hepadnaviral Lymphotropism and Its Relevance to HBV Persistence and Pathogenesis by Coffin, Carla S., Mulrooney-Cousins, Patricia M., Michalak, Tomasz I.

“…Since the discovery of hepatitis B virus (HBV) over five decades ago, there have been many independent studies showing presence of HBV genomes in cells of the…”
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Primary seronegative but molecularly evident hepadnaviral infection engages liver and induces hepatocarcinoma in the woodchuck model of hepatitis B by Mulrooney-Cousins, Patricia M, Chauhan, Ranjit, Churchill, Norma D, Michalak, Tomasz I

“…Hepadnavirus at very low doses establishes in woodchucks asymptomatic, serologically undetectable but molecularly evident persistent infection. This primary…”
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Persistent occult hepatitis B virus infection： Experimental findings and clinical implications by Patricia M Mulrooney-Cousins Tomasz I Michalak

“…Hepatitis B virus （HBV） is a highly pathogenic virus that causes chronic liver diseases in millions of people globally. In addition to a symptomatic,…”
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Hepatitis B virus quasispecies in hepatic and extrahepatic viral reservoirs in liver transplant recipients on prophylactic therapy by Coffin, Carla S., Mulrooney‐Cousins, Patricia M., van Marle, Guido, Roberts, John P., Michalak, Tomasz I., Terrault, Norah A.

“…The characterization of hepatitis B virus (HBV) quasispecies in different compartments in liver transplant (LT) recipients may be helpful in optimizing…”
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Differential Expression of Woodchuck Toll-Like Receptors 1-10 in Distinct Forms of Infection and Stages of Hepatitis in Experimental Hepatitis B Virus Infection by Williams, John Bradley, Hüppner, Alena, Mulrooney-Cousins, Patricia M, Michalak, Tomasz I

“…Woodchucks infected with woodchuck hepatitis virus (WHV) represent a highly valuable model of human hepatitis B virus (HBV) infection, chronic hepatitis (CH),…”
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Identification of antibodies cross-reactive with woodchuck immune cells and activation of virus-specific and global cytotoxic T cell responses by anti-PD-1 and anti-PD-L1 in experimental chronic hepatitis B and persistent occult hepadnaviral infection by Corkum, Christopher P, Wiede, Louisa L, Ruble, Cara L-A, Qiu, Jiabin, Mulrooney-Cousins, Patricia M, Steeves, Meredith A, Watson, David E, Michalak, Tomasz I

“…Woodchuck infected with woodchuck hepatitis virus (WHV) is the most pathogenically compatible naturally occurring model of human hepatitis B virus (HBV)…”
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Intrahepatic Expression of Genes Affiliated with Innate and Adaptive Immune Responses Immediately after Invasion and during Acute Infection with Woodchuck Hepadnavirus by GUY, Clifford S, MULROONEY-COUSINS, Patricia M, CHURCHILL, Norma D, MICHALAK, Tomasz I

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Repeated Exposure to Trace Amounts of Woodchuck Hepadnavirus Induces Molecularly Evident Infection and Virus-Specific T Cell Response in the Absence of Serological Infection Markers and Hepatitis by Gujar, Shashi A, Mulrooney-Cousins, Patricia M, Michalak, Tomasz I

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Repeated Passage of Wild-Type Woodchuck Hepatitis Virus in Lymphoid Cells Does Not Generate Cell Type-Specific Variants or Alter Virus Infectivity by Patricia M. Mulrooney-Cousins, Tomasz I. Michalak

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Hepatitis C virus load and expression of a unique subset of cellular genes in circulating lymphoid cells differentiate non-responders from responders to pegylated interferon alpha-ribavirin treatment by Pham, Tram N.Q., Lin, Dolly M.H., Mulrooney-Cousins, Patricia M., Churchill, Norma D., Kowala-Piaskowska, Arleta, Mozer-Lisewska, Iwona, Machaj, Anna, Pazgan-Simon, Monika, Zalewska, Malgorzata, Simon, Krzysztof, King, Dawn, Reddy, S. Bharati, Michalak, Tomasz I.

“…Based on investigations of liver biopsy material, certain cellular genes have been implicated as correlates of success or failure to interferon alpha–ribavirin…”
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Profound suppression of chronic hepatitis C following superinfection with hepatitis B virus by Coffin, Carla S., Mulrooney‐Cousins, Patricia M., Lee, Samuel S., Michalak, Tomasz I., Swain, Mark G.

“…Background: Hepatitis B virus (HBV) and hepatitis C virus (HCV) share similar transmission routes; thus, coinfection is frequent. The consequences of acute HBV…”
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Virological characteristics of occult hepatitis B virus in a North American cohort of human immunodeficiency virus type 1-positive patients on dual active anti-HBV/HIV therapy by Coffin, Carla S, Mulrooney-Cousins, Patricia M, Osiowy, Carla, van der Meer, Frank, Nishikawa, Sandra, Michalak, Tomasz I, van Marle, Guido, Gill, M. John

“…Abstract Background Occult hepatitis B virus infection (OBI) is defined as low-level HBV DNA presence in serum, liver and/or peripheral blood mononuclear cells…”
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Asymptomatic Hepadnaviral Persistence and Its Consequences in the Woodchuck Model of Occult Hepatitis B Virus Infection by Mulrooney-Cousins, Patricia M, Michalak, Tomasz I

“…Woodchuck hepatitis virus (WHV) is molecularly and pathogenically closely related to hepatitis B virus (HBV). Both viruses display tropism towards hepatocytes…”
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Primary Seronegative but Molecularly Evident Hepadnaviral Infection Engages Liver and Induces Hepatocarcinoma in the Woodchuck Model of Hepatitis B: e1004332 by Mulrooney-Cousins, Patricia M, Chauhan, Ranjit, Churchill, Norma D, Michalak, Tomasz I

“…Hepadnavirus at very low doses establishes in woodchucks asymptomatic, serologically undetectable but molecularly evident persistent infection. This primary…”
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Profound suppression of chronic hepatitis C following superinfection with hepatitis B virus by Coffin, Carla S., Mulrooney-Cousins, Patricia M., Lee, Samuel S., Michalak, Tomasz I., Swain, Mark G.

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