Search Results - "Mulrooney, Scott B"

Nickel-dependent metalloenzymes by Boer, Jodi L., Mulrooney, Scott B., Hausinger, Robert P.

“…[Display omitted] •The function, structure, and mechanisms are described for nickel-dependent enzymes.•Nickel active sites range from simple mononuclear…”
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Inhibition of urease by bismuth(III): implications for the mechanism of action of bismuth drugs by Zhang, Li, Mulrooney, Scott B, Leung, Andy F K, Zeng, Yibo, Ko, Ben B C, Hausinger, Robert P, Sun, Hongzhe

“…Bismuth compounds are widely used for the treatment of peptic ulcers and Helicobacter pylori infections. It has been suggested that enzyme inhibition plays an…”
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Identification of Escherichia coli YgaF as an l-2-Hydroxyglutarate Oxidase by KALLIRI, Efthalia, MULROONEY, Scott B, HAUSINGER, Robert P

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The UreEF Fusion Protein Provides a Soluble and Functional Form of the UreF Urease Accessory Protein by JONG KYONG KIM, MULROONEY, Scott B, HAUSINGER, Robert P

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Biosynthesis of Active Bacillus subtilis Urease in the Absence of Known Urease Accessory Proteins by JONG KYONG KIM, MULROONEY, Scott B, HAUSINGER, Robert P

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The AidB Component of the Escherichia coli Adaptive Response to Alkylating Agents Is a Flavin-Containing, DNA-Binding Protein by ROHANKHEDKAR, Mukta S, MULROONEY, Scott B, WEDEMEYER, William J, HAUSINGER, Robert P

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Purification and Properties of the Klebsiella aerogenes UreE Metal-Binding Domain, a Functional Metallochaperone of Urease by MULROONEY, Scott B, WARD, Sarah K, HAUSINGER, Robert P

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Nickel uptake and utilization by microorganisms by Mulrooney, Scott B., Hausinger, Robert P.

“…Nickel is an essential nutrient for selected microorganisms where it participates in a variety of cellular processes. Many microbes are capable of sensing…”
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Interplay of metal ions and urease by Carter, Eric L, Flugga, Nicholas, Boer, Jodi L, Mulrooney, Scott B, Hausinger, Robert P

“…Urease, the first enzyme to be crystallized, contains a dinuclear nickel metallocenter that catalyzes the decomposition of urea to produce ammonia, a reaction…”
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Metal Ion Dependence of Recombinant Escherichia coli Allantoinase by Mulrooney, Scott B, Hausinger, Robert P

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Non-thiolate ligation of nickel by nucleotide-free UreG of Klebsiella aerogenes by Martin-Diaconescu, Vlad, Joseph, Crisjoe A., Boer, Jodi L., Mulrooney, Scott B., Hausinger, Robert P., Maroney, Michael J.

“…Nickel-dependent ureases are activated by a multiprotein complex that includes the GTPase UreG. Prior studies showed that nucleotide-free UreG from Klebsiella…”
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Thermodynamics of Ni2+, Cu2+, and Zn2+ Binding to the Urease Metallochaperone UreE by Grossoehme, Nicholas E, Mulrooney, Scott B, Hausinger, Robert P, Wilcox, Dean E

“…The two Ni2+ ions in the urease active site are delivered by the metallochaperone UreE, whose metal binding properties are central to the assembly of this…”
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The Escherichia coli alkylation response protein AidB is a redox partner of flavodoxin and binds RNA and acyl carrier protein by Mulrooney, Scott B., Howard, Michael J., Hausinger, Robert P.

“…► AidB binds flavodoxin acyl carrier protein, and RNA. ► Reduced flavodoxin can donate electrons to oxidized AidB. ► MNNG is not a substrate for AidB…”
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High-Level Expression in Escherichia coli and Purification of the Membrane-Bound Form of Cytochrome b5 by Mulrooney, Scott B., Waskell, Lucy

“…Expression of the membrane-bound form of rabbit cytochrome b5 in Escherichia coli has been significantly improved through the use of the T7 expression vector…”
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Potential Active-Site Base of Thioredoxin reductase from Escherichia coli: Examination of Histidine245 and Aspartate139 by Site-Directed Mutagenesis by Mulrooney, Scott B, Williams, Charles H

“…It has been proposed that an acid-base catalyst facilitates the reduction of thioredoxin by thioredoxin reductase from Escherichia coli [O'Donnell, M. E., &…”
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Crystal Structure of Klebsiella aerogenesUreE, a Nickel-binding Metallochaperone for Urease Activation by Song, Hyun Kyu, Mulrooney, Scott B., Huber, Robert, Hausinger, Robert P.

“…UreE is proposed to be a metallochaperone that delivers nickel ions to urease during activation of this bacterial virulence factor. Wild-type Klebsiella…”
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13C‐, 15N‐ and 31P‐NMR studies of oxidized and reduced low molecular mass thioredoxin reductase and some mutant proteins by Eisenreich, Wolfgang, Kemter, Kristina, Bacher, Adelbert, Mulrooney, Scott B., Williams, Charles H., Müller, Franz

“…Thioredoxin reductase (TrxR) from Escherichia coli, the mutant proteins E159Y and C138S, and the mutant protein C138S treated with phenylmercuric acetate were…”
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Preparation of Figure 8 and Cruciform DNAs and Their Use in Studies of the Kinetics of Branch Migration (∗) by Mulrooney, Scott B., Fishel, Richard A., Hejna, James A., Warner, Robert C.

“…We have re-examined the kinetics of the branch migration of double-stranded DNA that is mediated by the stepwise movement of the Holliday junction. This work…”
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Crystal structure of Klebsiella aerogenes UreE, a nickel-binding metallochaperone for urease activation by Song, H K, Mulrooney, S B, Huber, R, Hausinger, R P

“…UreE is proposed to be a metallochaperone that delivers nickel ions to urease during activation of this bacterial virulence factor. Wild-type Klebsiella…”
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The α-helical membrane spanning domain of cytochrome b 5 interacts with cytochrome P450 via nonspecific interactions by Mulrooney, Scott B., Meinhardt, David R., Waskell, Lucy

“…Cytochrome b 5 (cyt b 5) is an amphipathic membrane-bound heme protein found in the endoplasmic reticulum of eukaryotes. It consists of three domains, an…”
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