Search Results - "Mulroe, Fred"
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Targeting firing rate neuronal homeostasis can prevent seizures
Published in Disease models & mechanisms (01-10-2022)“…Manipulating firing-rate neuronal homeostasis, which enables neurons to regulate their intrinsic excitability, offers an attractive opportunity to prevent…”
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Journal Article -
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Pumilio: A Novel Target for the Treatment of Epilepsy
Published 01-01-2023“…Epilepsy is a condition characterised by recurrent seizures. The underlying mechanism of epileptic seizures is excessive and abnormal neuronal activity…”
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Dissertation -
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ATP6V0C variants impair V-ATPase function causing a neurodevelopmental disorder often associated with epilepsy
Published in Brain (London, England : 1878) (19-04-2023)“…Abstract The vacuolar H+-ATPase is an enzymatic complex that functions in an ATP-dependent manner to pump protons across membranes and acidify organelles,…”
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Journal Article