Search Results - "Mullish, Benjamin H"

Inhibiting Growth of Clostridioides difficile by Restoring Valerate, Produced by the Intestinal Microbiota by McDonald, Julie A.K., Mullish, Benjamin H., Pechlivanis, Alexandros, Liu, Zhigang, Brignardello, Jerusa, Kao, Dina, Holmes, Elaine, Li, Jia V., Clarke, Thomas B., Thursz, Mark R., Marchesi, Julian R.

“…Fecal microbiota transplantation (FMT) is effective for treating recurrent Clostridioides difficile infection (CDI), but there are concerns about its long-term…”
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Immunotoxicity from checkpoint inhibitor therapy: clinical features and underlying mechanisms by Fessas, Petros, Possamai, Lucia A., Clark, James, Daniels, Ella, Gudd, Cathrin, Mullish, Benjamin H., Alexander, James L., Pinato, David J.

“…Summary Immune checkpoint inhibition with monoclonal antibodies is becoming increasingly commonplace in cancer medicine, having contributed to a widening of…”
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The Intestinal Barrier and Its Dysfunction in Patients with Metabolic Diseases and Non-Alcoholic Fatty Liver Disease by Forlano, Roberta, Mullish, Benjamin H, Roberts, Lauren A, Thursz, Mark R, Manousou, Pinelopi

“…Non-alcoholic fatty liver disease (NAFLD) represents an increasing cause of liver disease worldwide, mirroring the epidemics of obesity and metabolic syndrome…”
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Gut Microbiota—A Future Therapeutic Target for People with Non-Alcoholic Fatty Liver Disease: A Systematic Review by Forlano, Roberta, Sivakumar, Mathuri, Mullish, Benjamin H., Manousou, Pinelopi

“…Non-alcoholic fatty liver disease (NAFLD) represents an increasing cause of liver disease, affecting one-third of the population worldwide. Despite many…”
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In-hospital mortality is associated with inflammatory response in NAFLD patients admitted for COVID-19 by Forlano, Roberta, Mullish, Benjamin H, Mukherjee, Sujit K, Nathwani, Rooshi, Harlow, Cristopher, Crook, Peter, Judge, Rebekah, Soubieres, Anet, Middleton, Paul, Daunt, Anna, Perez-Guzman, Pablo, Selvapatt, Nowlan, Lemoine, Maud, Dhar, Ameet, Thursz, Mark R, Nayagam, Shevanthi, Manousou, Pinelopi

“…Although metabolic risk factors are associated with more severe COVID-19, there is little evidence on outcomes in patients with non-alcoholic fatty liver…”
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The potential utility of fecal (or intestinal) microbiota transplantation in controlling infectious diseases by Ghani, Rohma, Mullish, Benjamin H., Roberts, Lauren A., Davies, Frances J., Marchesi, Julian R.

“…The intestinal microbiota is recognized to play a role in the defense against infection, but conversely also acts as a reservoir for potentially pathogenic…”
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Impact of Fecal Microbiota Transplantation on Gut Bacterial Bile Acid Metabolism in Humans by Bustamante, Jessica-Miranda, Dawson, Tyson, Loeffler, Caitlin, Marfori, Zara, Marchesi, Julian R, Mullish, Benjamin H, Thompson, Christopher C, Crandall, Keith A, Rahnavard, Ali, Allegretti, Jessica R, Cummings, Bethany P

“…Fecal microbiota transplantation (FMT) is a promising therapeutic modality for the treatment and prevention of metabolic disease. We previously conducted a…”
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A Double‐Blind, Randomized, Placebo‐Controlled Trial of Ursodeoxycholic Acid (UDCA) in Parkinson's Disease by Payne, Thomas, Appleby, Matthew, Buckley, Ellen, Gelder, Linda M.A., Mullish, Benjamin H., Sassani, Matilde, Dunning, Mark J., Hernandez, Dena, Scholz, Sonja W., McNeill, Alisdair, Libri, Vincenzo, Moll, Sarah, Marchesi, Julian R., Taylor, Rosie, Su, Li, Mazzà, Claudia, Jenkins, Thomas M., Foltynie, Thomas, Bandmann, Oliver

“…Background Rescue of mitochondrial function is a promising neuroprotective strategy for Parkinson's disease (PD). Ursodeoxycholic acid (UDCA) has shown…”
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Antibiotics promote intestinal growth of carbapenem-resistant Enterobacteriaceae by enriching nutrients and depleting microbial metabolites by Yip, Alexander Y. G., King, Olivia G., Omelchenko, Oleksii, Kurkimat, Sanjana, Horrocks, Victoria, Mostyn, Phoebe, Danckert, Nathan, Ghani, Rohma, Satta, Giovanni, Jauneikaite, Elita, Davies, Frances J., Clarke, Thomas B., Mullish, Benjamin H., Marchesi, Julian R., McDonald, Julie A. K.

“…The intestine is the primary colonisation site for carbapenem-resistant Enterobacteriaceae (CRE) and serves as a reservoir of CRE that cause invasive…”
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Antibiotic therapy and outcome from immune-checkpoint inhibitors by Pinato, David J., Gramenitskaya, Daria, Altmann, Daniel M., Boyton, Rosemary J., Mullish, Benjamin H., Marchesi, Julian R., Bower, Mark

“…Sensitivity to immune checkpoint inhibitor (ICPI) therapy is governed by a complex interplay of tumor and host-related determinants. Epidemiological studies…”
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Faecal (or intestinal) microbiota transplant: a tool for repairing the gut microbiome by Ghani, Rohma, Chrysostomou, Despoina, Roberts, Lauren A, Pandiaraja, Madhumitha, Marchesi, Julian R., Mullish, Benjamin H.

“…Faecal/intestinal microbiota transplant (FMT/IMT) is an efficacious treatment option for recurrent Clostridioides difficile infection, which has prompted…”
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Applying Lipidomics to Non-Alcoholic Fatty Liver Disease: A Clinical Perspective by Huang, Jian, Sigon, Giordano, Mullish, Benjamin H, Wang, Dan, Sharma, Rohini, Manousou, Pinelopi, Forlano, Roberta

“…The prevalence of Non-alcoholic fatty liver disease (NAFLD) and associated complications, such as hepatocellular carcinoma (HCC), is growing worldwide, due to…”
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The gut microbiome: an under-recognised contributor to the COVID-19 pandemic? by Segal, Jonathan P., Mak, Joyce W. Y., Mullish, Benjamin H., Alexander, James L., Ng, Siew C., Marchesi, Julian R.

“…The novel coronavirus infection (COVID-19) caused by the SARS-CoV-2 virus has spread rapidly across the globe, culminating in major global morbidity and…”
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3D printed rectal swabs for assessing the gut microbiome, metabolome and inflammation by Perry, Robert W., Mullish, Benjamin H., Alexander, James L., Shah, Raashi, Danckert, Nathan P., Blanco, Jesus Miguens, Roberts, Lauren, Liu, Zhigang, Chrysostomou, Despoina, Radhakrishnan, Shiva T., Balarajah, Sharmili, Barry, Rachael, Hicks, Lucy C., Williams, Horace R. T., Marchesi, Julian R.

“…Investigating the gut microbiome and metabolome frequently requires faecal samples, which can be difficult to obtain. Previous studies have shown that rectal…”
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Screening for NAFLD-Current Knowledge and Challenges by Forlano, Roberta, Sigon, Giordano, Mullish, Benjamin H, Yee, Michael, Manousou, Pinelopi

“…Non-alcoholic fatty liver disease (NAFLD) is the most common cause of abnormal liver function tests worldwide, with an estimated prevalence ranging between…”
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Rectal swabs as a viable alternative to faecal sampling for the analysis of gut microbiota functionality and composition by Radhakrishnan, Shiva T., Gallagher, Kate I., Mullish, Benjamin H., Serrano-Contreras, Jose I., Alexander, James L., Miguens Blanco, Jesus, Danckert, Nathan P., Valdivia-Garcia, Maria, Hopkins, Billy J., Ghai, Anik, Ayub, Azad, Li, Jia V., Marchesi, Julian R., Williams, Horace R. T.

“…Faecal or biopsy samples are frequently used to analyse the gut microbiota, but issues remain with the provision and collection of such samples. Rectal swabs…”
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Metabolic Profile Reflects Stages of Fibrosis in Patients with Non-Alcoholic Fatty Liver Disease by Jambulingam, Nila, Forlano, Roberta, Preston, Benjamin, Mullish, Benjamin H, Portone, Greta, Baheer, Yama, Yee, Michael, Goldin, Robert D, Thursz, Mark R, Manousou, Pinelopi

“…Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease worldwide, with fibrosis stage being the main predictor for clinical…”
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The application of omics techniques to understand the role of the gut microbiota in inflammatory bowel disease by Segal, Jonathan P., Mullish, Benjamin H., Quraishi, Mohammed Nabil, Acharjee, Animesh, Williams, Horace R. T., Iqbal, Tariq, Hart, Ailsa L., Marchesi, Julian R.

“…The aetiopathogenesis of inflammatory bowel diseases (IBD) involves the complex interaction between a patient’s genetic predisposition, environment, gut…”
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Probiotics reduce self-reported symptoms of upper respiratory tract infection in overweight and obese adults: should we be considering probiotics during viral pandemics? by Mullish, Benjamin H., Marchesi, Julian R., McDonald, Julie A.K., Pass, Daniel A., Masetti, Giulia, Michael, Daryn R., Plummer, Sue, Jack, Alison A., Davies, Thomas S., Hughes, Timothy R., Wang, Duolao

“…Gut microbiome manipulation to alter the gut-lung axis may potentially protect humans against respiratory infections, and clinical trials of probiotics show…”
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Understanding the mechanisms of efficacy of fecal microbiota transplant in treating recurrent Clostridioides difficile infection and beyond: the contribution of gut microbial-derived metabolites by Martinez-Gili, Laura, McDonald, Julie a K, Liu, Zhigang, Kao, Dina, Allegretti, Jessica R, Monaghan, Tanya M, Barker, Grace F, Miguéns Blanco, Jesús, Williams, Horace R T, Holmes, Elaine, Thursz, Mark R, Marchesi, Julian R, Mullish, Benjamin H

“…Fecal microbiota transplant (FMT) is a highly-effective therapy for recurrent Clostridioides difficile infection (rCDI), and shows promise for certain non-CDI…”
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