Search Results - "Mullins, R"

SuperPlots: Communicating reproducibility and variability in cell biology by Lord, Samuel J, Velle, Katrina B, Mullins, R Dyche, Fritz-Laylin, Lillian K

“…P values and error bars help readers infer whether a reported difference would likely recur, with the sample size n used for statistical tests representing…”
Get full text

Cell mechanics and the cytoskeleton by Fletcher, Daniel A, Mullins, R. Dyche

“…The ability of a eukaryotic cell to resist deformation, to transport intracellular cargo and to change shape during movement depends on the cytoskeleton, an…”
Get full text

Force Feedback Controls Motor Activity and Mechanical Properties of Self-Assembling Branched Actin Networks by Bieling, Peter, Li, Tai-De, Weichsel, Julian, McGorty, Ryan, Jreij, Pamela, Huang, Bo, Fletcher, Daniel A., Mullins, R. Dyche

“…Branched actin networks—created by the Arp2/3 complex, capping protein, and a nucleation promoting factor—generate and transmit forces required for many…”
Get full text

LC3 and STRAP regulate actin filament assembly by JMY during autophagosome formation by Hu, Xiaohua, Mullins, R Dyche

“…During autophagy, actin filament networks move and remodel cellular membranes to form autophagosomes that enclose and metabolize cytoplasmic contents. Two…”
Get full text

Epi-illumination SPIM for volumetric imaging with high spatial-temporal resolution by Yang, Bin, Chen, Xingye, Wang, Yina, Feng, Siyu, Pessino, Veronica, Stuurman, Nico, Cho, Nathan H., Cheng, Karen W., Lord, Samuel J., Xu, Linfeng, Xie, Dan, Mullins, R. Dyche, Leonetti, Manuel D., Huang, Bo

“…We designed an epi-illumination SPIM system that uses a single objective and has a sample interface identical to that of an inverted fluorescence microscope…”
Get full text

DNA damage induces nuclear actin filament assembly by Formin-2 and Spire-1/2 that promotes efficient DNA repair by Belin, Brittany J, Lee, Terri, Mullins, R Dyche

“…Actin filaments assemble inside the nucleus in response to multiple cellular perturbations, including heat shock, protein misfolding, integrin engagement, and…”
Get full text

Increases in anaphylaxis fatalities in Australia from 1997 to 2013 by Mullins, R. J., Wainstein, B. K., Barnes, E. H., Liew, W. K., Campbell, D. E.

“…Summary Background Recent epidemiological studies indicate increases in Australian, UK and US hospital anaphylaxis admission rates. Objectives The aim of this…”
Get full text

Drosophila Spire is an actin nucleation factor by Quinlan, M.E, Heuser, J.E, Kerkhoff, E, Mullins, R.D

“…The actin cytoskeleton is essential for many cellular functions including shape determination, intracellular transport and locomotion. Previous work has…”
Get full text

Capping Protein Increases the Rate of Actin-Based Motility by Promoting Filament Nucleation by the Arp2/3 Complex by Akin, Orkun, Mullins, R. Dyche

“…Capping protein (CP) is an integral component of Arp2/3-nucleated actin networks that drive amoeboid motility. Increasing the concentration of capping protein,…”
Get full text

VASP is a processive actin polymerase that requires monomeric actin for barbed end association by Hansen, Scott D., Mullins, R. Dyche

“…Ena/VASP proteins regulate the actin cytoskeleton during cell migration and morphogenesis and promote assembly of both filopodial and lamellipodial actin…”
Get full text

Design of Reversible, Cysteine-Targeted Michael Acceptors Guided by Kinetic and Computational Analysis by Krishnan, Shyam, Miller, Rand M, Tian, Boxue, Mullins, R. Dyche, Jacobson, Matthew P, Taunton, Jack

“…Electrophilic probes that covalently modify a cysteine thiol often show enhanced pharmacological potency and selectivity. Although reversible Michael acceptors…”
Get full text

WASP and SCAR are evolutionarily conserved in actin-filled pseudopod-based motility by Fritz-Laylin, Lillian K, Lord, Samuel J, Mullins, R Dyche

“…Diverse eukaryotic cells crawl through complex environments using distinct modes of migration. To understand the underlying mechanisms and their evolutionary…”
Get full text

Initiation and disassembly of filopodia tip complexes containing VASP and lamellipodin by Cheng, Karen W., Mullins, R. Dyche

“…Clustering of the actin polymerase VASP (vasodilator-stimulated phosphoprotein) reorganizes leading-edge actin filaments into filopodia bundles in crawling…”
Get full text

Does Providence Entail Divine Temporality? Maybe by Mullins, R T

“…Within contemporary Christian philosophical theology, there are three broad theories of providence being debated. These are theological determinism, Molinism,…”
Get full text

Structural and molecular changes in the aging choroid: implications for age-related macular degeneration by Chirco, K R, Sohn, E H, Stone, E M, Tucker, B A, Mullins, R F

“…Age-related macular degeneration (AMD) is a devastating disease-causing vision loss in millions of people around the world. In advanced stages of disease,…”
Get full text

Archaeal actins and the origin of a multi-functional cytoskeleton by Charles-Orszag, Arthur, Petek-Seoane, Natalie A, Mullins, R Dyche

“…Actin and actin-like proteins form filamentous polymers that carry out important cellular functions in all domains of life. In this review, we sketch a map of…”
Get full text

Actomyosin dynamics drive local membrane component organization in an in vitro active composite layer by Köster, Darius Vasco, Husain, Kabir, Iljazi, Elda, Bhat, Abrar, Bieling, Peter, Mullins, R. Dyche, Rao, Madan, Mayor, Satyajit

“…The surface of a living cell provides a platform for receptor signaling, protein sorting, transport, and endocytosis, whose regulation requires the local…”
Get full text

Actin-based protrusions of migrating neutrophils are intrinsically lamellar and facilitate direction changes by Fritz-Laylin, Lillian K, Riel-Mehan, Megan, Chen, Bi-Chang, Lord, Samuel J, Goddard, Thomas D, Ferrin, Thomas E, Nicholson-Dykstra, Susan M, Higgs, Henry, Johnson, Graham T, Betzig, Eric, Mullins, R Dyche

“…Leukocytes and other amoeboid cells change shape as they move, forming highly dynamic, actin-filled pseudopods. Although we understand much about the…”
Get full text

The Difficulty with Demarcating Panentheism by Mullins, R. T.

“…In certain theological circles today, panentheism is all the rage. One of the most notorious difficulties with panentheism lies in figuring out what…”
Get full text

The Creator/Creature Distinction in Debates over Models of God by Mullins, R. T

“…In contemporary theology, one can find an array of models of God to choose from. There are various types of arguments that one can put forth in order to reject…”
Get full text