Search Results - "Mulligan, Vikram K"

Global analysis of protein folding using massively parallel design, synthesis, and testing by Rocklin, Gabriel J., Chidyausiku, Tamuka M., Goreshnik, Inna, Ford, Alex, Houliston, Scott, Lemak, Alexander, Carter, Lauren, Ravichandran, Rashmi, Mulligan, Vikram K., Chevalier, Aaron, Arrowsmith, Cheryl H., Baker, David

“…Proteins fold into unique native structures stabilized by thousands of weak interactions that collectively overcome the entropic cost of folding. Although…”
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The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design by Alford, Rebecca F, Leaver-Fay, Andrew, Jeliazkov, Jeliazko R, O’Meara, Matthew J, DiMaio, Frank P, Park, Hahnbeom, Shapovalov, Maxim V, Renfrew, P. Douglas, Mulligan, Vikram K, Kappel, Kalli, Labonte, Jason W, Pacella, Michael S, Bonneau, Richard, Bradley, Philip, Dunbrack, Roland L, Das, Rhiju, Baker, David, Kuhlman, Brian, Kortemme, Tanja, Gray, Jeffrey J

“…Over the past decade, the Rosetta biomolecular modeling suite has informed diverse biological questions and engineering challenges ranging from interpretation…”
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The emerging role of computational design in peptide macrocycle drug discovery by Mulligan, Vikram K

“…Drug discovery is a laborious process with rising cost per new drug. Peptide macrocycles are promising therapeutics, though conformational flexibility can…”
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A computational method for the design of nested proteins by loop‐directed domain insertion by Blacklock, Kristin M., Yang, Lu, Mulligan, Vikram K., Khare, Sagar D.

“…The computational design of novel nested proteins—in which the primary structure of one protein domain (insert) is flanked by the primary structure segments of…”
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Correction to “The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design” by Alford, Rebecca F., Leaver-Fay, Andrew, Jeliazkov, Jeliazko R., O’Meara, Matthew J., DiMaio, Frank P., Park, Hahnbeom, Shapovalov, Maxim V., Renfrew, P. Douglas, Mulligan, Vikram K., Kappel, Kalli, Labonte, Jason W., Pacella, Michael S., Bonneau, Richard, Bradley, Philip, Dunbrack, Roland L., Das, Rhiju, Baker, David, Kuhlman, Brian, Kortemme, Tanja, Gray, Jeffrey J.

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Drosophila melanogaster Cad99C, the orthologue of human Usher cadherin PCDH15, regulates the length of microvilli by D'Alterio, Cecilia, Tran, Dao D.D, Yeung, Maggie W.Y. Au, Hwang, Michael S.H, Li, Michelle A, Arana, Claudia J, Mulligan, Vikram K, Kubesh, Mary, Sharma, Praveer, Chase, Maretta, Tepass, Ulrich, Godt, Dorothea

“…Actin-based protrusions can form prominent structures on the apical surface of epithelial cells, such as microvilli. Several cytoplasmic factors have been…”
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Programmable design of orthogonal protein heterodimers by Chen, Zibo, Boyken, Scott E., Jia, Mengxuan, Busch, Florian, Flores-Solis, David, Bick, Matthew J., Lu, Peilong, VanAernum, Zachary L., Sahasrabuddhe, Aniruddha, Langan, Robert A., Bermeo, Sherry, Brunette, T. J., Mulligan, Vikram Khipple, Carter, Lauren P., DiMaio, Frank, Sgourakis, Nikolaos G., Wysocki, Vicki H., Baker, David

“…Specificity of interactions between two DNA strands, or between protein and DNA, is often achieved by varying bases or side chains coming off the DNA or…”
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Concentration-Dependent Structural Transitions of Human Telomeric DNA Sequences by Macgregor, Robert, Abu-Ghazalah, Rashid, Rutledge, Steve, Lau, Lewis W.Y., Tsai, Tiffanie, Mulligan, Vikram K., Chakrabartty, Avi, Helmy, Amr S.

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Multibody molecular docking on a quantum annealer by Pandey, Mohit, Zaborniak, Tristan, Melo, Hans, Galda, Alexey, Mulligan, Vikram K

“…Molecular docking, which aims to find the most stable interacting configuration of a set of molecules, is of critical importance to drug discovery. Although a…”
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Correction: Drosophila melanogaster Cad99C, the orthologue of human Usher cadherin PCDH15, regulates the length of microvilli by D'Alterio, Cecilia, Tran, Dao D.D., Yeung, Maggie W.Y. Au, Hwang, Michael S.H., Li, Michelle A., Arana, Claudia J., Mulligan, Vikram K., Kubesh, Mary, Sharma, Praveer, Chase, Maretta, Tepass, Ulrich, Godt, Dorothea

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Correction by D'Alterio, Cecilia, Tran, Dao D.D., Yeung, Maggie W.Y. Au, Hwang, Michael S.H., Li, Michelle A., Arana, Claudia J., Mulligan, Vikram K., Kubesh, Mary, Sharma, Praveer, Chase, Maretta, Tepass, Ulrich, Godt, Dorothea

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Drosophila melonogaster Cad99C, the Orthologue of Human Usher Cadherin PCDH15, Regulates the Length of Microvilli by D'Alterio, Cecilia, Dao D. D. Tran, Maggie W. Y. Au Yeung, Michael S. H. Hwang, Li, Michelle A., Arana, Claudia J., Mulligan, Vikram K., Kubesh, Mary, Sharma, Praveer, Chase, Maretta, Tepass, Ulrich, Godt, Dorothea

“…Actin-based protrusions can form prominent structures on the apical surface of epithelial cells, such as microvilli. Several cytoplasmic factors have been…”
Get full text