Search Results - "Mulligan, G."

Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma by Chng, W-J, Huang, G F, Chung, T H, Ng, S B, Gonzalez-Paz, N, Troska-Price, T, Mulligan, G, Chesi, M, Bergsagel, P L, Fonseca, R

“…Events mediating transformation from the pre-malignant monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM) are unknown. We…”
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A gene expression signature for high-risk multiple myeloma by Kuiper, R, Broyl, A, de Knegt, Y, van Vliet, M H, van Beers, E H, van der Holt, B, el Jarari, L, Mulligan, G, Gregory, W, Morgan, G, Goldschmidt, H, Lokhorst, H M, van Duin, M, Sonneveld, P

“…There is a strong need to better predict the survival of patients with newly diagnosed multiple myeloma (MM). As gene expression profiles (GEPs) reflect the…”
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RPL5 on 1p22.1 is recurrently deleted in multiple myeloma and its expression is linked to bortezomib response by Hofman, I J F, van Duin, M, De Bruyne, E, Fancello, L, Mulligan, G, Geerdens, E, Garelli, E, Mancini, C, Lemmens, H, Delforge, M, Vandenberghe, P, Wlodarska, I, Aspesi, A, Michaux, L, Vanderkerken, K, Sonneveld, P, De Keersmaecker, K

“…Chromosomal region 1p22 is deleted in ⩾20% of multiple myeloma (MM) patients, suggesting the presence of an unidentified tumor suppressor. Using…”
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Cancer testis antigens in newly diagnosed and relapse multiple myeloma: prognostic markers and potential targets for immunotherapy by VAN DUIN, Mark, BROYL, Annemiek, SAHOTA, Surinder S, SONNEVELD, Pieter, DE KNEGT, Yvonne, GOLDSCHMIDT, Hartmut, RICHARDSON, Paul G, HOP, Wim C. J, VAN DER HOLT, Bronno, JOSEPH-PIETRAS, Debora, MULLIGAN, George, NEUWIRTH, Rachel

“…In multiple myeloma, expression of cancer testis antigens may provide prognostic markers and potential targets for immunotherapy. Expression at relapse has not…”
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Exercise-Associated Hyponatremia, Renal Function, and Nonsteroidal Antiinflammatory Drug Use in an Ultraendurance Mountain Run by Page, A J, Reid, S A, Speedy, D B, Mulligan, G P, Thompson, J

“…OBJECTIVE:To study biochemical parameters and renal function in runners completing a 60 km mountain run and to investigate the incidence of exercise-associated…”
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A gene expression signature for high-risk multiple myeloma by Kuiper, R, Broyl, A, de Knegt, Y, van Vliet, M H, van Beers, E H, van der Holt, B, el Jarari, L, Mulligan, G, Gregory, W, Morgan, G, Goldschmidt, H, Lokhorst, H M, van Duin, M, Sonneveld, P

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Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization by Sage, J, Mulligan, G J, Attardi, L D, Miller, A, Chen, S, Williams, B, Theodorou, E, Jacks, T

“…The retinoblastoma protein, pRB, and the closely related proteins p107 and p130 are important regulators of the mammalian cell cycle. Biochemical and genetic…”
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227 Association of K-Ras Genotype with Xenograft Tumor Response to the Investigational Proteasome Inhibitor MLN9708 by Chattopadhyay, N, DiBacco, A, Garnsey, J, Bannerman, B, Hales, P, Yu, J, Mulligan, G, Koenig, E, Berger, A, Manfredi, M

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A subset of p53 -deficient embryos exhibit exencephaly by Sah, Valerie P, Attardi, Laura D, Mulligan, George J, Williams, Bart O, Bronson, Roderick T, Jacks, Tyler

“…Defects in neural tube formation are among the most common malformations leading to infant mortality. Although numerous genetic loci appear to contribute to…”
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Literature Lab: a method of automated literature interrogation to infer biology from microarray analysis by Febbo, Phillip G, Mulligan, Mike G, Slonina, David A, Stegmaier, Kimberly, Di Vizio, Dolores, Martinez, Paul R, Loda, Massimo, Taylor, Stephen C

“…The biomedical literature is a rich source of associative information but too vast for complete manual review. We have developed an automated method of…”
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Shared role of the pRB-related p130 and p107 proteins in limb development by Cobrinik, D, Lee, M H, Hannon, G, Mulligan, G, Bronson, R T, Dyson, N, Harlow, E, Beach, D, Weinberg, R A, Jacks, T

“…The p130 protein shares extensive sequence similarity with pRB, the product of the retinoblastoma gene, and is a major E2F-associated protein in quiescent…”
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Targeted disruption of p107: functional overlap between p107 and Rb by Lee, M H, Williams, B O, Mulligan, G, Mukai, S, Bronson, R T, Dyson, N, Harlow, E, Jacks, T

“…To explore the physiological role of p107, a member of retinoblastoma gene (Rb) family, we disrupted the mouse gene by homologous recombination in embryonic…”
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AACR Cancer Progress Report 2016 by Davidson, Nancy E, Armstrong, Scott A, Coussens, Lisa M, Cruz-Correa, Marcia R, DeBerardinis, Ralph J, Doroshow, James H, Foti, Margaret, Hwu, Patrick, Kensler, Thomas W, Morrow, Monica, Mulligan, Charles G, Pao, William, Platz, Elizabeth A, Smith, Thomas J, Willman, Cheryl L

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Did Corliss Steam Engines Fuel Urban Growth in the Late Nineteenth Century? Less Sanguine Results by ABRAMS, BURTON A., LI, JING, MULLIGAN, JAMES G.

“…There is general agreement that the steam engine's rise in importance occurred at the same time as growing urbanization, but considerable disagreement…”
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Market Segmentation and the Diffusion of Quality-Enhancing Innovations: The Case of Downhill Skiing by Mulligan, James G., Llinares, Emmanuel

“…We report econometric results concerning the diffusion of detachable chairlifts in the United States that provide the first empirical evidence that the…”
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Analysis of algorithms for velocity estimation from discrete position versus time data by Brown, R.H., Schneider, S.C., Mulligan, M.G.

“…Algorithms for constructing velocity approximations from discrete position versus time data are investigated. The study is limited to algorithms suitable to…”
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Fathering over Time: What Makes the Difference? by Aldous, Joan, Mulligan, Gail M., Bjarnason, Thoroddur

“…This article examines how much fathers participate in child care, an important component of domestic duties, and factors related to it. It has the advantage of…”
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Initial Diagnostics of a Regional Adjustment Model by Mulligan, G F, Vias, A C, Glavac, S M

“…Adjustment models are used increasingly to analyze population and employment changes in regional economies. However, questions remain about the most…”
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Polypyrimidine tract binding protein interacts with sequences involved in alternative splicing of beta-tropomyosin pre-mRNA by MULLIGAN, G. J, WEI GUO, WORMSLEY, S, HELFMAN, D. M

“…Previous studies of alternative splicing of the rat beta-tropomyosin gene have shown that nonmuscle cells contain factors that block the use of the skeletal…”
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Diffusion of steam-powered firefighting equipment in the United States: innovation adoption at the municipal level by Falaris, Evangelos M., Mulligan, James G., Abrams, Burton A.

“…To date, econometrics-based diffusion studies have focused almost exclusively on the timing of adoption of new technology by firms and individuals. While there…”
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