Search Results - "Muller, Ulrike"
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Click Chemistry-mediated Biotinylation Reveals a Function for the Protease BACE1 in Modulating the Neuronal Surface Glycoproteome
Published in Molecular & cellular proteomics (01-08-2018)“…The cell surface proteome is dynamic and has fundamental roles in cell signaling. Many surface membrane proteins are proteolytically released into a cell's…”
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Amyloid Precursor Protein Protects Neuronal Network Function after Hypoxia via Control of Voltage-Gated Calcium Channels
Published in The Journal of neuroscience (10-08-2016)“…Acute cerebral ischemia and chronic neurovascular diseases share various common mechanisms with neurodegenerative diseases, such as disturbed cellular calcium…”
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Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectors
Published in Nature methods (01-11-2010)“…A targeting method for lentiviral vectors relying on the use of single-chain antibodies recognizing cell-surface antigens is applied to generate lentiviral…”
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Far Away So Close: Race, Whiteness, and German Identity
Published in Identities (Yverdon, Switzerland) (01-12-2011)“…Race and nation have been difficult concepts in Germany since the Holocaust. Although race has seemingly disappeared from public discourse, the concept is very…”
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Amyloid precursor protein knockout diminishes synaptic vesicle proteins at the presynaptic active zone in mouse brain
Published in Current Alzheimer research (01-12-2014)“…The amyloid precursor protein (APP) has previously been allocated to an organellar pool residing in the Golgi apparatus and in endosomal compartments, and in…”
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Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis
Published in Nature (London) (11-08-2016)“…Human and murine tumour cells induce programmed necrosis (necroptosis) of endothelial cells, which promotes tumour cell extravasation and metastasis. Tumour…”
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Not just amyloid: physiological functions of the amyloid precursor protein family
Published in Nature reviews. Neuroscience (01-05-2017)“…Key Points Amyloid precursor protein (APP) and the APP-like proteins APLP1 and APLP2 form the mammalian APP gene family. They have important physiological…”
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The calculated voyage: benchmarking optimal strategies and consumptions in the Japanese eel’s spawning migration
Published in Scientific reports (31-10-2024)“…Eels migrate along largely unknown routes to their spawning ground. By coupling Zermelo’s navigation solution and data from the Japan Coastal Ocean…”
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Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein
Published in Nature communications (31-05-2024)“…Pathologic α-synuclein (α-syn) spreads from cell-to-cell, in part, through binding to the lymphocyte-activation gene 3 (Lag3). Here we report that amyloid β…”
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Penetration of Moxifloxacin into Healthy and Inflamed Subcutaneous Adipose Tissues in Humans
Published in Antimicrobial Agents and Chemotherapy (01-10-2003)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Author Correction: Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein
Published in Nature communications (30-07-2024)Get full text
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Dysregulated ADAM10-Mediated Processing of APP during a Critical Time Window Leads to Synaptic Deficits in Fragile X Syndrome
Published in Neuron (Cambridge, Mass.) (15-07-2015)“…The Fragile X mental retardation protein (FMRP) regulates neuronal RNA metabolism, and its absence or mutations leads to the Fragile X syndrome (FXS). The…”
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Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function
Published in eLife (23-01-2016)“…Metzincin metalloproteases have major roles in intercellular communication by modulating the function of membrane proteins. One of the proteases is the…”
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How the body contributes to the wake in undulatory fish swimming: flow fields of a swimming eel (Anguilla anguilla)
Published in Journal of experimental biology (01-08-2001)“…Undulatory swimmers generate thrust by passing a transverse wave down their body. Thrust is generated not just at the tail, but also to a varying degree by the…”
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Complexity and diversity of motion amplification and control strategies in motile carnivorous plant traps
Published in Proceedings of the Royal Society. B, Biological sciences (26-05-2021)“…Similar to animals, plants have evolved mechanisms for elastic energy storage and release to power and control rapid motion, yet both groups have been largely…”
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Viral gene transfer of APPsα rescues synaptic failure in an Alzheimer’s disease mouse model
Published in Acta neuropathologica (01-02-2016)“…Alzheimer’s disease (AD) is characterized by synaptic failure, dendritic and axonal atrophy, neuronal death and progressive loss of cognitive functions. It is…”
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Presenilin-mediated cleavage of APP regulates synaptotagmin-7 and presynaptic plasticity
Published in Nature communications (14-11-2018)“…Mutations of the intramembrane protease presenilin (PS) or of its main substrate, the amyloid precursor protein (APP), cause early-onset form of Alzheimer…”
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