Search Results - "Mullen, William"

Recent advances in capillary electrophoresis coupled to mass spectrometry for clinical proteomic applications by Stalmach, Angelique, Albalat, Amaya, Mullen, William, Mischak, Harald

“…Proteome analysis using capillary electrophoresis coupled to mass spectrometry (CE‐MS) has been used in a number of clinical applications in the past years…”
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Metabolite Profiling of Hydroxycinnamate Derivatives in Plasma and Urine after the Ingestion of Coffee by Humans: Identification of Biomarkers of Coffee Consumption by STALMACH, Angélique, MULLEN, William, BARRON, Denis, UCHIDA, Kenichi, YOKOTA, Takao, CAVIN, Christophe, STEILING, Heike, WILLIAMSON, Gary, CROZIER, Alan

“…Human subjects drank coffee containing 412 μmol of chlorogenic acids, and plasma and urine were collected 0 to 24 h after ingestion and were analyzed by…”
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Diagnosis and Prediction of CKD Progression by Assessment of Urinary Peptides by Schanstra, Joost P, Zürbig, Petra, Alkhalaf, Alaa, Argiles, Angel, Bakker, Stephan J L, Beige, Joachim, Bilo, Henk J G, Chatzikyrkou, Christos, Dakna, Mohammed, Dawson, Jesse, Delles, Christian, Haller, Hermann, Haubitz, Marion, Husi, Holger, Jankowski, Joachim, Jerums, George, Kleefstra, Nanne, Kuznetsova, Tatiana, Maahs, David M, Menne, Jan, Mullen, William, Ortiz, Alberto, Persson, Frederik, Rossing, Peter, Ruggenenti, Piero, Rychlik, Ivan, Serra, Andreas L, Siwy, Justyna, Snell-Bergeon, Janet, Spasovski, Goce, Staessen, Jan A, Vlahou, Antonia, Mischak, Harald, Vanholder, Raymond

“…Progressive CKD is generally detected at a late stage by a sustained decline in eGFR and/or the presence of significant albuminuria. With the aim of early and…”
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Comparative Analysis of Label-Free and 8-Plex iTRAQ Approach for Quantitative Tissue Proteomic Analysis by Latosinska, Agnieszka, Vougas, Konstantinos, Makridakis, Manousos, Klein, Julie, Mullen, William, Abbas, Mahmoud, Stravodimos, Konstantinos, Katafigiotis, Ioannis, Merseburger, Axel S, Zoidakis, Jerome, Mischak, Harald, Vlahou, Antonia, Jankowski, Vera

“…High resolution proteomics approaches have been successfully utilized for the comprehensive characterization of the cell proteome. However, in the case of…”
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Non-invasive FFRCT revealing severe inducible ischaemia in an anomalous right coronary artery by Zimmermann, Frederik Maria, Kobayashi, Yuhei, Mullen, William L, Fearon, William Fuller

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Absorption, excretion and metabolite profiling of methyl-, glucuronyl-, glucosyl- and sulpho-conjugates of quercetin in human plasma and urine after ingestion of onions by Mullen, William, Edwards, Christine A., Crozier, Alan

“…It is essential to have a thorough knowledge of the bioavailability and metabolism of dietary flavonols to understand their role in disease prevention. Lightly…”
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Development and Validation of Urine-based Peptide Biomarker Panels for Detecting Bladder Cancer in a Multi-center Study by Frantzi, Maria, van Kessel, Kim E, Zwarthoff, Ellen C, Marquez, Mirari, Rava, Marta, Malats, Núria, Merseburger, Axel S, Katafigiotis, Ioannis, Stravodimos, Konstantinos, Mullen, William, Zoidakis, Jerome, Makridakis, Manousos, Pejchinovski, Martin, Critselis, Elena, Lichtinghagen, Ralph, Brand, Korbinian, Dakna, Mohammed, Roubelakis, Maria G, Theodorescu, Dan, Vlahou, Antonia, Mischak, Harald, Anagnou, Nicholas P

“…Urothelial bladder cancer presents high recurrence rates, mandating continuous monitoring via invasive cystoscopy. The development of noninvasive tests for…”
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Green Tea Flavan-3-ols: Colonic Degradation and Urinary Excretion of Catabolites by Humans by Roowi, Suri, Stalmach, Angelique, Mullen, William, Lean, Michael E. J, Edwards, Christine A, Crozier, Alan

“…Following the ingestion of green tea, substantial quantities of flavan-3-ols pass from the small to the large intestine (Stalmach et al. Mol. Nutr. Food Res…”
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Assessment of metabolomic and proteomic biomarkers in detection and prognosis of progression of renal function in chronic kidney disease by Nkuipou-Kenfack, Esther, Duranton, Flore, Gayrard, Nathalie, Argilés, Àngel, Lundin, Ulrika, Weinberger, Klaus M, Dakna, Mohammed, Delles, Christian, Mullen, William, Husi, Holger, Klein, Julie, Koeck, Thomas, Zürbig, Petra, Mischak, Harald

“…Chronic kidney disease (CKD) is part of a number of systemic and renal diseases and may reach epidemic proportions over the next decade. Efforts have been made…”
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Urinary proteomics to support diagnosis of stroke by Dawson, Jesse, Walters, Matthew, Delles, Christian, Mischak, Harald, Mullen, William

“…Accurate diagnosis in suspected ischaemic stroke can be difficult. We explored the urinary proteome in patients with stroke (n = 69), compared to controls (n =…”
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Comparison of Depletion Strategies for the Enrichment of Low-Abundance Proteins in Urine by Filip, Szymon, Vougas, Konstantinos, Zoidakis, Jerome, Latosinska, Agnieszka, Mullen, William, Spasovski, Goce, Mischak, Harald, Vlahou, Antonia, Jankowski, Joachim

“…Proteome analysis of complex biological samples for biomarker identification remains challenging, among others due to the extended range of protein…”
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Dietary Fibres Differentially Impact on the Production of Phenolic Acids from Rutin in an In Vitro Fermentation Model of the Human Gut Microbiota by Havlik, Jaroslav, Marinello, Vittoria, Gardyne, Andrew, Hou, Min, Mullen, William, Morrison, Douglas J, Preston, Thomas, Combet, Emilie, Edwards, Christine A

“…Polyphenols are often ingested alongside dietary fibres. They are both catabolised by, and may influence, the intestinal microbiota; yet, interactions between…”
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Proteomics of vitreous humor of patients with exudative age-related macular degeneration by Koss, Michael Janusz, Hoffmann, Janosch, Nguyen, Nauke, Pfister, Marcel, Mischak, Harald, Mullen, William, Husi, Holger, Rejdak, Robert, Koch, Frank, Jankowski, Joachim, Krueger, Katharina, Bertelmann, Thomas, Klein, Julie, Schanstra, Joost P, Siwy, Justyna

“…There is absence of specific biomarkers and an incomplete understanding of the pathophysiology of exudative age-related macular degeneration (AMD)…”
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Urinary proteomics can define distinct diagnostic inflammatory arthritis subgroups by Siebert, Stefan, Porter, Duncan, Paterson, Caron, Hampson, Rosie, Gaya, Daniel, Latosinska, Agnieszka, Mischak, Harald, Schanstra, Joost, Mullen, William, McInnes, Iain

“…Current diagnostic tests applied to inflammatory arthritis lack the necessary specificity to appropriately categorise patients. There is a need for novel…”
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The introduction of a novel formulation of buprenorphine into organized health systems by Mullen, William, Hedberg, Michaela, Gadbois, Brian, Heidbreder, Christian

“…•Real-world data analysis of opioid use disorder treatment distribution.•Buprenorphine extended-release increased in organized health systems.•Distribution…”
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Polymerization-Incompetent Uromodulin in the Pregnant Stroke-Prone Spontaneously Hypertensive Rat by Mary, Sheon, Small, Heather Yvonne, Siwy, Justyna, Mullen, William, Giri, Ashok, Delles, Christian

“…The kidney is centrally involved in blood pressure regulation and undergoes extensive changes during pregnancy. Hypertension during pregnancy may result in an…”
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Potassium deficiency induces the biosynthesis of oxylipins and glucosinolates in Arabidopsis thaliana by Troufflard, Stephanie, Mullen, William, Larson, Tony R, Graham, Ian A, Crozier, Alan, Amtmann, Anna, Armengaud, Patrick

“…Mineral fertilization and pest control are essential and costly requirements for modern crop production. The two measures go hand in hand because plant mineral…”
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Peptide fingerprinting of Alzheimer's disease in cerebrospinal fluid: identification and prospective evaluation of new synaptic biomarkers by Jahn, Holger, Wittke, Stefan, Zürbig, Petra, Raedler, Thomas J, Arlt, Sönke, Kellmann, Markus, Mullen, William, Eichenlaub, Martin, Mischak, Harald, Wiedemann, Klaus

“…Today, dementias are diagnosed late in the course of disease. Future treatments have to start earlier in the disease process to avoid disability requiring new…”
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Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability by Williams, Jamie J. L., Alotaiq, Nasser, Mullen, William, Burchmore, Richard, Liu, Libin, Baillie, George S., Schaper, Fred, Pilch, Paul F., Palmer, Timothy M.

“…Effective suppression of JAK–STAT signalling by the inducible inhibitor “suppressor of cytokine signalling 3” (SOCS3) is essential for limiting signalling from…”
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Mitogen-Activated Protein Kinase 14 Promotes AKI by Ortiz, Alberto, Husi, Holger, Gonzalez-Lafuente, Laura, Valiño-Rivas, Lara, Fresno, Manuel, Sanz, Ana Belen, Mullen, William, Albalat, Amaya, Mezzano, Sergio, Vlahou, Tonia, Mischak, Harald, Sanchez-Niño, Maria Dolores

“…An improved understanding of pathogenic pathways in AKI may identify novel therapeutic approaches. Previously, we conducted unbiased liquid…”
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