Search Results - "Mullen, Rachel"

AMH and AMHR2 mutations: A spectrum of reproductive phenotypes across vertebrate species by Mullen, Rachel D., Ontiveros, Alejandra E., Moses, Malcolm M., Behringer, Richard R.

“…Anti-Müllerian hormone (AMH) is a member of the Transforming Growth Factor-β family of secreted signaling proteins. AMH is expressed in Sertoli cells of the…”
Get full text

Molecular genetics of Müllerian duct formation, regression and differentiation by Mullen, Rachel D, Behringer, Richard R

“…The Müllerian duct (MD) forms the female reproductive tract (FRT) consisting of the oviducts, uterus, cervix, and upper vagina. FRT function is vital to…”
Get more information

Distal-less homeobox genes Dlx5/6 regulate Müllerian duct regression by Mullen, Rachel D., Bellessort, Brice, Levi, Giovanni, Behringer, Richard R.

“…Dlx5 and Dlx6 encode distal-less homeodomain transcription factors that are present in the genome as a linked pair at a single locus. Dlx5 and Dlx6 have…”
Get full text

Osterix functions downstream of anti-Müllerian hormone signaling to regulate Müllerian duct regression by Mullen, Rachel D., Wang, Ying, Liu, Bin, Moore, Emma L., Behringer, Richard R.

“…In mammals, the developing reproductive tract primordium of male and female fetuses consists of the Wolffian duct and the Müllerian duct (MD), two epithelial…”
Get full text

Assessing uptake of antimicrobials by Zea mays L. and prevalence of antimicrobial resistance genes in manure-fertilized soil by Mullen, Rachel A., Hurst, Jerod J., Naas, Kayla M., Sassoubre, Lauren M., Aga, Diana S.

“…Manure-borne antimicrobials and antimicrobial resistance genes (ARGs) are of environmental concern due to their potential to be transferred into the food-web…”
Get full text

Chronic Estrus Disrupts Uterine Gland Development and Homeostasis by Stewart, C Allison, Stewart, M David, Wang, Ying, Mullen, Rachel D, Kircher, Bonnie K, Liang, Rui, Liu, Yu, Behringer, Richard R

“…Female mice homozygous for an engineered Gnrhr E90K mutation have reduced gonadotropin-releasing hormone signaling, leading to infertility. Their ovaries have…”
Get full text

CreLite: An optogenetically controlled Cre/loxP system using red light by Yen, Shuo‐Ting, Trimmer, Kenneth A., Aboul‐Fettouh, Nader, Mullen, Rachel D., Culver, James C., Dickinson, Mary E., Behringer, Richard R., Eisenhoffer, George T.

“…Background Precise manipulation of gene expression with temporal and spatial control is essential for functional analysis and determining cell lineage…”
Get full text

Loss of LPAR6 and CAB39L dysregulates the basal-to-luminal urothelial differentiation program, contributing to bladder carcinogenesis by Lee, Sangkyou, Bondaruk, Jolanta, Wang, Yishan, Chen, Huiqin, Lee, June Goo, Majewski, Tadeusz, Mullen, Rachel D., Cogdell, David, Chen, Jiansong, Wang, Ziqiao, Yao, Hui, Kus, Pawel, Jeong, Joon, Lee, Ilkyun, Choi, Woonyoung, Navai, Neema, Guo, Charles, Dinney, Colin, Baggerly, Keith, Mendelsohn, Cathy, McConkey, David, Behringer, Richard R., Kimmel, Marek, Wei, Peng, Czerniak, Bogdan

“…We describe a strategy that combines histologic and molecular mapping that permits interrogation of the chronology of changes associated with cancer…”
Get full text

Patient experiences of their current asthma care and their views toward providing support for patients with asthma in community pharmacy: A Qualitative study by Mahmoud, Aseel, Mullen, Rachel, Penson, Peter E., Morecroft, Charles

“…An estimated 300 million people live with asthma globally. In England, a significant percentage live with poorly controlled asthma symptoms. Community…”
Get full text

Cell-Specific Actions of a Human LHX3 Gene Enhancer During Pituitary and Spinal Cord Development by Park, Soyoung, Mullen, Rachel D, Rhodes, Simon J

“…The LIM class of homeodomain protein 3 (LHX3) transcription factor is essential for pituitary gland and nervous system development in mammals. In humans,…”
Get full text

Assessment of asthma management in adult patients: A retrospective case-note review in a general practice by Mahmoud, Aseel, Mullen, Rachel, Penson, Peter, Morecroft, Charles

“…This study aimed to assessasthma management in a sample of adult patients in general practice. A retrospective case-note review was conducted,involving 27…”
Get full text

A transgenic bacterial artificial chromosome approach to identify regulatory regions that direct Amhr2 and Osterix expression in Müllerian duct mesenchyme by Moses, Malcolm M, Mullen, Rachel D, Idowu, Daniel I, Maye, Peter, Jamin, Soazik P, Behringer, Richard R

“…A transgenic mouse approach using bacterial artificial chromosomes (BAC) was used to identify regulatory regions that direct Müllerian duct expression for and…”
Get full text

A Distal Modular Enhancer Complex Acts to Control Pituitary- and Nervous System-Specific Expression of the LHX3 Regulatory Gene by Mullen, Rachel D, Park, Soyoung, Rhodes, Simon J

“…Lin-11, Isl-1, and Mec-3 (LIM)-homeodomain (HD)-class transcription factors are critical for many aspects of mammalian organogenesis. Of these, LHX3 is…”
Get full text

Three Novel Missense Mutations within the LHX4 Gene Are Associated with Variable Pituitary Hormone Deficiencies by Pfaeffle, Roland W., Hunter, Chad S., Savage, Jesse J., Duran-Prado, Mario, Mullen, Rachel D., Neeb, Zachary P., Eiholzer, Urs, Hesse, Volker, Haddad, Nadine G., Stobbe, Heike M., Blum, Werner F., Weigel, Johannes F. W., Rhodes, Simon J.

“…Context: The LHX4 LIM-homeodomain transcription factor has essential roles in pituitary gland and nervous system development. Heterozygous mutations in LHX4…”
Get full text

Roles of the LHX3 and LHX4 LIM-homeodomain factors in pituitary development by Mullen, Rachel D., Colvin, Stephanie C., Hunter, Chad S., Savage, Jesse J., Walvoord, Emily C., Bhangoo, Amrit P.S., Ten, Svetlana, Weigel, Johannes, Pfäffle, Roland W., Rhodes, Simon J.

“…The LHX3 and LHX4 LIM-homeodomain transcription factors play essential roles in pituitary gland and nervous system development. Mutations in the genes encoding…”
Get full text

LHX3 and LHX4 transcription factors in pituitary development and disease by Colvin, Stephanie C, Mullen, Rachel D, Pfaeffle, Roland W, Rhodes, Simon J

“…The LHX3 and LHX4 LIM-homeodomain proteins are regulatory transcription factors that play overlapping but distinct functions during the establishment of the…”
Get more information

Transgenic mice expressing LHX3 transcription factor isoforms in the pituitary: Effects on the gonadotrope axis and sex-specific reproductive disease by Savage, Jesse J., Mullen, Rachel D., Sloop, Kyle W., Colvin, Stephanie C., Camper, Sally A., Franklin, Craig L., Rhodes, Simon J.

“…The LHX3 transcription factor plays critical roles in pituitary and nervous system development. Mutations in the human LHX3 gene cause severe hormone…”
Get full text

SP5 Parent-led administration of medicine on the neonatal unit by Murray, Sarah, Paize, Fauzia, Mullen, Rachel, Morecroft, Charles

“…BackgroundMedication administration is a high risk and error prone task for the trained healthcare professional,1 however, there is little emphasis on training…”
Get full text

The management of asthma in adult patients in the community pharmacy setting: Literature review by Mahmoud, Aseel, Mullen, Rachel, Penson, Peter E., Morecroft, Charles

“…Asthma poses a public health concern, with an estimated 235 million people currently living with the condition globally. The provision of evidence-based,…”
Get full text

Assessment of asthma management in adult patients: A retrospective case note review by Aseel Mahmoud, Rachel Mullen, Peer Penson, Charles Morecroft

“…This study aimed to assess asthma management in a sample of adult patients in a general practice. A retrospective case-note review was conducted, involving 27…”
Get full text