Search Results - "Mullen, K D"

Review article: the design of clinical trials in hepatic encephalopathy – an International Society for Hepatic Encephalopathy and Nitrogen Metabolism (ISHEN) consensus statement by Bajaj, J. S., Cordoba, J., Mullen, K. D., Amodio, P., Shawcross, D. L., Butterworth, R. F., Morgan, M. Y.

“…Aliment Pharmacol Ther 2011; 33: 739–747 Summary Background  The clinical classification of hepatic encephalopathy is largely subjective, which has led to…”
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Randomised clinical trial: rifaximin improves health‐related quality of life in cirrhotic patients with hepatic encephalopathy – a double‐blind placebo‐controlled study by Sanyal, A., Younossi, Z. M., Bass, N. M., Mullen, K. D., Poordad, F., Brown, R. S., Vemuru, R. P., Mazen Jamal, M., Huang, S., Merchant, K., Bortey, E., Forbes, W. P.

“…Aliment Pharmacol Ther 2011; 34: 853–861 Summary Background  Hepatic encephalopathy (HE) is a brain disorder that often results from cirrhosis due to viral…”
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Review of the final report of the 1998 Working Party on definition, nomenclature and diagnosis of hepatic encephalopathy by MULLEN, K. D.

“…The heterogeneity and variability of the manifestations of hepatic encephalopathy among patients and in individual patients over time make the condition…”
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Use of tegaserod along with polyethylene glycol electrolyte solution for colonoscopy bowel preparation: a prospective, randomized, double‐blind, placebo‐controlled study by SANAKA, M. R., SUPER, D. M., MULLEN, K. D., FERGUSON, D. R., McCULLOUGH, A. J.

“…Summary Background  Polyethylene glycol electrolyte solution (PEG‐EL) used for colonoscopy preparation is not well tolerated by several patients. A significant…”
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Primary prophylaxis of variceal bleeding in cirrhosis: A cost- effectiveness analysis by Teran, JC, Imperiale, TF, Mullen, KD, Tavill, AS, McCullough, AJ

“…BACKGROUND & AIMS: Prophylaxis against the first variceal bleeding has been proposed to reduce morbidity and mortality in cirrhotic patients. No previous…”
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Hepatic encephalopathy by Ong, J P, Mullen, K D

“…In the last decade, a significant amount of research has been devoted to the pathogenesis and treatment of hepatic encephalopathy (HE). Non-invasive…”
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Thrombotic microangiopathy and cytomegalovirus in liver transplant recipients: a case‐based review by Ramasubbu, K., Mullick, T., Koo, A., Hussein, M., Henderson, J.M., Mullen, K.D., Avery, R.K.

“…: Background. Thrombotic microangiopathy (TMA) is a rare but potentially lethal complication encountered in solid organ and bone marrow transplant recipients,…”
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Completion of upper endoscopic procedures despite paradoxical reaction to midazolam: a role for flumazenil? by Fulton, Scott A, Mullen, Kevin D

“…Paradoxical excitation after benzodiazepine administration is well described. Although it is relatively uncommon, its occurrence can severely impede or even…”
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Randomized, controlled trial of recombinant human alpha-interferon in patients with chronic hepatitis B by Hoofnagle, J H, Peters, M, Mullen, K D, Jones, D B, Rustgi, V, Di Bisceglie, A, Hallahan, C, Park, Y, Meschievitz, C, Jones, E A

“…Forty-five patients with chronic hepatitis B were entered into a randomized controlled trial of recombinant human alpha-interferon therapy. All patients had…”
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Measurements of total body and extracellular water in cirrhotic patients with and without ascites by McCullough, A J, Mullen, K D, Kalhan, S C

“…Using H2[18O] tracer isotope dilution and corrected bromide space as standard reference techniques, we determined total body water and extracellular water in…”
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Benzodiazepines in hepatic encephalopathy: sleeping with the enemy by DASARATHY, S, MULLEN, K D

“…2 Other gut derived compounds have been proposed as possible mediators of hepatic encephalopathy and include gamma amino butyric acid and benzodiazepines. 3…”
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Use of subcutaneous venous access ports to treat refractory ascites by Rosenblum, D I, Geisinger, M A, Newman, J S, Boden, T M, Markowitz, D, Powell, D, Mullen, K D

“…To assess the feasibility of peritoneal ports for management of patients with cirrhotic refractory ascites, 10 ports were placed in nine patients for frequent…”
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Defective nonoxidative leucine degradation and endogenous leucine flux in cirrhosis during an amino acid infusion by McCullough, Arthur J., Mullen, Kevin D., Kalhan, Satish C.

“…The metabolic fate of leucine's first and second carbon may be different depending on the tissue in which leucine is metabolized, as well as the prevailing…”
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Neurological deficits in "awake" cirrhotic patients on hepatic encephalopathy treatment: Missed metabolic or metal disorder? by Mullen, KD, Cole, M, Foley, JM

“…This article has no abstract. To view the article, select the "View Print Version (PDF)" link above…”
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A controlled study of sorbent suspension dialysis in chronic liver disease and hepatic encephalopathy by Kramer, L, Gendo, A, Madl, C, Mullen, K D, Kaminski-Russ, K, Sunder-Plassmann, G, Schaffer, A, Bauer, E, Roth, E, Ferenci, P

“…To investigate the role of extracorporeal detoxification in cirrhotic patients with advanced hepatic encephalopathy not responding to medical treatment, 20…”
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MARS--does it stand the test of time? by Mullen, Kevin D, Dasarathy, Srinivasan

“…Artificial liver support systems have been tested for decades in the management of liver failure. Generally, after some promising results published as case…”
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Glutamine--a conditionally essential amino acid in cirrhosis? by Teran, JC, Mullen, KD, McCullough, AJ

“…Glutamine supplementation in cirrhosis could improve glutamine uptake and oxidation in the intestine. Teran and others suggest that glutamine could be a…”
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"Endogenous" benzodiazepine activity in body fluids of patients with hepatic encephalopathy by Mullen, K D, Szauter, K M, Kaminsky-Russ, K

“…Body fluids from patients with hepatic encephalopathy and from controls with no renal or hepatic disease were assayed for benzodiazepine immunoreactivity and…”
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Differential responsiveness of cerebellar Purkinje neurons to GABA and benzodiazepine receptor ligands in an animal model of hepatic encephalopathy by Basile, AS, Gammal, SH, Mullen, KD, Jones, EA, Skolnick, P

“…The role of the GABA-benzodiazepine receptor complex in the pathogenesis of hepatic encephalopathy was investigated by recording the electrophysiological…”
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A continuous quality improvement initiative reduces inappropriate prescribing of prophylactic antibiotics for endoscopic procedures by O'Connor, Barry J, Sondhi, Satinderpal S, Mullen, Kevin D, McCullough, Arthur J

“…Despite the availability of guidelines, most gastroenterologists do not administer prophylactic antibiotics appropriately to patients having endoscopic…”
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