Search Results - "Mullapudi, Sri Teja"
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A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development
Published in Development (Cambridge) (24-07-2019)“…An early step in pancreas development is marked by the expression of the transcription factor Pdx1 within the pancreatic endoderm, where it is required for the…”
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Thyroid Hormone Coordinates Pancreatic Islet Maturation During the Zebrafish Larval-to-Juvenile Transition to Maintain Glucose Homeostasis
Published in Diabetes (New York, N.Y.) (01-10-2017)“…Thyroid hormone (TH) signaling promotes tissue maturation and adult organ formation. Developmental transitions alter an organism's metabolic requirements, and…”
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Innervation modulates the functional connectivity between pancreatic endocrine cells
Published in eLife (04-04-2022)“…The importance of pancreatic endocrine cell activity modulation by autonomic innervation has been debated. To investigate this question, we established an in…”
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Screening for insulin-independent pathways that modulate glucose homeostasis identifies androgen receptor antagonists
Published in eLife (06-12-2018)“…Pathways modulating glucose homeostasis independently of insulin would open new avenues to combat insulin resistance and diabetes. Here, we report the…”
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Antigenicity and Immunogenicity of a Trimeric Envelope Protein from an Indian Clade C HIV-1 Isolate
Published in The Journal of biological chemistry (03-04-2015)“…Human immunodeficiency virus type 1 (HIV-1) isolates from India mainly belong to clade C and are quite distinct from clade C isolates from Africa in terms of…”
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Artificial intelligence and its contribution to overcome COVID-19
Published in International journal of noncommunicable diseases (01-11-2021)“…Artificial intelligence (AI) has a great impact on our daily living and makes our lives more efficient and productive. Especially during the coronavirus…”
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Mechanical Forces Regulate Cardiomyocyte Myofilament Maturation via the VCL-SSH1-CFL Axis
Published in Developmental cell (07-10-2019)“…Mechanical forces regulate cell behavior and tissue morphogenesis. During cardiac development, mechanical stimuli from the heartbeat are required for…”
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Whole-Organism Chemical Screening Identifies Modulators of Pancreatic β-Cell Function
Published in Diabetes (New York, N.Y.) (01-11-2018)“…β-Cell loss and dysfunction play a critical role in the progression of type 1 and type 2 diabetes. Identifying new molecules and/or molecular pathways that…”
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Disruption of the pancreatic vasculature in zebrafish affects islet architecture and function
Published in Development (Cambridge) (2019)“…A dense local vascular network is crucial for pancreatic endocrine cells to sense metabolites and secrete hormones, and understanding the interactions between…”
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