Search Results - "Mullane, K M"

International, open-label, noncomparative, clinical trial of micafungin alone and in combination for treatment of newly diagnosed and refractory candidemia by OSTROSKY-ZEICHNER, L, KONTOYIANNIS, D, LAU, W, FACKLAM, D, BUELL, D. N, RAFFALLI, J, MULLANE, K. M, VAZQUEZ, J, ANAISSIE, E. J, LIPTON, J, JACOBS, P, VAN RENSBURG, J. H, REX, J. H

“…Candida spp. are the fourth leading cause of bloodstream infections, and non-albicans species are increasing in importance. Micafungin is a new echinocandin…”
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Brincidofovir treatment of acyclovir‐resistant disseminated varicella zoster virus infection in an immunocompromised host by Mullane, K.M., Nuss, C., Ridgeway, J., Prichard, M.N., Hartline, C.B., Theusch, J., Mommeja‐Marin, H., Larson, R.A.

“…Brincidofovir (BCV) is a broad‐spectrum antiviral agent active in vitro against double‐stranded DNA viruses including herpesviruses, adenoviruses,…”
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Letermovir Prophylaxis for Cytomegalovirus in Hematopoietic-Cell Transplantation by Marty, Francisco M, Ljungman, Per, Chemaly, Roy F, Maertens, Johan, Dadwal, Sanjeet S, Duarte, Rafael F, Haider, Shariq, Ullmann, Andrew J, Katayama, Yuta, Brown, Janice, Mullane, Kathleen M, Boeckh, Michael, Blumberg, Emily A, Einsele, Hermann, Snydman, David R, Kanda, Yoshinobu, DiNubile, Mark J, Teal, Valerie L, Wan, Hong, Murata, Yoshihiko, Kartsonis, Nicholas A, Leavitt, Randi Y, Badshah, Cyrus

“…CMV infection is a common complication in patients undergoing hematopoietic-cell transplantation. The incidence of CMV infection was 23 percentage points lower…”
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Role of leukocytes in acute myocardial infarction in anesthetized dogs: relationship to myocardial salvage by anti-inflammatory drugs by Mullane, K M, Read, N, Salmon, J A, Moncada, S

“…The invasion of leukocytes into and around a myocardial infarct was studied in chloralose-anesthetized dogs subjected to 1-hr occlusion of the left anterior…”
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Alleviation of myocardial stunning by leukocyte and platelet depletion by WESTLIN, W, MULLANE, K. M

“…Neutrophils accumulate in myocardium rendered ischemic and reperfused. Activated neutrophils release mediators such as metabolites of oxygen that can…”
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Leukocytes and ischemia-induced myocardial injury by Lucchesi, B R, Mullane, K M

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Protective effect of an adenosine kinase inhibitor in septic shock by Firestein, GS, Boyle, D, Bullough, DA, Gruber, HE, Sajjadi, FG, Montag, A, Sambol, B, Mullane, KM

“…Adenosine exhibits potent anti-inflammatory activities but its therapeutic use is limited by cardiovascular side effects. Inhibitors of an enzyme involved in…”
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Arachidonic acid-induced endothelial-dependent relaxations of canine coronary arteries: contribution of a cytochrome P-450-dependent pathway by Pinto, A, Abraham, N G, Mullane, K M

“…Arachidonic acid (AA, 10(-8)-5 X 10(-6) M) induced dose-dependent relaxations of canine coronary arterial rings precontracted with dinoprost that were…”
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Thromboxane Synthetase Inhibitors Reduce Infarct Size by a Platelet-Dependent, Aspirin-Sensitive Mechanism by Mullane, Kevin M, Fornabaio, Donna

“…Platelets are suggested to exacerbate ischemia-induced myocardial injury, which has led to the study of various antiplatelet therapies including thromboxane…”
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Nafazatrom-Induced Salvage of Ischemic Myocardium in Anesthetized Dogs is Mediated through Inhibition of Neutrophil Function by Bednar, Martin, Smith, Bruce, Pinto, Aldo, Mullane, Kevin M

“…The effects of nafazatrom on leukocyte function in vitro and in vivo were related to its ability to salvage ischemic myocardium in an occlusion-reperfusion…”
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Adenosine activates A2 receptors to inhibit neutrophil adhesion and injury to isolated cardiac myocytes by Bullough, DA, Magill, MJ, Firestein, GS, Mullane, KM

“…Inhibition of neutrophil-myocyte adhesion and adhesion-dependent myocyte injury by adenosine was evaluated using isolated TNF-alpha-activated canine cells…”
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Impaired endothelium-dependent relaxations in rabbits subjected to aortic coarctation hypertension by MILLER, M. J. S, PINTO, A, MULLANE, K. M

“…Rabbits were rendered hypertensive by suprarenal coarctation of the abdominal aorta. Seven days later, endothelium-dependent and endothelium-independent…”
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Reversal of accelerated neutrophil apoptosis and restoration of respiratory burst activity with r-metHuG-CSF (Filgrastim) therapy in patients with AIDS by PITRAK, D. L, SUTTON, S. H, TSAI, H. C, MULLANE, K. M, PAU, A. K

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International, open-label, noncomparative, clinical trial of micafungin alone and in combination for treatment of newly diagnosed and refractory candidemia by Ostrosky-Zeichner, L., Kontoyiannis, D., Raffalli, J., Mullane, K. M., Vazquez, J., Anaissie, E. J., Lipton, J., Jacobs, P., Rensburg, J. H. Jansen, Rex, J. H., Lau, W., Facklam, D., Buell, D. N.

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Acadesine and myocardial protection : studies of time of administration and dose-response relations in the rat by GALIÑANES, M, MULLANE, K. M, BULLOUGH, D, HEARSE, D. J

“…Although there are many factors that might contribute to tissue injury during ischemia and reperfusion, the loss of adenine nucleotides has long been…”
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Cytochrome P-450-dependent monooxygenase activity and endothelial-dependent relaxations induced by arachidonic acid by Pinto, A, Abraham, N G, Mullane, K M

“…The authors have recently identified a cytochrome P-450-dependent monooxygenase in vascular tissue, localized primarily to the endothelium. As this enzyme…”
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Contribution of oxygen-derived free radicals to experimental necrotizing enterocolitis by Clark, DA, Fornabaio, DM, McNeill, H, Mullane, KM, Caravella, SJ, Miller, MJ

“…Oxygen-derived free radicals, particularly superoxide anion, are considered important mediators of intestinal injury induced by ischemia/reperfusion based on…”
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Progressive cardiac dysfunction with repeated pacing-induced ischemia: protection by AICA-riboside by Young, M A, Mullane, K M

“…The effects of repeated episodes of demand-induced ischemia on regional myocardial wall thickening, endocardial electrogram, and regional myocardial blood flow…”
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Neutrophils delay functional recovery of the post-hypoxic heart of the rabbit by Kraemer, R, Mullane, K M

“…A postischemic contractile dysfunction termed myocardial stunning has been described in vivo and is attributed, in part, to the generation of oxygen-derived…”
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Polymorphonuclear leukocytes reduce cardiac function in vitro by release of H2O2 by Kraemer, R, Seligmann, B, Mullane, K M

“…Polymorphonuclear leukocytes (PMNs) have been implicated in postischemic myocardial injury and associated derangements in contractile function. To examine the…”
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