Search Results - "Mulik, Sachin"

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  1. 1

    Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts by Crespo, Ângela C., Mulik, Sachin, Dotiwala, Farokh, Ansara, James A., Sen Santara, Sumit, Ingersoll, Kayleigh, Ovies, Cristian, Junqueira, Caroline, Tilburgs, Tamara, Strominger, Jack L., Lieberman, Judy

    Published in Cell (03-09-2020)
    “…Maternal decidual NK (dNK) cells promote placentation, but how they protect against placental infection while maintaining fetal tolerance is unclear. Here we…”
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    Ornithine-A urea cycle metabolite enhances autophagy and controls Mycobacterium tuberculosis infection by Sivangala Thandi, Ramya, Radhakrishnan, Rajesh Kumar, Tripathi, Deepak, Paidipally, Padmaja, Azad, Abul K, Schlesinger, Larry S, Samten, Buka, Mulik, Sachin, Vankayalapati, Ramakrishna

    Published in Nature communications (15-07-2020)
    “…Macrophages are professional phagocytes known to play a vital role in controlling Mycobacterium tuberculosis (Mtb) infection and disease progression. Here we…”
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  3. 3

    Meeting the Challenge of Controlling Viral Immunopathology by Berber, Engin, Mulik, Sachin, Rouse, Barry T

    “…The mission of this review is to identify immune-damaging participants involved in antiviral immunoinflammatory lesions. We argue these could be targeted and…”
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    Cytotoxic cells kill intracellular bacteria through granulysin-mediated delivery of granzymes by Walch, Michael, Dotiwala, Farokh, Mulik, Sachin, Thiery, Jerome, Kirchhausen, Tomas, Clayberger, Carol, Krensky, Alan M, Martinvalet, Denis, Lieberman, Judy

    Published in Cell (05-06-2014)
    “…When killer lymphocytes recognize infected cells, perforin delivers cytotoxic proteases (granzymes) into the target cell to trigger apoptosis. What happens to…”
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  6. 6

    Controlling viral inflammatory lesions by rebalancing immune response patterns by Mulik, Sachin, Berber, Engin, Sehrawat, Sharvan, Rouse, Barry Tyrrell

    Published in Frontiers in immunology (21-08-2023)
    “…In this review, we discuss a variety of immune modulating approaches that could be used to counteract tissue-damaging viral immunoinflammatory lesions which…”
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  7. 7

    Costimulatory CD226 Signaling Regulates Proliferation of Memory-like NK Cells in Healthy Individuals with Latent Mycobacterium tuberculosis Infection by Murillo, Oscar, Moreira, Josimar Dornelas, Kujur, Weshely, Velasco-Alzate, Karen, Sen Santara, Sumit, Konduru, Nagarjun V., Mulik, Sachin

    “…It is now widely accepted that NK cells can acquire memory, and this makes them more effective to protect against some pathogens. Prior reports indicate…”
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    Memory like NK cells display stem cell like properties after Zika virus infection by Kujur, Weshely, Murillo, Oscar, Adduri, Raju S R, Vankayalapati, Ramakrishna, Konduru, Nagarjun V, Mulik, Sachin

    Published in PLoS pathogens (28-12-2020)
    “…NK cells have been shown to display adaptive traits such as memory formation akin to T and B lymphocytes. Here we show that Zika virus infection induces memory…”
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    Neuroprotectin D1 reduces the severity of herpes simplex virus-induced corneal immunopathology by Rajasagi, Naveen K, Reddy, Pradeep B J, Mulik, Sachin, Gjorstrup, Per, Rouse, Barry T

    “…Neuroprotectin D1 (NPD1) is an anti-inflammatory and proresolving lipid mediator biosynthesized from the omega-3-polyunsaturated fatty acid docosahexaenoic…”
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    Critical role of microRNA-155 in herpes simplex encephalitis by Bhela, Siddheshvar, Mulik, Sachin, Reddy, Pradeep B J, Richardson, Raphael L, Gimenez, Fernanda, Rajasagi, Naveen K, Veiga-Parga, Tamara, Osmand, Alexander P, Rouse, Barry T

    Published in The Journal of immunology (1950) (15-03-2014)
    “…HSV infection of adult humans occasionally results in life-threatening herpes simplex encephalitis (HSE) for reasons that remain to be defined. An animal…”
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  12. 12

    Robo 4 Counteracts Angiogenesis in Herpetic Stromal Keratitis by Gimenez, Fernanda, Mulik, Sachin, Veiga-Parga, Tamara, Bhela, Siddheshvar, Rouse, Barry T

    Published in PloS one (31-12-2015)
    “…The cornea is a complex tissue that must preserve its transparency to maintain optimal vision. However, in some circumstances, damage to the eye can result in…”
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  13. 13

    Galectin-1 reduces the severity of herpes simplex virus-induced ocular immunopathological lesions by Rajasagi, Naveen K, Suryawanshi, Amol, Sehrawat, Sharvan, Reddy, Pradeep B J, Mulik, Sachin, Hirashima, Mitsuomi, Rouse, Barry T

    Published in The Journal of immunology (1950) (01-05-2012)
    “…Stromal keratitis is a chronic immunopathological lesion of the eye caused by HSV-1 infection that can result in blindness. Because the inflammatory lesions…”
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  14. 14

    Ocular neovascularization caused by herpes simplex virus type 1 infection results from breakdown of binding between vascular endothelial growth factor A and its soluble receptor by Suryawanshi, Amol, Mulik, Sachin, Sharma, Shalini, Reddy, Pradeep B J, Sehrawat, Sharvan, Rouse, Barry T

    Published in The Journal of immunology (1950) (15-03-2011)
    “…The normal cornea is transparent, which is essential for normal vision, and although the angiogenic factor vascular endothelial growth factor A (VEGF-A) is…”
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    An Anti-Inflammatory Role of VEGFR2/Src Kinase Inhibitor in Herpes Simplex Virus 1-Induced Immunopathology by SHARMA, Shalini, MULIK, Sachin, KUMAR, Naveen, SURYAWANSHI, Amol, ROUSE, Barry T

    Published in Journal of Virology (01-06-2011)
    “…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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  16. 16

    Influence of galectin-9/Tim-3 interaction on herpes simplex virus-1 latency by Reddy, Pradeep B J, Sehrawat, Sharvan, Suryawanshi, Amol, Rajasagi, Naveen K, Mulik, Sachin, Hirashima, Mitsuomi, Rouse, Barry T

    Published in The Journal of immunology (1950) (01-12-2011)
    “…After HSV-1 infection, CD8(+) T cells accumulate in the trigeminal ganglion (TG) and participate in the maintenance of latency. However, the mechanisms…”
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  17. 17

    TREX1 Knockdown Induces an Interferon Response to HIV that Delays Viral Infection in Humanized Mice by Wheeler, Lee Adam, Trifonova, Radiana T., Vrbanac, Vladimir, Barteneva, Natasha S., Liu, Xing, Bollman, Brooke, Onofrey, Lauren, Mulik, Sachin, Ranjbar, Shahin, Luster, Andrew D., Tager, Andrew M., Lieberman, Judy

    Published in Cell reports (Cambridge) (24-05-2016)
    “…Despite their antiviral effect, the in vivo effect of interferons on HIV transmission is difficult to predict, because interferons also activate and recruit…”
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    TNFRSF25 Agonistic Antibody and Galectin-9 Combination Therapy Controls Herpes Simplex Virus-Induced Immunoinflammatory Lesions by REDDY, Pradeep B. J, SCHREIBER, Taylor H, RAJASAGI, Naveen K, SURYAWANSHI, Amol, MULIK, Sachin, VEIGA-PARGA, Tamara, NIKI, Toshiro, HIRASHIMA, Mitsuomi, PODACK, Eckhard R, ROUSE, Barry T

    Published in Journal of Virology (01-10-2012)
    “…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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  20. 20

    Activation of endothelial roundabout receptor 4 reduces the severity of virus-induced keratitis by Mulik, Sachin, Sharma, Shalini, Suryawanshi, Amol, Veiga-Parga, Tamara, Reddy, Pradeep B J, Rajasagi, Naveen K, Rouse, Barry T

    Published in The Journal of immunology (1950) (15-06-2011)
    “…Antiangiogenic molecules exert a feedback control to restrain pathological angiogenesis, which includes physical binding or inhibition of angiogenic signaling…”
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