Search Results - "Mulik, Sachin"
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Decidual NK Cells Transfer Granulysin to Selectively Kill Bacteria in Trophoblasts
Published in Cell (03-09-2020)“…Maternal decidual NK (dNK) cells promote placentation, but how they protect against placental infection while maintaining fetal tolerance is unclear. Here we…”
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Ornithine-A urea cycle metabolite enhances autophagy and controls Mycobacterium tuberculosis infection
Published in Nature communications (15-07-2020)“…Macrophages are professional phagocytes known to play a vital role in controlling Mycobacterium tuberculosis (Mtb) infection and disease progression. Here we…”
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Meeting the Challenge of Controlling Viral Immunopathology
Published in International journal of molecular sciences (01-04-2024)“…The mission of this review is to identify immune-damaging participants involved in antiviral immunoinflammatory lesions. We argue these could be targeted and…”
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Editorial: NK cells in viral immunology and immunotherapy
Published in Frontiers in Immunology (23-05-2023)Get full text
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Cytotoxic cells kill intracellular bacteria through granulysin-mediated delivery of granzymes
Published in Cell (05-06-2014)“…When killer lymphocytes recognize infected cells, perforin delivers cytotoxic proteases (granzymes) into the target cell to trigger apoptosis. What happens to…”
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Controlling viral inflammatory lesions by rebalancing immune response patterns
Published in Frontiers in immunology (21-08-2023)“…In this review, we discuss a variety of immune modulating approaches that could be used to counteract tissue-damaging viral immunoinflammatory lesions which…”
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Costimulatory CD226 Signaling Regulates Proliferation of Memory-like NK Cells in Healthy Individuals with Latent Mycobacterium tuberculosis Infection
Published in International journal of molecular sciences (01-11-2022)“…It is now widely accepted that NK cells can acquire memory, and this makes them more effective to protect against some pathogens. Prior reports indicate…”
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Retraction Note: Ornithine-A urea cycle metabolite enhances autophagy and controls Mycobacterium tuberculosis infection
Published in Nature communications (18-10-2022)Get full text
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Memory like NK cells display stem cell like properties after Zika virus infection
Published in PLoS pathogens (28-12-2020)“…NK cells have been shown to display adaptive traits such as memory formation akin to T and B lymphocytes. Here we show that Zika virus infection induces memory…”
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Neuroprotectin D1 reduces the severity of herpes simplex virus-induced corneal immunopathology
Published in Investigative ophthalmology & visual science (17-09-2013)“…Neuroprotectin D1 (NPD1) is an anti-inflammatory and proresolving lipid mediator biosynthesized from the omega-3-polyunsaturated fatty acid docosahexaenoic…”
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Critical role of microRNA-155 in herpes simplex encephalitis
Published in The Journal of immunology (1950) (15-03-2014)“…HSV infection of adult humans occasionally results in life-threatening herpes simplex encephalitis (HSE) for reasons that remain to be defined. An animal…”
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Robo 4 Counteracts Angiogenesis in Herpetic Stromal Keratitis
Published in PloS one (31-12-2015)“…The cornea is a complex tissue that must preserve its transparency to maintain optimal vision. However, in some circumstances, damage to the eye can result in…”
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Galectin-1 reduces the severity of herpes simplex virus-induced ocular immunopathological lesions
Published in The Journal of immunology (1950) (01-05-2012)“…Stromal keratitis is a chronic immunopathological lesion of the eye caused by HSV-1 infection that can result in blindness. Because the inflammatory lesions…”
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Ocular neovascularization caused by herpes simplex virus type 1 infection results from breakdown of binding between vascular endothelial growth factor A and its soluble receptor
Published in The Journal of immunology (1950) (15-03-2011)“…The normal cornea is transparent, which is essential for normal vision, and although the angiogenic factor vascular endothelial growth factor A (VEGF-A) is…”
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An Anti-Inflammatory Role of VEGFR2/Src Kinase Inhibitor in Herpes Simplex Virus 1-Induced Immunopathology
Published in Journal of Virology (01-06-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Influence of galectin-9/Tim-3 interaction on herpes simplex virus-1 latency
Published in The Journal of immunology (1950) (01-12-2011)“…After HSV-1 infection, CD8(+) T cells accumulate in the trigeminal ganglion (TG) and participate in the maintenance of latency. However, the mechanisms…”
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TREX1 Knockdown Induces an Interferon Response to HIV that Delays Viral Infection in Humanized Mice
Published in Cell reports (Cambridge) (24-05-2016)“…Despite their antiviral effect, the in vivo effect of interferons on HIV transmission is difficult to predict, because interferons also activate and recruit…”
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Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes
Published in Cell (21-05-2015)Get full text
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19
TNFRSF25 Agonistic Antibody and Galectin-9 Combination Therapy Controls Herpes Simplex Virus-Induced Immunoinflammatory Lesions
Published in Journal of Virology (01-10-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Activation of endothelial roundabout receptor 4 reduces the severity of virus-induced keratitis
Published in The Journal of immunology (1950) (15-06-2011)“…Antiangiogenic molecules exert a feedback control to restrain pathological angiogenesis, which includes physical binding or inhibition of angiogenic signaling…”
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