Search Results - "Mulik, Rohit S."

Low-density lipoprotein-mediated delivery of docosahexaenoic acid selectively kills murine liver cancer cells by Reynolds, Lacy, Mulik, Rohit S, Wen, Xiaodong, Dilip, Archana, Corbin, Ian R

“…The natural omega-3 polyunsaturated fatty acid, docosahexaenoic acid (DHA), has recently been credited for possessing anticancer properties. Herein, we…”
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Low-density lipoprotein docosahexaenoic acid nanoparticles induce ferroptotic cell death in hepatocellular carcinoma by Ou, Weijun, Mulik, Rohit S., Anwar, Arnida, McDonald, Jeffrey G., He, Xiaoshun, Corbin, Ian R.

“…Low-density lipoprotein nanoparticles reconstituted with the natural omega-3 fatty acid, docosahexaenoic acid (LDL-DHA), have been reported to selectively kill…”
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Localized delivery of low-density lipoprotein docosahexaenoic acid nanoparticles to the rat brain using focused ultrasound by Mulik, Rohit S, Bing, Chenchen, Ladouceur-Wodzak, Michelle, Munaweera, Imalka, Chopra, Rajiv, Corbin, Ian R

“…Abstract Focused ultrasound exposures in the presence of microbubbles can achieve transient, non-invasive, and localized blood–brain barrier (BBB) opening,…”
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Transferrin mediated solid lipid nanoparticles containing curcumin: Enhanced in vitro anticancer activity by induction of apoptosis by Mulik, Rohit S., Mönkkönen, Jukka, Juvonen, Risto O., Mahadik, Kakasaheb R., Paradkar, Anant R.

“…Photodegradation and low bioavailability are major hurdles for the therapeutic use of curcumin. Aim of the present study was to formulate transferrin-mediated…”
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Corrigendum to “Transferrin mediated solid lipid nanoparticles containing curcumin: Enhanced in-vitro anticancer activity by induction of apoptosis”. [Int. J. Pharmac. 398 (2010) 190–203] by Mulik, Rohit S., Mönkkönen, Jukka, Juvonen, Risto O., Mahadik, Kakasaheb R., Paradkar, Anant R.

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Hepatic Arterial Infusion of Low-Density Lipoprotein Docosahexaenoic Acid Nanoparticles Selectively Disrupts Redox Balance in Hepatoma Cells and Reduces Growth of Orthotopic Liver Tumors in Rats by Wen, Xiaodong, Reynolds, Lacy, Mulik, Rohit S, Kim, Soo Young, Van Treuren, Tim, Nguyen, Liem H, Zhu, Hao, Corbin, Ian R

“…Background & Aims Dietary intake of the natural omega-3 fatty acid docosahexaenoic acid (DHA) has been implicated in protecting patients with viral hepatitis B…”
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Investigation into the distinct subcellular effects of docosahexaenoic acid loaded low-density lipoprotein nanoparticles in normal and malignant murine liver cells by Moss, Lacy R., Mulik, Rohit S., Van Treuren, Tim, Kim, Soo Young, Corbin, Ian R.

“…Recent studies have shown that low density lipoproteins reconstituted with the natural omega 3 fatty acid docosahexaenoic acid (LDL-DHA) is selectively…”
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ApoE3 Mediated Poly(butyl) Cyanoacrylate Nanoparticles Containing Curcumin: Study of Enhanced Activity of Curcumin against Beta Amyloid Induced Cytotoxicity Using In Vitro Cell Culture Model by Mulik, Rohit S, Mönkkönen, Jukka, Juvonen, Risto O, Mahadik, Kakasaheb R, Paradkar, Anant R

“…Beta amyloid plays a main role in the pathophysiology of Alzheimer’s disease by inducing oxidative stress in the brain. Curcumin, a natural antioxidant, is…”
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ApoE3 mediated polymeric nanoparticles containing curcumin: Apoptosis induced in vitro anticancer activity against neuroblastoma cells by Mulik, Rohit S., Mönkkönen, Jukka, Juvonen, Risto O., Mahadik, Kakasaheb. R., Paradkar, Anant R.

“…Curcumin, a natural phytoconstituent, is known to be therapeutically effective in the treatment of various cancers such as, breast cancer, lung cancer,…”
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Elucidating the structural organization of a novel low-density lipoprotein nanoparticle reconstituted with docosahexaenoic acid by Mulik, Rohit S., Zheng, Hui, Pichumani, Kumar, Ratnakar, James, Jiang, Qiu-Xing, Corbin, Ian R.

“…•LDL nanoparticles can incorporate >1100 docosahexaenoic acid (DHA) molecules per particle.•Spectroscopic NMR analyses indicate that reconstituted DHA…”
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Apoptosis-induced anticancer effect of transferrin-conjugated solid lipid nanoparticles of curcumin by Mulik, Rohit S., Mönkkönen, Jukka, Juvonen, Risto O., Mahadik, Kakasaheb R., Paradkar, Anant R.

“…Broad spectrum therapeutic potential of curcumin is usually hampered by its photodegradation and low bioavailability. Present investigation was designed with…”
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