Search Results - "Mulholland, Nicholas P."

Structure revision of cryptosporioptides and determination of the genetic basis for dimeric xanthone biosynthesis in fungi by Greco, Claudio, de Mattos-Shipley, Kate, Bailey, Andrew M, Mulholland, Nicholas P, Vincent, Jason L, Willis, Christine L, Cox, Russell J, Simpson, Thomas J

“…Three novel dimeric xanthones, cryptosporioptides A-C were isolated from Cryptosporiopsis sp. 8999 and their structures elucidated. Methylation of…”
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Uncovering biosynthetic relationships between antifungal nonadrides and octadrides by de Mattos-Shipley, Kate M. J, Spencer, Catherine E, Greco, Claudio, Heard, David M, O'Flynn, Daniel E, Dao, Trong T, Song, Zhongshu, Mulholland, Nicholas P, Vincent, Jason L, Simpson, Thomas J, Cox, Russell J, Bailey, Andrew M, Willis, Christine L

“…Maleidrides are a class of bioactive secondary metabolites unique to filamentous fungi, which contain one or more maleic anhydrides fused to a 7-, 8- or 9-…”
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Heterologous Production of Fungal Maleidrides Reveals the Cryptic Cyclization Involved in their Biosynthesis by Williams, Katherine, Szwalbe, Agnieszka J., Mulholland, Nicholas P., Vincent, Jason L., Bailey, Andrew M., Willis, Christine L., Simpson, Thomas J., Cox, Russell J.

“…Fungal maleidrides are an important family of bioactive secondary metabolites that consist of 7, 8, or 9‐membered carbocycles with one or two fused maleic…”
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The cycloaspeptides: uncovering a new model for methylated nonribosomal peptide biosynthesis by de Mattos-Shipley, Kate M J, Greco, Claudio, Heard, David M, Hough, Gemma, Mulholland, Nicholas P, Vincent, Jason L, Micklefield, Jason, Simpson, Thomas J, Willis, Christine L, Cox, Russell J, Bailey, Andrew M

“…The cycloaspeptides are bioactive pentapeptides produced by various filamentous fungi, which have garnered interest from the agricultural industry due to the…”
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Novel nonadride, heptadride and maleic acid metabolites from the byssochlamic acid producer Byssochlamys fulva IMI 40021 - an insight into the biosynthesis of maleidrides by Szwalbe, Agnieszka J, Williams, Katherine, O'Flynn, Daniel E, Bailey, Andrew M, Mulholland, Nicholas P, Vincent, Jason L, Willis, Christine L, Cox, Russell J, Simpson, Thomas J

“…The filamentous fungus Byssochlamys fulva strain IMI 40021 produces (+)-byssochlamic acid 1, its novel dihydroanalogue 2 and four related secondary…”
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A silicon-tethered tandem radical cyclisation–trapping strategy to the fully substituted cyclopentene ring in viridenomycin by Mulholland, Nicholas P., Pattenden, Gerald

“…Treatment of α-bromosilyl ether 27 derived from the substituted cyclopentenol 26 and (bromomethyl)chlorodimethylsilane, with…”
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A concise and straightforward total synthesis of (+/-)-salinosporamide A, based on a biosynthesis model by Mulholland, Nicholas P, Pattenden, Gerald, Walters, Iain A S

“…A 14-step total synthesis of (+/-)-salinosporamide A (1), a potent inhibitor of the 20S proteasome isolated from the marine bacterium Salinospora tropica, is…”
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A concise total synthesis of salinosporamide A by Mulholland, Nicholas P, Pattenden, Gerald, Walters, Iain A S

“…A concise and straightforward 14-step total synthesis of (+/-)-salinosporamide A, based on a diastereoselective acid-catalysed intramolecular cyclisation of to…”
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Heterologe Produktion pilzlicher Maleidride enthüllt die kryptische Cyclisierung in ihrer Biosynthese by Williams, Katherine, Szwalbe, Agnieszka J., Mulholland, Nicholas P., Vincent, Jason L., Bailey, Andrew M., Willis, Christine L., Simpson, Thomas J., Cox, Russell J.

“…Die von Pilzen produzierten Maleidride sind eine wichtige Klasse bioaktiver Sekundärmetaboliten, die aus sieben-, acht- oder neungliedrigen Carbocyclen…”
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Structure revision of cryptosporioptides and determination of the genetic basis for dimeric xanthone biosynthesis in fungi† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc05126g by Greco, Claudio, de Mattos-Shipley, Kate, Bailey, Andrew M., Mulholland, Nicholas P., Vincent, Jason L., Willis, Christine L., Cox, Russell J., Simpson, Thomas J.

“…Three novel dimeric xanthones, cryptosporioptides A–C were isolated from Cryptosporiopsis sp. 8999 and their structures elucidated. Three novel dimeric…”
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The cycloaspeptides: uncovering a new model for methylated nonribosomal peptide biosynthesisElectronic supplementary information (ESI) available. See DOI: 10.1039/c8sc00717a by de Mattos-Shipley, Kate M. J, Greco, Claudio, Heard, David M, Hough, Gemma, Mulholland, Nicholas P, Vincent, Jason L, Micklefield, Jason, Simpson, Thomas J, Willis, Christine L, Cox, Russell J, Bailey, Andrew M

“…The cycloaspeptides are bioactive pentapeptides produced by various filamentous fungi, which have garnered interest from the agricultural industry due to the…”
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The cycloaspeptides: uncovering a new model for methylated nonribosomal peptide biosynthesis† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc00717a by de Mattos-Shipley, Kate M. J., Greco, Claudio, Heard, David M., Hough, Gemma, Mulholland, Nicholas P., Vincent, Jason L., Micklefield, Jason, Simpson, Thomas J., Willis, Christine L., Cox, Russell J., Bailey, Andrew M.

“…The cycloaspeptide gene cluster includes a pathway-specific N -methyl transferase. Its disruption allowed incorporation of N -methylated amino acids provided…”
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Heterologe Produktion pilzlicher Maleidride enthüllt die kryptische Cyclisierung in ihrer Biosynthese by Williams, Katherine, Szwalbe, Agnieszka J., Mulholland, Nicholas P., Vincent, Jason L., Bailey, Andrew M., Willis, Christine L., Simpson, Thomas J., Cox, Russell J.

“…Die von Pilzen produzierten Maleidride sind eine wichtige Klasse bioaktiver Sekundärmetaboliten, die aus sieben‐, acht‐ oder neungliedrigen Carbocyclen…”
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A route to the fully substituted cyclopentane unit of viridenomycin using a tandem radical cyclisation–trapping strategy by Mulholland, Nicholas P., Pattenden, Gerald

“…[Display omitted] A silicon-tethered intramolecular radical cyclisation, in tandem with a radical trapping with allyltri- n-butylstannane forms the basis of a…”
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