Search Results - "Mulens, Vladimir"

The Use of Iron Oxide Nanoparticles to Reprogram Macrophage Responses and the Immunological Tumor Microenvironment by Mulens-Arias, Vladimir, Rojas, José Manuel, Barber, Domingo F.

“…The synthesis and functionalization of iron oxide nanoparticles (IONPs) is versatile, which has enhanced the interest in studying them as theranostic agents…”
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Dissecting the Inorganic Nanoparticle-Driven Interferences on Adhesome Dynamics by Mulens-Arias, Vladimir

“…Inorganic nanoparticles have emerged as an attractive theranostic tool applied to different pathologies such as cancer. However, the increment in inorganic…”
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Polyethylenimine-coated SPIONs trigger macrophage activation through TLR-4 signaling and ROS production and modulate podosome dynamics by Mulens-Arias, Vladimir, Rojas, José M, Pérez-Yagüe, Sonia, Morales, María P, Barber, Domingo F

“…Abstract Polyethylenimine (PEI) is widely used as transfection agent in preclinical studies, both in vitro and in vivo. Due to their unique chemical and…”
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Different coatings on magnetic nanoparticles dictate their degradation kinetics in vivo for 15 months after intravenous administration in mice by Portilla, Yadileiny, Fernández-Afonso, Yilian, Pérez-Yagüe, Sonia, Mulens-Arias, Vladimir, Morales, M Puerto, Gutiérrez, Lucía, Barber, Domingo F

“…The surface coating of iron oxide magnetic nanoparticle (MNPs) drives their intracellular trafficking and degradation in endolysosomes, as well as dictating…”
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Cationic Polyethyleneimine (PEI)–Gold Nanocomposites Modulate Macrophage Activation and Reprogram Mouse Breast Triple-Negative MET-1 Tumor Immunological Microenvironment by Mulens-Arias, Vladimir, Nicolás-Boluda, Alba, Carn, Florent, Gazeau, Florence

“…Nanomedicines based on inorganic nanoparticles have grown in the last decades due to the nanosystems’ versatility in the coating, tuneability, and physical and…”
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The Intrinsic Biological Identities of Iron Oxide Nanoparticles and Their Coatings: Unexplored Territory for Combinatorial Therapies by Mulens-Arias, Vladimir, Rojas, José Manuel, Barber, Domingo F

“…Over the last 20 years, iron oxide nanoparticles (IONPs) have been the subject of increasing investigation due to their potential use as theranostic agents…”
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Iron oxide and iron oxyhydroxide nanoparticles impair SARS-CoV-2 infection of cultured cells by DeDiego, Marta L, Portilla, Yadileiny, Daviu, Neus, López-García, Darío, Villamayor, Laura, Mulens-Arias, Vladimir, Ovejero, Jesús G, Gallo-Cordova, Ãlvaro, Veintemillas-Verdaguer, Sabino, Morales, M. Puerto, Barber, Domingo F

“…Coronaviruses usually cause mild respiratory disease in humans but as seen recently, some human coronaviruses can cause more severe diseases, such as the…”
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PI3K p110δ is expressed by gp38(-)CD31(+) and gp38(+)CD31(+) spleen stromal cells and regulates their CCL19, CCL21, and LTβR mRNA levels by Zotes, Teresa M, Spada, Roberto, Mulens, Vladimir, Pérez-Yagüe, Sonia, Sorzano, Carlos O, Okkenhaug, Klaus, Carrera, Ana C, Barber, Domingo F

“…The role of p110δ PI3K in lymphoid cells has been studied extensively, showing its importance in immune cell differentiation, activation and development…”
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An electrostatically conjugated-functional MNK1 aptamer reverts the intrinsic antitumor effect of polyethyleneimine-coated iron oxide nanoparticles in vivo in a human triple-negative cancer xenograft by Mulens-Arias, Vladimir, Portilla, Yadileiny, Pérez-Yagüe, Sonia, Ferreras-Martín, Raquel, Martín, M. Elena, González, Victor M., Barber, Domingo F.

“…Background Triple-negative breast cancer (TNBC) remains a difficult breast cancer subtype to treat as it exhibits a particularly aggressive behavior. The…”
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Immunogenicity and safety of a NeuGcGM3 based cancer vaccine: Results from a controlled study in metastatic breast cancer patients by Mulens, Vladimir, de la Torre, Ana, Marinello, Patricia, Rodríguez, Ronald, Cardoso, Jorge, Díaz, René, O´Farrill, Miguel, Macias, Amparo, Viada, Carmen, Saurez, Giselle, Carr, Adriana, Crombet, Tania, Mazorra, Zaima, Perez, Rolando, Fernández, Luis E.

“…Increased levels of NeuGc-containing gangliosides have been described in human breast cancer. A controlled Phase II clinical trial was conducted in patients…”
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PI3K p85 β regulatory subunit deficiency does not affect NK cell differentiation and increases NKG2D‐mediated activation by Rojas, José M., Spada, Roberto, Sanz‐Ortega, Laura, Morillas, Laura, Mejías, Raquel, Mulens‐Arias, Vladimir, Pérez‐Yagüe, Sonia, Barber, Domingo F.

“…Deficiency of the p85β regulatory subunit of PI3K does not affect NK cell differentiation and increases NK cell activity. Activation of NK cells depends on a…”
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NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery by Spada, Roberto, Rojas, Jose´ M., Pe´rez‐Yagu¨e, Sonia, Mulens, Vladimir, Cannata‐Ortiz, Pablo, Bragado, Rafael, Barber, Domingo F.

“…NKG2D ligand expression, NK cells, and cytokine expression by NK cells could play a role in the lupus nephritic process. NK cells are a major component of the…”
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Immunologic Response Elicited in Breast Cancer Patients Receiving a NeuGcGM3-based Vaccine as Adjuvant Therapy by Valdes-Zayas, Anet, Gonzalez, Zuyen, Mulens, Vladimir, Vega, Aliz M, Perez, Kirenia, Lorenzo-Luaces, Patricia, Rubio, Maria C, Estevez, Anabely, Curbelo, Idelmis, Fernandez, Luis E, Crombet, Tania, Mazorra, Zaima

“…This study aimed to investigate the immunogenicity of a cancer vaccine consisting of the NeuGcGM3 ganglioside combined with the outer membrane protein complex…”
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Rational Design of Fractal Gold Nanosphere Assemblies with Optimized Photothermal Conversion Using a Quantitative Structure Property Relationship (QSPR) Approach by Balfourier, Alice, Mulens-Arias, Vladimir, Gazeau, Florence, Carn, Florent

“…Assemblies of plasmonic nanoparticles have been proposed for various applications, including photothermal therapy, exploiting surface plasmon coupling…”
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Rational Design of Fractal Gold Nanosphere Assemblies with Optimized Photothermal Conversion Using a Quantitative Structure Property Relationship (QSPR) Approach by Balfourier, Alice, Mulens-Arias, Vladimir, Gazeau, Florence, Carn, Florent

“…Assemblies of plasmonic nanoparticles have been proposed for various applications, including photothermal therapy, exploiting surface plasmon coupling…”
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Comparación de la actividad de 2 factores estimuladores de colonias de granulocitos de producción nacional: Hebervital y Leukocim by Socarrás Ferrer, Bertha Beatriz, Macías Abraham, Consuelo, del Valle Pérez, Lázaro, Marsán Suárez, Vianed, Vergara Castellanos, Janet, Lam Díaz, Rosa María, González Iglesias, Ana Iris, Matamoros, María de los Angeles, Infante Cristiá, Ena, Guerra Segura, Osmel, Mulens Arias, Vladimir, Hernández Ramírez, Porfírio

“…En 35 pacientes que debían recibir terapia celular regenerativa se evaluó el efecto estimulante de 2 factores estimuladores de colonias de granulocitos de…”
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Endocytosis-driven gold nanoparticle fractal rearrangement in cells and its influence on photothermal conversion by Mulens-Arias, Vladimir, Balfourier, Alice, Nicolás-Boluda, Alba, Carn, Florent, Gazeau, Florence

“…Cellular endocytosis and intracellular trafficking of nanoparticles induce dynamic rearrangements that profoundly modify the physical properties of…”
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The surface coating of iron oxide nanoparticles drives their intracellular trafficking and degradation in endolysosomes differently depending on the cell type by Portilla, Yadileiny, Mulens-Arias, Vladimir, Paradela, Alberto, Ramos-Fernández, Antonio, Pérez-Yagüe, Sonia, Morales, M. Puerto, Barber, Domingo F.

“…Magnetic nanoparticles (MNPs) are potential theranostic tools that are biodegraded through different endocytic pathways. However, little is known about the…”
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Polyethyleneimine-assisted one-pot synthesis of quasi-fractal plasmonic gold nanocomposites as a photothermal theranostic agent by Mulens-Arias, Vladimir, Nicolás-Boluda, Alba, Gehanno, Alexandre, Balfourier, Alice, Carn, Florent, Gazeau, Florence

“…Gold nanoparticles have been thoroughly used in designing thermal ablative therapies and in photoacoustic imaging in cancer treatment owing to their unique and…”
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Theranostic Iron Oxide Nanoparticle Cargo Defines Extracellular Vesicle‐Dependent Modulation of Macrophage Activation and Migratory Behavior by Mulens‐Arias, Vladimir, Nicolás‐Boluda, Alba, Silva, Amanda K Andriola, Gazeau, Florence

“…Cells shed submicronic extracellular vesicles (EVs), containing a variety of soluble and membrane‐embedded factors, to mediate intercellular communication. EVs…”
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