Search Results - "Mulder, Jaap"
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Generation of infant- and pediatric-derived urinary induced pluripotent stem cells competent to form kidney organoids
Published in Pediatric research (01-03-2020)“…Background Human induced pluripotent stem cells (iPSCs) are a promising tool to investigate pathogenic mechanisms underlying human genetic conditions, such as…”
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Hedgehog-GLI signaling in Foxd1- positive stromal cells promotes murine nephrogenesis via TGFβ signaling
Published in Development (Cambridge) (01-07-2018)“…Normal kidney function depends on the proper development of the nephron: the functional unit of the kidney. Reciprocal signaling interactions between the…”
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Cephalosporin-Related Neurotoxicity in a Ceftriaxone-Treated Critically Ill Child: A Case Report
Published in Case reports in acute medicine (19-12-2023)“…Abstract Introduction: We describe a child with meningococcal sepsis who suffered cephalosporin-related neurotoxicity. Case Presentation: A four-year-old girl…”
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Range-wide patterns of human-mediated hybridisation in European wildcats
Published in Conservation genetics (01-04-2020)“…Hybridisation between wild taxa and their domestic congeners is a significant conservation issue. Domestic species frequently outnumber their wild relatives in…”
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Adult Height in Short Children Born SGA Treated with Growth Hormone and Gonadotropin Releasing Hormone Analog: Results of a Randomized, Dose-Response GH Trial
Published in The journal of clinical endocrinology and metabolism (01-11-2012)“…Context: GH treatment is effective in improving height in short children born small for gestational age (SGA). GH is thought to have limited effect when…”
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Vasculogenesis in kidney organoids upon transplantation
Published in npj Regenerative medicine (19-08-2022)“…Human induced pluripotent stem cell-derived kidney organoids have potential for disease modeling and to be developed into clinically transplantable auxiliary…”
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Increase in number of helminth species from Dutch red foxes over a 35-year period
Published in Parasites & vectors (03-04-2014)“…BACKGROUND: The red fox (Vulpes vulpes) is host to a community of zoonotic and other helminth species. Tracking their community structure and dynamics over…”
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Precision Health Resource of Control iPSC Lines for Versatile Multilineage Differentiation
Published in Stem cell reports (10-12-2019)“…Induced pluripotent stem cells (iPSC) derived from healthy individuals are important controls for disease-modeling studies. Here we apply precision health to…”
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Evidence for an increasing presence of Echinococcus multilocularis in foxes in The Netherlands
Published in International journal for parasitology (01-04-2008)“…Echinococcus multilocularis, a tapeworm causing alveolar echinococcosis which is considered a serious zoonosis known to affect humans, appears to be expanding…”
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Foreign Adopted Children Are a Source of Methicillin-Resistant Staphylococcus aureus Transmission to Countries With Low Prevalence
Published in The Pediatric infectious disease journal (01-06-2012)“…We report a 13.0% prevalence rate of methicillin-resistant Staphylococcus aureus (MRSA) carriers in foreign adopted children, who are frequently hospitalized…”
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Surveillance study of apparent life-threatening events (ALTE) in the Netherlands
Published in European journal of pediatrics (01-02-2010)“…SIDS and ALTE are different entities that somehow show some similarities. Both constitute heterogeneous conditions. The Netherlands is a low-incidence country…”
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Poldering a teaching qualification system in Higher Education in the Netherlands: a typical Dutch phenomenon
Published in Red U (01-12-2013)“…This article describes the process which led to the introduction of a University Teaching Qualification (UTQ) at research universities in the Netherlands…”
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First findings of Trichinella spiralis and DNA of Echinococcus multilocularis in wild raccoon dogs in the Netherlands
Published in International journal for parasitology. Parasites and wildlife (01-12-2016)“…The recent invasion of the raccoon dog in the Netherlands may be associated with the risk of introduction and spread of zoonotic pathogens. The aim of this…”
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Long-term effects of growth hormone (GH) treatment on body composition and bone mineral density in short children born small-for-gestational-age: six-year follow-up of a randomized controlled GH trial
Published in Clinical endocrinology (Oxford) (01-10-2007)“…Summary Context Alterations in the GH‐IGF‐I axis in short small‐for‐gestational‐age (SGA) children might be associated with abnormalities in bone mineral…”
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Randomized GH trial with two different dosages in combination with a GnRH analogue in short small for gestational age children: effects on metabolic profile and serum GH, IGF1, and IGFBP3 levels
Published in European journal of endocrinology (01-05-2010)“…BackgroundGnRH analogue (GnRHa) combined with GH treatment has been proposed to increase adult height. Effect on metabolic profile and GH, IGF1, and IGFBP3…”
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High Serum Levels of Growth Hormone (GH) and Insulin-Like Growth Factor-I (IGF-I) during High-Dose GH Treatment in Short Children Born Small for Gestational Age
Published in The journal of clinical endocrinology and metabolism (01-04-2006)“…Context: Epidemiological studies have indicated that high serum levels of GH and IGF-I are associated with long-term risks. Objective: The objective of the…”
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Constitutive Activation of Hedgehog Signaling Disrupts Nephrogenic and Stromal Differentiation: PO0873
Published in Journal of the American Society of Nephrology (01-10-2020)Get full text
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Hedgehog signalling in Foxd1+ embryonic kidney stromal progenitors controls nephron formation via Cxcl12 and Wnt5a
Published in The Journal of pathology (01-12-2023)“…Congenital anomalies of the kidney and urinary tract (CAKUT) are characterised by a spectrum of structural and histologic abnormalities and are the major cause…”
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Diagnosing a genetic disease in a donor-conceived child: case report and discussion of the ethical, legal, and practical issues
Published in Pediatric nephrology (Berlin, West) (17-10-2024)“…We describe the unexpected challenges pediatricians may experience when children conceived with assisted reproduction are diagnosed with a rare genetic…”
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226.2: Episomal DNA vector-induced EPO-overexpressing kidney organoids exhibit physiological effects after implantation
Published in Transplantation (01-09-2024)Get full text
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