Search Results - "Mulder, G."

Nestling telomere shortening, but not telomere length, reflects developmental stress and predicts survival in wild birds by Boonekamp, Jelle J., Mulder, G. A., Salomons, H. Martijn, Dijkstra, Cor, Verhulst, Simon

“…Developmental stressors often have long-term fitness consequences, but linking offspring traits to fitness prospects has remained a challenge. Telomere length…”
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Impact of resection margin status on recurrence and survival in pancreatic cancer surgery by Tummers, W. S., Groen, J. V., Sibinga Mulder, B. G., Farina‐Sarasqueta, A., Morreau, J., Putter, H., van de Velde, C. J., Vahrmeijer, A. L., Bonsing, B. A., Mieog, J. S., Swijnenburg, R. J.

“…Background The prognosis of patients with pancreatic ductal adenocarcinoma (PDAC) is poor and selection of patients for surgery is challenging. This study…”
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A zwitterionic near-infrared fluorophore for real-time ureter identification during laparoscopic abdominopelvic surgery by de Valk, Kim S., Handgraaf, Henricus J., Deken, Marion M., Sibinga Mulder, Babs G., Valentijn, Adrianus R., Terwisscha van Scheltinga, Anton G., Kuil, Joeri, van Esdonk, Michiel J., Vuijk, Jaap, Bevers, Rob F., Peeters, Koen C., Holman, Fabian A., Frangioni, John V., Burggraaf, Jacobus, Vahrmeijer, Alexander L.

“…Iatrogenic injury of the ureters is a feared complication of abdominal surgery. Zwitterionic near-infrared fluorophores are molecules with…”
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Image-Guided Surgery in Patients with Pancreatic Cancer: First Results of a Clinical Trial Using SGM-101, a Novel Carcinoembryonic Antigen-Targeting, Near-Infrared Fluorescent Agent by Hoogstins, Charlotte E. S., Boogerd, Leonora S. F., Sibinga Mulder, Babs G., Mieog, J. Sven D., Swijnenburg, Rutger Jan, van de Velde, Cornelis J. H., Farina Sarasqueta, Arantza, Bonsing, Bert A., Framery, Berenice, Pèlegrin, André, Gutowski, Marian, Cailler, Françoise, Burggraaf, Jacobus, Vahrmeijer, Alexander L.

“…Background Near-infrared (NIR) fluorescence is a promising novel imaging technique that can aid in intraoperative demarcation of pancreatic cancer (PDAC) and…”
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Cardiac output and peripheral vascular resistance during normotensive and hypertensive pregnancy – a systematic review and meta‐analysis by Mulder, EG, Haas, S, Mohseni, Z, Schartmann, N, Abo Hasson, F, Alsadah, F, Kuijk, SMJ, Drongelen, J, Spaanderman, MEA, Ghossein‐Doha, C

“…Background In‐depth insight into haemodynamic changes during normotensive pregnancy may help identify women at risk for gestational hypertensive complications…”
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Telomere shortening and survival in free-living corvids by Salomons, H. M., Mulder, G. A., van de Zande, L., Haussmann, M. F., Linskens, M. H. K., Verhulst, S.

“… Moreover, survival selection in adults was most conspicuous on relatively long telomeres. In conclusion, our longitudinal data indicate that the shortening…”
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Targeted next-generation sequencing has incremental value in the diagnostic work-up of patients with suspect pancreatic masses; a multi-center prospective cross sectional study by Achterberg, Friso B, Mulder, Babs G Sibinga, Janssen, Quisette P, Koerkamp, Bas Groot, Hol, Lieke, Quispel, Rutger, Bonsing, Bert A, Vahrmeijer, Alexander L, van Eijck, Casper H J, Roos, Daphne, Perk, Lars E, van der Harst, Erwin, Coene, Peter-Paul L O, Doukas, Michail, Smedts, Frank M M, Kliffen, Mike, van Velthuysen, Marie-Louise F, Terpstra, Valeska, Sarasqueta, Arantza Farina, Morreau, Hans, Mieog, J Sven D

“…The diagnostic process of patients with suspect pancreatic lesions is often lengthy and prone to repeated diagnostic procedures due to inconclusive results…”
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Selective tumor antigen vaccine delivery to human CD169+ antigen-presenting cells using ganglioside-liposomes by Affandi, Alsya J., Grabowska, Joanna, Olesek, Katarzyna, Venegas, Miguel Lopez, Barbaria, Arnaud, Rodríguez, Ernesto, Mulder, Patrick P. G., Pijffers, Helen J., Ambrosini, Martino, Kalay, Hakan, O’Toole, Tom, Zwart, Eline S., Kazemier, Geert, Nazmi, Kamran, Bikker, Floris J., Stöckl, Johannes, van den Eertwegh, Alfons J. M., de Gruijl, Tanja D., Storm, Gert, van Kooyk, Yvette, den Haan, Joke M. M.

“…Priming of CD8⁺ T cells by dendritic cells (DCs) is crucial for the generation of effective antitumor immune responses. Here, we describe a liposomal vaccine…”
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The rate of telomere loss is related to maximum lifespan in birds by Tricola, Gianna M., Simons, Mirre J. P., Atema, Els, Boughton, Raoul K., Brown, J. L., Dearborn, Donald C., Divoky, G., Eimes, John A., Huntington, Charles E., Kitaysky, Alexander S., Juola, Frans A., Lank, David B., Litwa, Hannah P., Mulder, Ellis G. A., Nisbet, Ian C. T., Okanoya, Kazuo, Safran, Rebecca J., Schoech, Stephan J., Schreiber, Elizabeth A., Thompson, Paul M., Verhulst, Simon, Wheelwright, Nathaniel T., Winkler, David W., Young, Rebecca, Vleck, Carol M., Haussmann, Mark F.

“…Telomeres are highly conserved regions of DNA that protect the ends of linear chromosomes. The loss of telomeres can signal an irreversible change to a cell's…”
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Persistent Systemic Inflammation in Patients With Severe Burn Injury Is Accompanied by Influx of Immature Neutrophils and Shifts in T Cell Subsets and Cytokine Profiles by Mulder, Patrick P G, Vlig, Marcel, Boekema, Bouke K H L, Stoop, Matthea M, Pijpe, Anouk, van Zuijlen, Paul P M, de Jong, Evelien, van Cranenbroek, Bram, Joosten, Irma, Koenen, Hans J P M, Ulrich, Magda M W

“…Severe burn injury causes local and systemic immune responses that can persist up to months, and can lead to systemic inflammatory response syndrome, organ…”
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Intraoperative Molecular Fluorescence Imaging of Pancreatic Cancer by Targeting Vascular Endothelial Growth Factor: A Multicenter Feasibility Dose-Escalation Study by Mulder, Babs G Sibinga, Koller, Marjory, Duiker, Evelien W, Sarasqueta, Arantza Farina, Burggraaf, Jakobus, Meijer, Vincent E de, Vahrmeijer, Alexander L, Hoogwater, Frederik J H, Bonsing, Bert A, van Dam, Gooitzen M, Mieog, J Sven D, Pranger, Bobby K

“…Tumor visualization with near-infrared fluorescence (NIRF) imaging might aid exploration and resection of pancreatic cancer by visualizing the tumor in real…”
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Association between blood lactate levels, Sequential Organ Failure Assessment subscores, and 28-day mortality during early and late intensive care unit stay: A retrospective observational study by Jansen, Tim C, van Bommel, Jasper, Woodward, Roger, Mulder, Paul G. H, Bakker, Jan

“…OBJECTIVES:To evaluate whether the level and duration of increased blood lactate levels are associated with daily Sequential Organ Failure Assessment (SOFA)…”
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The COSMAM TRIAL a prospective cohort study of quality of life and cosmetic outcome in patients undergoing breast conserving surgery by Catsman, Coriene J L M, Beek, Martinus A, Voogd, Adri C, Mulder, Paul G H, Luiten, Ernest J T

“…Cosmetic result in breast cancer surgery is gaining increased interest. Currently, some 30-40% of the patients treated with breast conserving surgery (BCS) are…”
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Azithromycin maintenance treatment in patients with frequent exacerbations of chronic obstructive pulmonary disease (COLUMBUS): a randomised, double-blind, placebo-controlled trial by Uzun, Sevim, MD, Djamin, Remco S, MD, Kluytmans, Jan A J W, Prof, Mulder, Paul G H, PhD, van't Veer, Nils E, MSc, Ermens, Anton A M, PhD, Pelle, Aline J, PhD, Hoogsteden, Henk C, Prof, Aerts, Joachim G J V, MD, van der Eerden, Menno M, Dr

“…Summary Background Macrolide resistance is an increasing problem; there is therefore debate about when to implement maintenance treatment with macrolides in…”
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Therapeutic potential of vasopressin V2 receptor antagonist in a mouse model for autosomal dominant polycystic kidney disease: optimal timing and dosing of the drug by Meijer, E., Gansevoort, R. T., de Jong, P. E., van der Wal, A. M., Leonhard, W. N., de Krey, S. R., van den Born, J., Mulder, G. M., van Goor, H., Struck, J., de Heer, E., Peters, D. J. M.

“…Background. The renoprotective effect of vasopressin V2 receptor antagonist (V2RA) is currently being tested in a clinical trial in early autosomal dominant…”
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Risk of multiple pancreatic cancers in CDKN2A-p16-Leiden mutation carriers by Ibrahim, Isaura, Sibinga Mulder, Babs G, Bonsing, Bert, Morreau, Hans, Farina Sarasqueta, Arantza, Inderson, Akin, Luelmo, Saskia, Feshtali, Shirin, Potjer, Thomas P, de Vos Tot Nederveen Cappel, Wouter, Wasser, Martin, Vasen, Hans F A

“…CDKN2A-p16-Leiden mutation carriers have a substantial risk of developing pancreatic ductal adenocarcinoma (PDAC). One of the main clinical features of…”
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Real-time surgical margin assessment using ICG-fluorescence during laparoscopic and robot-assisted resections of colorectal liver metastases by Achterberg, Friso B, Sibinga Mulder, Babs G, Meijer, Ruben P J, Bonsing, Bert A, Hartgrink, Henk H, Mieog, J Sven D, Zlitni, Aimen, Park, Seung-Min, Farina Sarasqueta, Arantza, Vahrmeijer, Alexander L, Swijnenburg, Rutger-Jan

“…Almost a third of the resections in patients with colorectal liver metastases (CRLM) undergoing curative surgery, end up being tumor-margin positive (≤1 mm…”
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Long-term follow-up after near-infrared fluorescence-guided resection of colorectal liver metastases: A retrospective multicenter analysis by Handgraaf, H.J.M, Boogerd, L.S.F, Höppener, D.J, Peloso, A, Sibinga Mulder, B.G, Hoogstins, C.E.S, Hartgrink, H.H, van de Velde, C.J.H, Mieog, J.S.D, Swijnenburg, R.J, Putter, H, Maestri, M, Braat, A.E, Frangioni, J.V, Vahrmeijer, A.L

“…Abstract Background Several studies demonstrated that intraoperative near-infrared fluorescence (NIRF) imaging using indocyanine green (ICG) identifies…”
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Quantification of near-infrared fluorescence imaging with indocyanine green in free flap breast reconstruction by Van Den Hoven, P., Verduijn, P.S., Van Capelle, L., Tange, F.P., Michi, M., Corion, L.U.M., Sibinga Mulder, B.G., Mureau, M.A.M., Vahrmeijer, A.L., Van Der Vorst, J.R.

“…One of the complications of free flap breast reconstruction is the occurrence of skin and fat necrosis. Intra-operative use of near-infrared (NIR) fluorescence…”
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Staging laparoscopy with ultrasound and near-infrared fluorescence imaging to detect occult metastases of pancreatic and periampullary cancer by Handgraaf, H J M, Sibinga Mulder, B G, Shahbazi Feshtali, S, Boogerd, L S F, van der Valk, M J M, Fariña Sarasqueta, A, Swijnenburg, R J, Bonsing, B A, Vahrmeijer, A L, Mieog, J S D

“…Up to 38% of pancreatic and periampullary cancer patients undergoing curative intended surgery turn out to have incurable disease. Therefore, staging…”
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