Search Results - "Mulder, G J"

The incorporation of different demand concepts in the job demand-control model: effects on health care professionals by de Jonge, Jan, Mulder, Marike J.G.P, Nijhuis, Frans J.N

“…This paper reports a study of 212 health care professionals that focuses on job characteristics as predictors of employee health. By means of covariance…”
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Isolated hepatic perfusion for the treatment of colorectal metastases confined to the liver: recent trends and perspectives by Rothbarth, J, Tollenaar, R.A.E.M, Schellens, J.H.M, Nortier, J.W.R, Kool, L.J.Schultze, Kuppen, P.J.K, Mulder, G.J, van de Velde, C.J.H

“…Isolated hepatic perfusion (IHP) involves a method of complete vascular isolation of the liver to allow treatment of liver tumours with toxic systemic doses…”
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Increased local cytostatic drug exposure by isolated hepatic perfusion: a phase I clinical and pharmacologic evaluation of treatment with high dose melphalan in patients with colorectal cancer confined to the liver by VAHRMEIJER, A. L, VAN DIERENDONCK, J. H, VAN DE VELDE, C. J. H, KEIZER, H. J, BEIJNEN, J. H, TOLLENAAR, R. A. E. M, PIJL, M. E. J, MARINELLI, A, KUPPEN, P. J. K, VAN BOCKEL, J. H, MULDER, G. J

“…A phase I dose-escalation study was performed to determine whether isolated hepatic perfusion (IHP) with melphalan (L-PAM) allows exposure of the liver to much…”
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Glucuronidation and its role in regulation of biological activity of drugs by Mulder, G J

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Comparison of Amplicor, in-house PCR, and conventional culture for detection of Mycobacterium tuberculosis in clinical samples by SCHIRM, J, OOSTENDORP, L. A. B, MULDER, J. G

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cytotoxicity and Biotransformation of the Anticancer Drug Perillyl Alcohol in PC12 Cells and in the Rat by Boon, Piet J.M., van der Boon, Dennis, Mulder, Gerard J.

“…The cytotoxic monoterpene perillyl alcohol (POH) has anticancer properties. We investigated its cytotoxicity in PC12 cells in relation to its…”
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Role of mitochondrial Ca2+ in the oxidative stress-induced dissipation of the mitochondrial membrane potential. Studies in isolated proximal tubular cells using the nephrotoxin 1,2-dichlorovinyl-L-cysteine by VAN DE WATER, B, ZOETEWEIJ, J. P, DE BONT, H. J. G. M, MULDER, G. J, NAGELKERKE, J. F

“…The relationship between mitochondrial Ca2+, oxidative stress, and a dissipation of the mitochondrial membrane potential (delta psi) was investigated in…”
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Antibiotic susceptibility profiles of Prevotella species in The Netherlands by Veloo, A.C.M, Boiten, K.E, Wekema-Mulder, G.J, Rurenga, P, Singadji, Z.M, Scoop, G.G.G, van Winkelhoff, A.J

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Metabolic activation pathway for the formation of DNA adducts of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rat extrahepatic tissues by Kaderlik, K R, Minchin, R F, Mulder, G J, Ilett, K F, Daugaard-Jenson, M, Teitel, C H, Kadlubar, F F

“…The food-borne mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induces tumors in colon of male rats and has been implicated in the etiology of…”
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Slime-producing properties of coagulase-negative staphylococci isolated from blood cultures by Mulder, J.G., Degener, J.E.

“…To evaluate five methods for the determination of slime-producing properties in coagulase-negative staphylococci (CNS). One hundred and sixty-two strains of…”
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p53 protein expression by hepatocarcinogens in the rat liver and its potential role in mitoinhibition of normal hepatocytes as a mechanism of hepatic tumour promotion by VAN GIJSSEL, H. E, MAASSEN, C. B. M, MULDER, G. J, MEERMAN, J. H. N

“…The tumour suppressor gene p53 is expressed in response to DNA-damage; its protein product blocks cells in the G1-phase of the cell cycle. This gives cells…”
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Glucuronidation of N-hydroxy heterocyclic amines by human and rat liver microsomes by Kaderlik, K R, Mulder, G J, Turesky, R J, Lang, N P, Teitel, C H, Chiarelli, M P, Kadlubar, F F

“…The food-borne carcinogenic and mutagenic heterocyclic aromatic amines undergo bioactivation to the corresponding N-hydroxy (OH)-arylamines and the subsequent…”
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Glutathione Conjugation of 4-Hydroxy-trans-2,3-nonenal in the Rat in Vivo, the Isolated Perfused Liver and Erythrocytes by Boon, Piet J.M., Marinho, H.Susana, Oosting, Roelof, Mulder, Gerard J.

“…The formation of glutathione (GSH) conjugates of racemic 4-hydroxy-trans-2,3-nonenal (4-HNE) in the rat in vivo in the perfused rat liver and rat erythrocytes…”
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The role of various Bcl-2 domains in the anti-proliferative effect and modulation of cellular glutathione levels: a prominent role for the BH4 domain by Hoetelmans, R. W. M., Vahrmeijer, A. L., Van Vlierberghe, R. L. P., Keijzer, R., Van De Velde, C. J. H., Mulder, G. J., Van Dierendonck, J. H.

“… Reduced cell proliferation and increased levels of cellular glutathione (GSH) are characteristic for cells that overexpress the anti‐apoptotic Bcl‐2 protein…”
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An experimental minimally invasive perfusion technique for the treatment of liver metastases by Rothbarth, J, Pijl, M.E.J, Tollenaar, R.A.E.M, Tijl, F, Ivancev, G, Mulder, G.J, Kuppen, P.J.K, van de Velde, C.J.H, Schultze Kool, L.J

“…Aim: Isolated hepatic perfusion (IHP) is an invasive, technically difficult, non-repeatable and demanding operation. In this study we report the development of…”
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Comparison of disk diffusion, the E Test, and detection of mecA for determination of methicillin resistance in coagulase-negative staphylococci by MULDER, J. G

“…The aim of this study was to find a reliable, fast, and simple alternative to the methicillin disk method for determination of methicillin resistance in…”
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Lack of p53 protein expression in preneoplastic rat hepatocytes in vitro after exposure to N-acetoxy-acetylaminofluorene, X-rays or a proteasome inhibitor by van Gijssel, H.E, Stenius, U, Mulder, G.J, Meerman, J.H.N

“…Clonal expansion of initiated cells is an important process in carcinogenesis. Loss of functional p53 protein in initiated, preneoplastic cells might be…”
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Effect of glutathione depletion on inhibition of cell cycle progression and induction of apoptosis by melphalan (L-phenylalanine mustard) in human colorectal cancer cells by Vahrmeijer, Alexander L, van Dierendonck, Jan Hein, Schutrups, Jan, van de Velde, Cornelis J.H, Mulder, Gerard J

“…Intracellular levels of glutathione have been shown to affect the sensitivity of cells to cell death-inducing stimuli, as well as the mode of cell death. We…”
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The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence by Burchell, B, Nebert, D W, Nelson, D R, Bock, K W, Iyanagi, T, Jansen, P L, Lancet, D, Mulder, G J, Chowdhury, J R, Siest, G

“…A nomenclature system for the UDP glucuronosyltransferase superfamily is proposed, based on divergent evolution of the genes. A total of 26 distinct cDNAs in…”
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Prevention of cycloheximide-induced apoptosis in hepatocytes by adenosine and by caspase inhibitors by Blom, W.Marty, de Bont, Hans J.G.M, Meijerman, Irma, Mulder, Gerard J, Nagelkerke, J.Fred

“…The mechanism by which cycloheximide induces apoptosis in isolated rat hepatocytes was studied. Cycloheximide (1–300 μM) induced apoptosis within 3–4 hr in the…”
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