Search Results - "Mulder, Anke M"
-
1
Transmission electron microscopy as an orthogonal method to characterize protein aggregates
Published in Journal of pharmaceutical sciences (01-02-2015)“…Aggregation of protein-based therapeutics is a challenging problem in the biopharmaceutical industry. Of particular concern are implications for product…”
Get more information
Journal Article -
2
Toolbox for non-intrusive structural and functional analysis of recombinant VLP based vaccines: a case study with hepatitis B vaccine
Published in PloS one (06-04-2012)“…Fundamental to vaccine development, manufacturing consistency, and product stability is an understanding of the vaccine structure-activity relationship. With…”
Get full text
Journal Article -
3
Endocannabinoid Metabolism in the Absence of Fatty Acid Amide Hydrolase (FAAH): Discovery of Phosphorylcholine Derivatives of N-Acyl Ethanolamines
Published in Biochemistry (Easton) (26-09-2006)“…Lipid transmitters are tightly regulated by a balance of biosynthetic and degradative enzymes. Termination of the activity of the N-acyl ethanolamine (NAE)…”
Get full text
Journal Article -
4
A New Model for Binding of Kinesin 13 to Curved Microtubule Protofilaments
Published in The Journal of cell biology (06-04-2009)“…Kinesin motor proteins use adenosine triphosphate hydrolysis to do work on microtubules (MTs). Most kinesins walk along the MT, but class 13 kinesins instead…”
Get full text
Journal Article -
5
Visualizing Ribosome Biogenesis: Parallel Assembly Pathways for the 30S Subunit
Published in Science (American Association for the Advancement of Science) (29-10-2010)“…Ribosomes are self-assembling macromolecular machines that translate DNA into proteins, and an understanding of ribosome biogenesis is central to cellular…”
Get full text
Journal Article -
6
Automation in single-particle electron microscopy connecting the pieces
Published in Methods in enzymology (2010)“…Throughout the history of single-particle electron microscopy (EM), automated technologies have seen varying degrees of emphasis and development, usually…”
Get more information
Journal Article -
7
Visualizing Ribosome Biogenesis: Parallel Assembly Pathways for 30S Subunit
Published in Biophysical journal (01-02-2011)Get full text
Journal Article -
8
Cryo Transmission Electron Microscopy as an Orthogonal Tool for Characterization of Biopharmaceuticals
Published in Journal of biomolecular techniques (01-01-2012)Get full text
Journal Article -
9
Visualizing Ribosome Biogenesis: Parallel Assembly Pathways for the 30 S Subunit
Published in Science (American Association for the Advancement of Science) (29-10-2010)“…Ribosome Assembly Pathway The bacterial ribosome is made up of two subunits (50 S and 30 S ) that together comprise 55 proteins and three large ribosomal RNAs…”
Get full text
Journal Article -
10
Visualizing biological complexity: Toward discovery based single particle electron microscopy
Published 01-01-2010“…The advent of an information age in which cutting edge technologies and important scientific discoveries are accessible to a global audience at an instant's…”
Get full text
Dissertation