Search Results - "Mukkanti, Khagga"
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A New Ecological RP-HPLC Method for the Determination of Pitavastatin, Fenofibrate and Their Impurities in a Novel Fixed Dose Combination
Published in Chromatographia (01-02-2022)“…We developed a simple, rapid, ecological RP-HPLC method for the estimation of Pitavastatin (PIT), Fenofibrate (FEN), and their impurities in a novel fixed dose…”
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2
Novel Stability-Indicating UHPLC Method Development and Validation for the Quantification of Perindopril, Amlodipine and Their Impurities in Pharmaceutical Formulations: Application of QbD Approach
Published in Chromatographia (01-10-2020)“…We developed a novel, rapid, sensitive, and stability-indicating UHPLC method for quantification of Perindopril (PER), Amlodipine (AML), and their impurities…”
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3
Assembly of Benzothiazine and Triazole in a Single Molecular Entity: Synthesis of -Oxicam Derived Novel Molecules as Potential Antibacterial/ Anti-cancer Agents
Published in Mini reviews in medicinal chemistry (01-01-2020)“…Benzothiazine derivatives, because of their various biological activities have attracted particular attention in Med Chem and drug discovery efforts. The…”
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4
Synthesis, anticonvulsant, sedative and anxiolytic activities of novel annulated pyrrolo[1,4]benzodiazepines
Published in International journal of molecular sciences (18-09-2014)“…Four new pentacyclic benzodiazepine derivatives (PBDTs 13-16) were synthesized by conventional thermal heating and microwave-assisted intramolecular…”
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5
A simple approach to highly functionalized benzo[ b]furans from phenols and aryl iodides via aryl propargyl ethers
Published in Tetrahedron letters (30-06-2008)“…A variety of mono- and disubstituted phenols are alkylated with propargyl bromide to give phenyl 2-propynyl ethers, which were further coupled with aryl…”
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6
Transdermal therapeutic system of isradipine: Effect of hydrophilic and hydrophobic matrix on In Vitro and Ex vivo characteristics
Published in Archives of pharmacal research (01-07-2010)“…Isradipine (ISDP) is an effective calcium channel blocker used in the treatment of hypertension. It undergoes extensive first pass metabolism and…”
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7
Application of [3 + 2]-Cycloaddition in the Synthesis of Valdecoxib
Published in Synthetic communications (01-03-2012)“…A large scale synthesis of valdecoxib 1 is described. Our work features potential application of [3 + 2]-dipolar cycloaddition involving enamine and in…”
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Development and validation of a Sensitive bioanalytical method for the quantitative estimation of Pantoprazole in human plasma samples by LC–MS/MS: Application to bioequivalence study
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-06-2010)“…The present study aims at developing a simple, sensitive and specific liquid chromatography–tandem mass spectrometry (LC–MS/MS) method for the quantification…”
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9
Synthesis and cytotoxicity testing of new amido-substituted triazolopyrrolo[2,1-c][1,4]benzodiazepine (PBDT) derivatives
Published in Molecules (Basel, Switzerland) (25-07-2012)“…A series of amido-substituted triazolopyrrolo[2,1-c][1,4]benzodiazepine (PBDT) derivatives was synthesized from isatoic anhydride, and their cytotoxicity…”
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10
N-{2-[3-(3-Formyl-2-oxoquinolin-1(2H)-yl)prop-1-ynyl]phenyl}acetamide
Published in MolBank (01-09-2013)“…The title compound, N-{2-[3-(3-formyl-2-oxoquinolin-1(2H)-yl)prop-1-ynyl]phenyl}acetamide was synthesized in high yield by Sonogashira cross coupling of…”
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11
2-(6-Methoxynaphthalen-2-yl)propionic acid (1,3-dimethylbutylidene)hydrazide
Published in MolBank (01-12-2011)“…The title compound, 2-(6-methoxynaphthalen-2-yl)propionic acid (1,3-dimethylbutylidene)hydrazide was synthesized in high yield by the reaction of…”
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12
N-(2-Phenoxy-4-(3-phenoxyprop-1-ynyl)phenyl)methane Sulfonamide
Published in MolBank (01-03-2012)“…The title compound, N-(2-phenoxy-4-(3-phenoxyprop-1-ynyl)phenyl) methanesulfonamide was synthesized in high yield by Sonogashira cross coupling of…”
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13
Nimesulide Based Novel Glycolamide Esters: Their Design, Synthesis, and Pharmacological Evaluation
Published in Journal of chemistry (01-01-2013)“…The nimesulide based novel glycolamide esters were designed and synthesized for the first time via a three-step method starting from nimesulide. Structures of…”
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14
N-(4-Methylsulfonamido-3-phenoxyphenyl)-9,10-dihydro-9,10-ethanoanthracene-11,12-dicarboximide
Published in MolBank (01-12-2011)“…The title compound, N-(4-methylsulfonamido-3-phenoxyphenyl)-9,10-dihydro-9,10-ethanoanthracene-11,12-dicarboximide was synthesized in high yield by reaction of…”
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15
Synthesis, biological evaluation, and docking study of a series of 1,4‐disubstituted 1,2,3‐triazole derivatives with an indole‐triazole‐peptide conjugate
Published in Journal of heterocyclic chemistry (01-08-2020)“…A series of new compounds containing an indole‐triazole‐peptide conjugate were designed as potential agents possessing the dual anti‐bacterial and anticancer…”
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16
1H-1,2,3-Triazolyl-substituted 1,3,4-oxadiazole derivatives containing structural features of ibuprofen/naproxen: Their synthesis and antibacterial evaluation
Published in Bioorganic & medicinal chemistry letters (01-11-2016)“…[Display omitted] 1H-1,2,3-Triazolyl-substituted 1,3,4-oxadiazole derivatives containing structural features of ibuprofen/naproxen were synthesized for the…”
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Identification, isolation, and synthesis of seven novel impurities of anti‐diabetic drug Repaglinide
Published in Drug testing and analysis (01-01-2018)“…Seven unknown impurities in Repaglinide bulk drug batches at below 0.1% (ranging from 0.05 to 0.10%) were detected by an ultra‐performance liquid…”
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18
Synthesis and anti-neuroinflammatory activity studies of substituted 3,4-dihydroquinoxalin-2-amine derivatives
Published in Tetrahedron letters (30-05-2012)“…Structures of 4l and 4n compounds having biological activity. We demonstrate the synthesis of multifunctional 3,4-dihydroquinoxalin-2-amine derivatives 4…”
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19
Synthesis, Biological Evaluation and In silico Studies of Compounds Based on Tryptophan‐Naproxen‐Triazole Hybrids
Published in ChemistrySelect (Weinheim) (11-12-2020)“…A hybrid of three different frameworks e. g. tryptophan, naproxen and triazole has been explored for the identification of potential antibacterial / anticancer…”
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Synthesis, Chemotherapeutic Screening and Docking Studies of NSAID Inserted Peptide‐Triazole Hybrid Molecules
Published in ChemistrySelect (Weinheim) (16-06-2020)“…A series of peptide based new tryptophan‐1,2,3‐triazole‐naproxen derivatives were explored as prospective antibacterial / cytotoxic agents. These derivatives…”
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