Search Results - "Mukaddam‐Daher, S"

Moxonidine improves cardiac structure and performance in SHR through inhibition of cytokines, p38 MAPK and Akt by Aceros, H, Farah, G, Cobos‐Puc, L, Stabile, AM, Noiseux, N, Mukaddam‐Daher, S

“…BACKGROUND AND PURPOSE Regression of left ventricular hypertrophy by moxonidine, a centrally acting sympatholytic imidazoline compound, results from a…”
Get full text

Oxytocin is a cardiovascular hormone by Gutkowska, J, Jankowski, M, Mukaddam-Daher, S, McCann, S M

“…Oxytocin (OT), a nonapeptide, was the first hormone to have its biological activities established and chemical structure determined. It was believed that OT is…”
Get full text

Pregnancy alters nitric oxide synthase and natriuretic peptide systems in the rat left ventricle by Jankowski, M, Wang, D, Mukaddam-Daher, S, Gutkowska, J

“…Cyclic guanosine monophosphate (cGMP), which is implicated in cardiac cell growth and function, is synthesized by cytoplasmic soluble guanylyl cyclase (GC)…”
Get full text

Control of left ventricular mass by moxonidine involves reduced DNA synthesis and enhanced DNA fragmentation by Paquette, P‐A, Duguay, D, Ayoubi, R El‐, Menaouar, A, Danalache, B, Gutkowska, J, DeBlois, D, Mukaddam‐Daher, S

“…Background and purpose: Left ventricular hypertrophy (LVH) is a maladaptive process associated with increased cardiovascular risk. Regression of LVH is…”
Get full text

Imidazoline receptors in the heart: a novel target and a novel mechanism of action that involves atrial natriuretic peptides by Mukaddam-Daher, S, Gutkowska, J

“…Chronic stimulation of sympathetic nervous activity contributes to the development and maintenance of hypertension, leading to left ventricular hypertrophy…”
Get full text

Cardiac Effects of Moxonidine in Spontaneously Hypertensive Obese Rats by MUKADDAM-DAHER, S, MENAOUAR, A, EL-AYOUBI, R, GUTKOWSKA, J, JANKOWSKI, M, VELLIQUETTE, RA, ERNSBERGER, P

“…: Moxonidine, an imidazoline receptor agonist that acts centrally to inhibit sympathetic activity, has been shown to reduce effectively blood pressure, fasting…”
Get full text

Regulation of cardiac oxytocin system and natriuretic peptide during rat gestation and postpartum by Mukaddam-Daher, S, Jankowski, M, Wang, D, Menaouar, A, Gutkowska, J

“…We have recently uncovered the presence of an oxytocin system in the heart and found that oxytocin is a physiological regulator of atrial natriuretic peptide…”
Get full text

Normalization of Up-Regulated Cardiac Imidazoline I1-Receptors and Natriuretic Peptides by Chronic Treatment with Moxonidine in Spontaneously Hypertensive Rats by EL-AYOUBI, R, MENAOUAR, A, GUTKOWSKA, J, MUKADDAM-DAHER, S

“…: The effect of treatment with moxonidine (120 mg/kg/h sc, 4 weeks) on cardiac I1‐receptors and natriuretic peptide synthesis was evaluated in spontaneously…”
Get full text

083 In Vitro Nischarin Over-Expression Opposes Cell-Death Induced by Oxidative Stress by Aceros, H, Noiseux, N, Mukaddam-Daher, S

Get full text

Corticotropin-Releasing Hormone Causes Antidiuresis and Antinatriuresis by Stimulating Vasopressin and Inhibiting Atrial Natriuretic Peptide Release in Male Rats by Gutkowska, J., Jankowski, M., Mukaddam-Daher, S., McCann, S. M.

“…In both normally hydrated and volume-expanded rats, there was a biphasic effect of corticotropin-releasing hormone (CRH) (1-10 μ g, i.v.) on renal function…”
Get full text

032 TNF-α and moxonidine interact at the level of MAPKs and Akt in cardiac cells by Aceros, H, Cobos-Puc, L, Farah, G, Abass, M, Noiseux, N, Mukaddam-Daher, S

Get full text

Regulation of the natriuretic peptide system in rat uterus during the estrous cycle by Reis, A M, Jankowski, M, Mukaddam-Daher, S, Tremblay, J, Dam, T V, Gutkowska, J

“…Uterine natriuretic peptides may be involved in the alterations that occur in the uterus during the estrous cycle through its role in hydromineral balance. The…”
Get more information

Regulation of renal atrial natriuretic peptide receptors in pregnant sheep by Mukaddam-Daher, S, Gutkowska, J, Tremblay, J, Dam, T V, Quillen, Jr, E W

“…These studies were designed to characterize the atrial natriuretic peptide (ANF) receptor subtypes (guanylyl cyclase GC-A and GC-B and ANF-C) in normal sheep…”
Get more information

Normalization of Up‐Regulated Cardiac Imidazoline I 1 ‐Receptors and Natriuretic Peptides by Chronic Treatment with Moxonidine in Spontaneously Hypertensive Rats by EL‐AYOUBI, R, MENAOUAR, A, GUTKOWSKA, J, MUKADDAM‐DAHER, S

“…A bstract : The effect of treatment with moxonidine (120 mg/kg/h sc, 4 weeks) on cardiac I 1 ‐receptors and natriuretic peptide synthesis was evaluated in…”
Get full text

Enhanced natriuretic response to intrarenal infusion of atrial natriuretic factor during ovine pregnancy by Fan, L, Mukaddam-Daher, S, Gutkowska, J, Nuwayhid, B S, Quillen, Jr, E W

“…Volume-loading and intravenous infusion studies have suggested that the natriuretic response of atrial natriuretic factor (ANF) is blunted or unaltered during…”
Get full text

The Cardiovascular and Renal Effects of the Potent and Highly Selective μ Opioid Agonist [Dmt1]DALDA by Gutkowska, J, Mukaddam-Daher, S, Jankowski, M, Schiller, P W

“…The cardiovascular and renal effects of a μ opioid agonist, [Dmt]DALDA, were studied in conscious Sprague-Dawley rats. During the first hour postinjection,…”
Get full text

C-type natriuretic peptide and the guanylyl cyclase receptors in the rat ovary are modulated by the estrous cycle by JANKOWSKI, M, REIS, A. M, MUKADDAM-DAHER, S, DAM, T.-V, FAROOKHI, R, GUTKOWSKA, J

“…We have previously shown that rat ovaries synthesize atrial natriuretic peptide (ANP) and express the cognate guanylyl cyclase (GC-A and GC-B) receptors for…”
Get full text

Indirect hypertensive actions of long-term intracarotid angiotensin II infusion during ovine pregnancy by Mukaddam-Daher, S C, Aberdeen, G W, Cha, S C, Gutkowska, J, Nuwayhid, B S, Quillen, Jr, E W

“…Angiotensin II (AngII) influences the regulation of mean arterial pressure (MAP) through numerous mechanisms, including an action of circulating AngII on the…”
Get more information

N002: The renal effects of corticotropin releasing hormone: Implication of vasopressin and atrial natriuretic peptide by Gutkowska, J., Jankowski, M., Mukaddam-Daher, S., McCann, S.M.

“…To evaluate the hypothesized renal actions of corticotropin releasing hormone (CRH), adult male conscious normally hydrated or volume-expanded rats (6 ml…”
Get full text

Characterization and distribution of natriuretic peptide receptors in the rat uterus by Dos Reis, A M, Fujio, N, Dam, T V, Mukaddam-Daher, S, Jankowski, M, Tremblay, J, Gutkowska, J

“…Atrial natriuretic peptide (ANP) receptors were characterized in rat uterus. The binding of [125I]ANP to uterine membranes was completely competed for by…”
Get more information