Search Results - "Muir, JL"

AMPA-induced excitotoxic lesions of the basal forebrain: a significant role for the cortical cholinergic system in attentional function by Muir, JL, Everitt, BJ, Robbins, TW

“…The aim of the present study was to clarify the role of the basal forebrain (BF)-cortical cholinergic system in visual attentional function by investigating…”
Get full text

The Role of the Nucleus Accumbens in Instrumental Conditioning: Evidence of a Functional Dissociation between Accumbens Core and Shell by Corbit, Laura H, Muir, Janice L, Balleine, Bernard W

“…In three experiments we examined the effect of bilateral excitotoxic lesions of the nucleus accumbens core or shell subregions on instrumental performance,…”
Get full text

Lesions of mediodorsal thalamus and anterior thalamic nuclei produce dissociable effects on instrumental conditioning in rats by Corbit, Laura H., Muir, Janice L., Balleine, Bernard W.

“…Two experiments examined the effects of bilateral excitotoxic lesions of either the mediodorsal (MD) or anterior (ANT) thalamic nuclei on instrumental…”
Get full text

Acetylcholine, Aging, and Alzheimer's Disease by Muir, Janice L

“…A substantial body of literature has suggested that the memory and learning deficits associated with Alzheimer's disease and aging are attributable to…”
Get full text

Functionally Dissociating Aspects of Event Memory: the Effects of Combined Perirhinal and Postrhinal Cortex Lesions on Object and Place Memory in the Rat by Bussey, Timothy J, Muir, Janice L, Aggleton, John P

“…Reciprocal interactions between the hippocampus and the perirhinal and parahippocampal cortices form core components of a proposed temporal lobe memory system…”
Get full text

The Cerebral Cortex of the Rat and Visual Attentional Function: Dissociable Effects of Mediofrontal, Cingulate, Anterior Dorsolateral, and Parietal Cortex Lesions on a Five-Choice Serial Reaction Time Task by Muir, Janice L., Everitt, Barry J., Robbins, Trevor W.

“…Dissociable effects of bilateral excitotoxic lesions of different regions of the rat neocortex, including medial prefrontal and anterior cingulate cortices,…”
Get full text

Frontal-striatal disconnection disrupts cognitive performance of the frontal-type in the rat by Dunnett, S.B., Meldrum, A., Muir, J.L.

“…The prefrontal cortex is considered to provide executive control of response selection and planning in diverse cognitive tasks, translated into action via…”
Get full text

The Conjoint Importance of the Hippocampus and Anterior Thalamic Nuclei for Allocentric Spatial Learning: Evidence from a Disconnection Study in the Rat by Warburton, E. Clea, Baird, Alison, Morgan, Angela, Muir, Janice L, Aggleton, John P

“…A disconnection procedure was used to test whether the hippocampus and anterior thalamic nuclei form functional components of the same spatial memory system…”
Get full text

Distinct patterns of behavioural impairments resulting from fornix transection or neurotoxic lesions of the perirhinal and postrhinal cortices in the rat by Bussey, Timothy J, Duck, Janette, Muir, Janice L, Aggleton, John P

“…The present study provides evidence that lesions of the fornix (FNX) and of the perirhinal/postrhinal cortex (PPRH), which both disconnect the hippocampus from…”
Get full text

Cyclical changes in endogenous levels of oestrogen modulate the induction of LTD and LTP in the hippocampal CA1 region by Good, Mark, Day, Mark, Muir, Janice L.

“…The present study investigated the effects of naturally fluctuating endogenous levels of oestrogen on the induction and maintenance of long‐term potentiation…”
Get full text

Visual Attention in the Rat: A Role for the Prelimbic Cortex and Thalamic Nuclei? by Chudasama, Yogita, Muir, Janice L

“…The behavioral effects of lesions of the prelimbic cortex (PL), mediodorsal nucleus of the thalamus (MD), and anterior thalamic nuclei (ANT) were investigated…”
Get full text

Effects of selective thalamic and prelimbic cortex lesions on two types of visual discrimination and reversal learning by Chudasama, Yogita, Bussey, Timothy J., Muir, Janice L.

“…The effects of excitotoxic lesions of the mediodorsal nucleus of the thalamus, the anterior thalamic nuclei and of the prelimbic cortex were examined on two…”
Get full text

Testing the importance of the caudal retrosplenial cortex for spatial memory in rats by Vann, Seralynne D, Kristina Wilton, L.A, Muir, Janice L, Aggleton, John P

“…Although there is evidence to suggest that the retrosplenial cortex is involved in spatial learning and memory, many lesion studies have left the more caudal…”
Get full text

Spatial shifts in visual attention in normal ageing and dementia of the Alzheimer type by Tales, Andrea, Muir, Janice L, Bayer, Anthony, Snowden, Robert J

“…Using a spatial-cueing paradigm, we assessed the ability of Alzheimer’s disease patients, age-matched controls and younger participants to use cues to guide…”
Get full text

A behavioural analysis of the delayed non-matching to position task : the effects of scopolamine, lesions of the fornix and of the prelimbic region on mediating behaviours by rats by CHUDASAMA, Y, MUIR, J. L

“…The delayed non-matching to position task (DNMP) is a widely used automated test of spatial memory, yet its validity has been challenged by suggestions that…”
Get full text

Triple Dissociation of Anterior Cingulate, Posterior Cingulate, and Medial Frontal Cortices on Visual Discrimination Tasks Using a Touchscreen Testing Procedure for the Rat by Bussey, Timothy J, Muir, Janice L, Everitt, Barry J, Robbins, Trevor W

“…Four experiments examined effects of quinolinic acid-induced lesions of the anterior cingulate, posterior cingulate, and medial frontal cortices on tests of…”
Get full text

6-Hydroxydopamine lesions of the prefrontal cortex in monkeys enhance performance on an analog of the Wisconsin Card Sort Test: possible interactions with subcortical dopamine by Roberts, AC, De Salvia, MA, Wilkinson, LS, Collins, P, Muir, JL, Everitt, BJ, Robbins, TW

“…The effects of 6-hydroxydopamine lesions of the prefrontal cortex in monkeys were investigated on two cognitive tests of prefrontal function, spatial delayed…”
Get full text

Disconnecting hippocampal projections to the anterior thalamus produces deficits on tests of spatial memory in rats by Warburton, E. C., Baird, A. L., Morgan, A., Muir, J. L., Aggleton, J. P.

“…A disconnection procedure was used to test whether projections from the hippocampus to the anterior thalamic nuclei (AT), via the fimbria‐fornix (FX), form…”
Get full text

Reversal of visual attentional dysfunction following lesions of the cholinergic basal forebrain by physostigmine and nicotine but not by the 5-HT3 receptor antagonist, ondansetron by MUIR, J. L, EVERITT, B. J, ROBBINS, T. W

“…To investigate further the cholinergic specificity of the effects of basal forebrain lesion-induced disruption of attentional performance, the present study…”
Get full text

Decline in visual attention and spatial memory in aged rats by Muir, J.L, Fischer, W, Björklund, A

“…The present study was a longitudinal study of age-related changes in performance of the 5-choice serial reaction time task, a test of visual attention…”
Get full text