Search Results - "Muijser, H"

Acute toxicity of high concentrations of carbon dioxide in rats by Muijser, H., van Triel, J.J., Duistermaat, E., Bos, P.M.J.

“…•Rats were exposed during a single 4h period to high concentrations of CO2.•Oxygen was not added to keep its concentration constant.•Mortality rate was fitted…”
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Neurobehavioral Effects of Cyclohexane in Rat and Human by Lammers, J. H. C. M., Emmen, H. H., Muijser, H., Hoogendijk, E. M. G., McKee, R. H., Owen, D. E., Kulig, B. M.

“…The neurobehavioral effects of inhaled cyclohexane in rats and humans are investigated to define relationships between internal doses and acute central nervous…”
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Neurobehavioral Effects of Acute Exposure to Isoparaffinic and Cycloparaffinic Hydrocarbons by McKee, Richard H., Lammers, J. H. C. M., Muijser, H., Owen, David E.

“…This article reports neurobehavioral tests in rats with C5-C11 isoparaffinic and cycloparaffinic hydrocarbons. Testing, conducted shortly after exposure,…”
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Neurobehavioral Effects of Acute Exposure to Aromatic Hydrocarbons by McKee, Richard H., Lammers, J. H. C. M., Muijser, H., Owen, D. E., Kulig, B. M.

“…This article reports the results of neurobehavioral tests on representative aromatic constituents, specifically C9 to C11 species. The testing evaluated…”
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Neurobehavioral Effects of Acute Exposure to Normal (n-) Paraffins by Lammers, J. H. C. M., Muijser, H., Owen, D. E., Kulig, B.M., McKee, R. H.

“…This article reports the results of neurobehavioral tests on C5-C10 normal paraffinic constituents (n-paraffins). Shortly after exposure, effects were…”
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Inhalation toxicity studies: OECD guidelines in relation to REACH and scientific developments by Arts, Josje H.E., Muijser, H., Jonker, D., van de Sandt, J.J.M., Bos, P.M.J., Feron, V.J.

“…The OECD Health Effects Test Guidelines (TGs) provide guidance concerning the use of methods for the identification and characterization of hazards from…”
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Physiologically Based Pharmacokinetic Modeling of Cyclohexane as a Tool for Integrating Animal and Human Test Data by Hissink, A. M., Kulig, B. M., Kruse, J., Freidig, A. P., Verwei, M., Muijser, H., Lammers, J. H. C. M., McKee, R. H., Owen, D. E., Sweeney, L. M., Salmon, F.

“…This report describes a physiologically based pharmacokinetic model for cyclohexane and its use in comparing internal doses in rats and volunteers following…”
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Model studies for evaluating the neurobehavioral effects of complex hydrocarbon solvents II. Neurobehavioral effects of white spirit in rat and human by LAMMERS, J. H. C. M, EMMEN, H. H, MUIJSER, H, HOOGENDIJK, E. M. G, MCKEE, R. H, OWEN, D. E, KULIG, B. M

“…To evaluate the neurobehavioral effects of hydrocarbon solvents and to establish a working model for extrapolating animal test data to humans, studies were…”
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Model studies for evaluating the neurobehavioral effects of complex hydrocarbon solvents III. PBPK modeling of white spirit constituents as a tool for integrating animal and human test data by HISSINK, A. M, KRÜSE, J, MCKEE, R. H, KULIG, B. M, VERWEI, M, MUIJSER, H, SALMON, F, LEENHEERS, L. H, OWEN, D. E, LAMMERS, J. H. C. M, FREIDIG, A. P

“…As part of a project designed to develop a framework for extrapolating acute central nervous system (CNS) effects of hydrocarbon solvents in animals to humans,…”
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Human Safety and Pharmacokinetics of the CFC Alternative Propellants HFC 134a (1,1,1,2-Tetrafluoroethane) and HFC 227 (1,1,1,2,3,3,3-Heptafluoropropane) Following Whole-Body Exposure by Emmen, H.H., Hoogendijk, E.M.G., Klöpping-Ketelaars, W.A.A., Muijser, H., Duistermaat, E., Ravensberg, J.C., Alexander, D.J., Borkhataria, D., Rusch, G.M., Schmit, B.

“…HFC 134a (1,1,1,2-tetrafluoroethane) and HFC 227 (1,1,1,2,3,3,3-heptafluoropropane) are used to replace chlorofluorocarbons (CFCs) in refrigerant and aerosol…”
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Human volunteer study with PGME: eye irritation during vapour exposure by Emmen, H.H, Muijser, H, Arts, J.H.E, Prinsen, M.K

“…The objective of this study was to establish the possible occurrence of eye irritation and subjective symptoms in human volunteers exposed to propylene glycol…”
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Model studies for evaluating the acute neurobehavioral effects of complex hydrocarbon solvents. I. Validation of methods with ethanol by MCKEE, R. H, LAMMERS, J. H. C. M, HOOGENDIJK, E. M. G, EMMEN, H. H, MUIJSER, H, BARSOTTI, D. A, OWEN, D. E, KULIG, B. M

“…As a preliminary step to evaluating the acute neurobehavioral effects of hydrocarbon solvents and to establish a working model for extrapolating animal test…”
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Model studies for evaluating the neurobehavioral effects of complex hydrocarbon solvents by Lammers, J.H.C.M., Emmen, H.H., Muijser, H., Hoogendijk, E.M.G., McKee, R.H., Owen, D.E., Kulig, B.M.

“…To evaluate the neurobehavioral effects of hydrocarbon solvents and to establish a working model for extrapolating animal test data to humans, studies were…”
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An indication for spatial integration in a non-Pacinian mechanoreceptor system? by Muijser, H

“…It is generally accepted that threshold sensitivity for cutaneous vibrational stimuli has a Pacinian component and a non-Pacinian component. While the Pacinian…”
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Model studies for evaluating the neurobehavioral effects of complex hydrocarbon solvents by Hissink, A.M., Krüse, J., Kulig, B.M., Verwei, M., Muijser, H., Salmon, F., Leenheers, L.H., Owen, D.E., Lammers, J.H.C.M., Freidig, A.P., McKee, R.H.

“…As part of a project designed to develop a framework for extrapolating acute central nervous system (CNS) effects of hydrocarbon solvents in animals to humans,…”
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A simple method for the calibration and equalization of whole-body startle measurements in the rat by Muijser, H

“…A dynamic calibration method for startle amplitude measurement systems for rats is described that is based on rotating weights. The calibration is dependent…”
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Model studies for evaluating the acute neurobehavioral effects of complex hydrocarbon solvents by McKee, R.H., Lammers, J.H.C.M., Hoogendijk, E.M.G., Emmen, H.H., Muijser, H., Barsotti, D.A., Owen, D.E., Kulig, B.M.

“…As a preliminary step to evaluating the acute neurobehavioral effects of hydrocarbon solvents and to establish a working model for extrapolating animal test…”
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Five-day inhalation toxicity study of three types of synthetic amorphous silicas in Wistar rats and post-exposure evaluations for up to 3 months by Arts, Josje H.E., Muijser, Hans, Duistermaat, Evert, Junker, Karin, Kuper, C. Frieke

“…Evidence suggests that short-term animal exposures to synthetic amorphous silicas (SAS) and crystalline silica can provide comparable prediction of toxicity to…”
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Short-Term Inhalation Exposure of Healthy and Compromised Rats and Mice to Fine and Ultrafine Carbon Particles by Arts, J.H.E., Spoor, S.M., Muijser, H., Kleinman, M.T., van Bree, L., Cassee, F.R.

“…Epidemiological studies have consistently shown associations between acute pulmonary effects and relatively low levels of ambient particulate matter (PM). The…”
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Effects of exposure to trichloroethylene and noise on hearing in rats by Muijser, H., Lammers, J. H.C.M., Kullig, B. M.

“…Four groups of rats (n=8 per group) were exposed to either 3000 ppm trichloroethylene (TCE) alone or to 95 dB SPL noise alone or to the combination of TCE and…”
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