Search Results - "Muhlethaler, Michel"

Elevated Tribbles homolog 2-specific antibody levels in narcolepsy patients by Cvetkovic-Lopes, Vesna, Bayer, Laurence, Dorsaz, Stéphane, Maret, Stéphanie, Pradervand, Sylvain, Dauvilliers, Yves, Lecendreux, Michel, Lammers, Gert-Jan, Donjacour, Claire E H M, Du Pasquier, Renaud A, Pfister, Corinne, Petit, Brice, Hor, Hyun, Mühlethaler, Michel, Tafti, Mehdi

“…Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness and attacks of muscle atonia triggered by strong emotions (cataplexy). Narcolepsy…”
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Effects of Hypocretin/Orexin and Major Transmitters of Arousal on Fast Spiking Neurons in Mouse Cortical Layer 6B by Wenger Combremont, Anne-Laure, Bayer, Laurence, Dupré, Anouk, Mühlethaler, Michel, Serafin, Mauro

“…Fast spiking (FS) GABAergic neurons are thought to be involved in the generation of high-frequency cortical rhythms during the waking state. We previously…”
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Slow Bursting Neurons of Mouse Cortical Layer 6b Are Depolarized by Hypocretin/Orexin and Major Transmitters of Arousal by Wenger Combremont, Anne-Laure, Bayer, Laurence, Dupré, Anouk, Mühlethaler, Michel, Serafin, Mauro

“…Neurons firing spontaneously in bursts in the absence of synaptic transmission have been previously recorded in different layers of cortical brain slices. It…”
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The Wake-Promoting Hypocretin/Orexin Neurons Change Their Response to Noradrenaline after Sleep Deprivation by Grivel, Jeremy, Cvetkovic, Vesna, Bayer, Laurence, Machard, Daniele, Tobler, Irene, Muhlethaler, Michel, Serafin, Mauro

“…Sleep deprivation is accompanied by the progressive development of an irresistible need to sleep, a phenomenon whose mechanism has remained elusive. Here, we…”
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Rocking Promotes Sleep in Mice through Rhythmic Stimulation of the Vestibular System by Kompotis, Konstantinos, Hubbard, Jeffrey, Emmenegger, Yann, Perrault, Aurore, Mühlethaler, Michel, Schwartz, Sophie, Bayer, Laurence, Franken, Paul

“…Rocking has long been known to promote sleep in infants and, more recently, also in adults, increasing NREM sleep stage N2 and enhancing EEG slow waves and…”
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Suprachiasmatic Modulation of Noradrenaline Release in the Ventrolateral Preoptic Nucleus by Saint-Mleux, Benoit, Bayer, Laurence, Eggermann, Emmanuel, Jones, Barbara E, Muhlethaler, Michel, Serafin, Mauro

“…As the major brain circadian pacemaker, the suprachiasmatic nucleus (SCN) is known to influence the timing of sleep and waking. We thus investigated here the…”
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Rocking synchronizes brain waves during a short nap by Bayer, Laurence, Constantinescu, Irina, Perrig, Stephen, Vienne, Julie, Vidal, Pierre-Paul, Mühlethaler, Michel, Schwartz, Sophie

“…Why do we cradle babies or irresistibly fall asleep in a hammock? Although such simple behaviors are common across cultures and generations, the nature of the…”
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Whole-Night Continuous Rocking Entrains Spontaneous Neural Oscillations with Benefits for Sleep and Memory by Perrault, Aurore A., Khani, Abbas, Quairiaux, Charles, Kompotis, Konstantinos, Franken, Paul, Muhlethaler, Michel, Schwartz, Sophie, Bayer, Laurence

“…Sensory processing continues during sleep and can influence brain oscillations. We previously showed that a gentle rocking stimulation (0.25 Hz), during an…”
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Exclusive Postsynaptic Action of Hypocretin-Orexin on Sublayer 6b Cortical Neurons by Bayer, Laurence, Serafin, Mauro, Eggermann, Emmanuel, Saint-Mleux, Benoit, Machard, Daniele, Jones, Barbara E, Muhlethaler, Michel

“…The hypocretin-orexin (hcrt-orx) neurons are thought to maintain wakefulness because their loss results in narcolepsy. This role may be fulfilled by the…”
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Distinct Contributions of High- and Low-Voltage-Activated Calcium Currents to Afterhyperpolarizations in Cholinergic Nucleus Basalis Neurons of the Guinea Pig by Williams, Sylvain, Serafin, Mauro, Muhlethaler, Michel, Bernheim, Laurent

“…The contributions made by low- (LVA) and high-voltage-activated (HVA) calcium currents to afterhyperpolarizations (AHPs) of nucleus basalis (NB) cholinergic…”
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Identification of sleep-promoting neurons in vitro by Mühlethaler, Michel, Gallopin, Thierry, Fort, Patrice, Eggermann, Emmanuel, Cauli, Bruno, Luppi, Pierre-Hervé, Rossier, Jean, Audinat, Etienne, Serafin, Mauro

“…The neurons responsible for the onset of sleep are thought to be located in the preoptic area and more specifically, in the ventrolateral preoptic nucleus…”
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The Wake-Promoting Hypocretin-Orexin Neurons Are in an Intrinsic State of Membrane Depolarization by Eggermann, Emmanuel, Bayer, Laurence, Serafin, Mauro, Saint-Mleux, Benoit, Bernheim, Laurent, Machard, Daniele, Jones, Barbara E, Muhlethaler, Michel

“…Wakefulness depends on the activity of hypocretin-orexin neurons because their lesion results in narcolepsy. How these neurons maintain their activity to…”
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Selective Action of Orexin (Hypocretin) on Nonspecific Thalamocortical Projection Neurons by Bayer, Laurence, Eggermann, Emmanuel, Saint-Mleux, Benoit, Machard, Daniele, Jones, Barbara E, Muhlethaler, Michel, Serafin, Mauro

“…As is evident from the pathological consequences of its absence in narcolepsy, orexin (hypocretin) appears to be critical for the maintenance of wakefulness…”
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Nicotinic Enhancement of the Noradrenergic Inhibition of Sleep-Promoting Neurons in the Ventrolateral Preoptic Area by Saint-Mleux, Benoit, Eggermann, Emmanuel, Bisetti, Arnaud, Bayer, Laurence, Machard, Daniele, Jones, Barbara E, Muhlethaler, Michel, Serafin, Mauro

“…According to multiple lines of evidence, neurons in the ventrolateral preoptic area (VLPO) that contain GABA promote sleep by inhibiting neurons of the arousal…”
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Orexins (hypocretins) directly excite tuberomammillary neurons by Bayer, Laurence, Eggermann, Emmanuel, Serafin, Mauro, Saint-Mleux, Benoît, Machard, D., Jones, Barbara, Mühlethaler, Michel

“…Wakefulness has recently been shown to depend upon the newly identified orexin (or hypocretin) neuropeptides by the findings that alteration in their precursor…”
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Rat hypocretin/orexin neurons are maintained in a depolarized state by TRPC channels by Cvetkovic-Lopes, Vesna, Eggermann, Emmanuel, Uschakov, Aaron, Grivel, Jeremy, Bayer, Laurence, Jones, Barbara E, Serafin, Mauro, Mühlethaler, Michel

“…In a previous study we proposed that the depolarized state of the wake-promoting hypocretin/orexin (hcrt/orx) neurons was independent of synaptic inputs as it…”
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The serotonin inhibition of high-voltage-activated calcium currents is relieved by action potential-like depolarizations in dissociated cholinergic nucleus basalis neurons of the guinea-pig by Williams, Sylvain, Serafin, Mauro, Mühlethaler, Michel, Bernheim, Laurent

“…The aim of the present study was to investigate whether the voltage‐dependent inhibition of calcium currents by serotonin 5‐HT1A agonists can be alleviated…”
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Sleep-deprivation regulates α-2 adrenergic responses of rat hypocretin/orexin neurons by Uschakov, Aaron, Grivel, Jeremy, Cvetkovic-Lopes, Vesna, Bayer, Laurence, Bernheim, Laurent, Jones, Barbara E, Mühlethaler, Michel, Serafin, Mauro

“…We recently demonstrated, in rat brain slices, that the usual excitation by noradrenaline (NA) of hypocretin/orexin (hcrt/orx) neurons was changed to an…”
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Oscillatory and Intrinsic Membrane Properties of Guinea Pig Nucleus Prepositus Hypoglossi Neurons In Vitro by Idoux, Erwin, Serafin, Mauro, Fort, Patrice, Vidal, Pierre-Paul, Beraneck, Mathieu, Vibert, Nicolas, Muhlethaler, Michel, Moore, L. E

“…1 Laboratoire de Neurobiologie des Réseaux Sensorimoteurs, Centre National de la Recherche Scientifique (CNRS)-Université René Descartes (Paris 5) Unité Mixte…”
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Facilitation of N-Type Calcium Current Is Dependent on the Frequency of Action Potential-Like Depolarizations in Dissociated Cholinergic Basal Forebrain Neurons of the Guinea Pig by Williams, Sylvain, Serafin, Mauro, Muhlethaler, Michel, Bernheim, Laurent

“…Voltage-dependent inhibition of high voltage-activated (HVA) calcium currents by G-proteins can be transiently relieved (facilitated) by strong depolarizing…”
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