Search Results - "Muhd Noor, Noor Dina"
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1
Probing the substrate binding modes and catalytic mechanisms of BLEG-1, a promiscuous B3 metallo-β-lactamase with glyoxalase II properties
Published in PloS one (06-09-2023)“…BLEG-1 from Bacillus lehensis G1 is an evolutionary divergent B3 metallo-β-lactamase (MBL) that exhibited both β-lactamase and glyoxalase II (GLXII)…”
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2
The Immobilization of Lipases on Porous Support by Adsorption and Hydrophobic Interaction Method
Published in Catalysts (01-07-2020)“…Four major enzymes commonly used in the market are lipases, proteases, amylases, and cellulases. For instance, in both academic and industrial levels,…”
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3
Versatility of subtilisin: A review on structure, characteristics, and applications
Published in Biotechnology and applied biochemistry (01-12-2022)“…Due to its thermostability and high pH compatibility, subtilisin is most known for its role as an additive for detergents in which it is categorized as a…”
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4
Dual Activity BLEG-1 from Bacillus lehensis G1 Revealed Structural Resemblance to B3 Metallo-β-Lactamase and Glyoxalase II: An Insight into Its Enzyme Promiscuity and Evolutionary Divergence
Published in International journal of molecular sciences (01-09-2021)“…Metallo-β-lactamases (MBLs) are class B β-lactamases from the metallo-hydrolase-like MBL-fold superfamily which act on a broad range of β-lactam antibiotics. A…”
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5
Opportunistic yeast pathogen Candida spp.: Secreted and membrane-bound virulence factors
Published in Medical mycology (Oxford) (03-12-2021)“…Abstract Candidiasis is a fungal infection caused by Candida spp. especially Candida albicans, C. glabrata, C. parapsilosis and C. tropicalis. Although the…”
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Bibliometric analysis and thematic review of Candida pathogenesis: Fundamental omics to applications as potential antifungal drugs and vaccines
Published in Medical mycology (Oxford) (09-01-2024)“…Invasive candidiasis caused by the pathogenic Candida yeast species has resulted in elevating global mortality. The pathogenicity of Candida spp. is not only…”
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7
Enolase in Meyerozyma guilliermondii strain SO: Sequential and structural insights of MgEno4581 as a putative virulence factor and host-fungal interactions through comprehensive in silico approaches
Published in Microbial pathogenesis (01-03-2023)“…Meyerozyma guilliermondii is a rare opportunistic fungal pathogen that causes deadly invasive candidiasis in human. M. guilliermondii strain SO is a local…”
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8
Identification and characterization of a promiscuous metallohydrolase in metallo-β-lactamase superfamily from a locally isolated organophosphate-degrading Bacillus sp. strain S3wahi
Published in International journal of biological macromolecules (01-06-2024)“…In this present study, characteristics and structure-function relationship of an organophosphate-degrading enzyme from Bacillus sp. S3wahi were described…”
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9
Main Structural Targets for Engineering Lipase Substrate Specificity
Published in Catalysts (01-07-2020)“…Microbial lipases represent one of the most important groups of biotechnological biocatalysts. However, the high-level production of lipases requires an…”
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10
Altering the Regioselectivity of T1 Lipase from Geobacillus zalihae toward sn-3 Acylglycerol Using a Rational Design Approach
Published in Catalysts (01-02-2023)“…The regioselectivity characteristic of lipases facilitate a wide range of novel molecule unit constructions and fat modifications. Lipases can be categorized…”
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11
Structure-Function and Industrial Relevance of Bacterial Aminopeptidase P
Published in Catalysts (01-10-2021)“…Aminopeptidase P (APPro, E.C 3.4.11.9) cleaves N-terminal amino acids from peptides and proteins where the penultimate residue is proline. This…”
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12
Structure Prediction of a Thermostable SR74 α-Amylase from Geobacillus stearothermophilus Expressed in CTG-Clade Yeast Meyerozyma guilliermondii Strain SO
Published in Catalysts (01-09-2020)“…α-amylase which catalyzes the hydrolysis of α-1,4-glycosidic bonds in starch have frequently been cloned into various microbial workhorses to yield a higher…”
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13
Effect of cysteine mutation at Ca2+ coordinating residues to the autolysis, folding and hydrophobicity of full length and mature Rand protease: molecular dynamics simulation and essential dynamics
Published in Journal of biomolecular structure & dynamics (21-11-2024)“…Rand protease is a serine protease that shared common characteristics with members of the MEROPS S8 subtilisin family. It is thermostable, highly stable in…”
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14
Procedure of the overexpression, purification and crystallization of BLEG-1, a bifunctional and evolutionary divergent B3 metallo-β-lactamase, for structure-function studies
Published in MethodsX (01-01-2022)“…Metallo-β-lactamases (MBLs) are class B β-lactamases from the metallo-hydrolase-like MBL-fold superfamily which act on a broad range of β-lactam antibiotics,…”
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15
Extracellular BSA-degrading SAPs in the rare pathogen Meyerozyma guilliermondii strain SO as potential virulence factors in candidiasis
Published in Microbial pathogenesis (01-08-2024)“…Meyerozyma guilliermondii (Candida guilliermondii) is one of the Candida species associated with invasive candidiasis. With the potential for expressing…”
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16
Effect of Ion Pair on Thermostability of F1 Protease: Integration of Computational and Experimental Approaches
Published in Journal of microbiology and biotechnology (01-01-2012)“…A thermophilic Bacillus stearothermophilus F1 produces an extremely thermostable serine protease. The F1 protease sequence was used to predict its…”
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17
Worldwide trend discovery of structural and functional relationship of metallo-β-lactamase for structure-based drug design: A bibliometric evaluation and patent analysis
Published in International journal of biological macromolecules (01-01-2024)“…Metallo-β-lactamase (MBL) is an enzyme produced by clinically important bacteria that can inactivate many commonly used antibiotics, making them a significant…”
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18
Exploring the Antarctic aminopeptidase P from Pseudomonas sp. strain AMS3 through structural analysis and molecular dynamics simulation
Published in Journal of biomolecular structure & dynamics (31-03-2024)“…Aminopeptidase P (APPro) is a crucial metalloaminopeptidase involved in amino acid cleavage from peptide N-termini, playing essential roles as versatile…”
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19
Effects of alcohol concentration and temperature on the dynamics and stability of mutant Staphylococcal lipase
Published in Journal of biomolecular structure & dynamics (15-11-2023)“…The stability and activity of lipase in organic media are important parameters in determining how quickly biocatalysis proceeds. This study aimed to examine…”
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20
Unraveling the crystal structure of Leptospira kmetyi riboflavin synthase and computational analyses for potential development of new antibacterials
Published in Journal of molecular structure (05-10-2022)“…•Leptospirosis is a bacterial disease that affects both humans and animals.•The 3D structure of a riboflavin synthase was determined by X-ray diffraction.•The…”
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