Search Results - "Muhammad Mahadi, Nor"
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Structure Flexibility of Alpha-galactosidase from a Marine Psychrophilic Yeast, Glaciozyma antarctica PI12
Published in Squalen (01-12-2022)“…Factors that contribute to maintaining the flexibility or stability of an enzyme structure may depend on the composition of each amino acid with different…”
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2
Danger lurking in the "unknowns": structure-to-function studies of hypothetical protein Bleg1_2437 from Bacillus lehensis G1 alkaliphile revealed an evolutionary divergent B3 metallo-beta-lactamase
Published in Journal of biochemistry (Tokyo) (01-02-2017)“…The effectiveness of β-lactam antibiotics as chemotherapeutic agents to treat bacterial infections is gradually threatened with the emergence of antibiotic…”
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3
effective extracellular protein secretion by an ABC transporter system in Escherichia coli: statistical modeling and optimization of cyclodextrin glucanotransferase secretory production
Published in Journal of industrial microbiology & biotechnology (01-09-2011)“…Direct transport of recombinant protein from cytosol to extracellular medium offers great advantages, such as high specific activity and a simple purification…”
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4
Optimisation of signal peptide for recombinant protein secretion in bacterial hosts
Published in Applied microbiology and biotechnology (01-05-2013)“…Escherichia coli —the powerhouse for recombinant protein production—is rapidly gaining status as a reliable and efficient host for secretory expression. An…”
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5
Expression of the Na⁺/H⁺ antiporter gene (g1-nhaC) of alkaliphilic Bacillus sp. G1 in Escherichia coli
Published in FEMS microbiology letters (01-11-2007)“…A Na⁺/H⁺ antiporter gene was isolated from alkaliphilic Bacillus sp. G1. The full-length sequence of the Na⁺/H⁺ antiporter gene was obtained using a genome…”
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6
The Glaciozyma antarctica genome reveals an array of systems that provide sustained responses towards temperature variations in a persistently cold habitat
Published in PloS one (31-01-2018)“…Extremely low temperatures present various challenges to life that include ice formation and effects on metabolic capacity. Psyhcrophilic microorganisms…”
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The characterisation of an alkali-stable maltogenic amylase from Bacillus lehensis G1 and improved malto-oligosaccharide production by hydrolysis suppression
Published in PloS one (15-09-2014)“…A maltogenic amylase (MAG1) from alkaliphilic Bacillus lehensis G1 was cloned, expressed in Escherichia coli, purified and characterised for its hydrolysis and…”
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8
Optimization of pretreatments for the hydrolysis of oil palm empty fruit bunch fiber (EFBF) using enzyme mixtures
Published in Biomass & bioenergy (01-09-2013)“…A study was conducted to optimize sugar production from oil palm empty fruit bunch fiber (EFBF). Three different pretreatments were applied to EFBF, namely…”
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Biochemical and structural characterization of a novel cold-active esterase-like protein from the psychrophilic yeast Glaciozyma antarctica
Published in Extremophiles : life under extreme conditions (01-07-2018)“…Dienelactone hydrolase, an α/β hydrolase enzyme, catalyzes the hydrolysis of dienelactone to maleylacetate, an intermediate for the Krebs cycle. Genome…”
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10
A Burkholderia pseudomallei Toxin Inhibits Helicase Activity of Translation Factor eIF4A
Published in Science (American Association for the Advancement of Science) (11-11-2011)“…The structure of BPSL1549, a protein of unknown function from Burkholderia pseudomallei, reveals a similarity to Escherichia coli cytotoxic necrotizing factor…”
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11
Emergence of the Asian lineage dengue virus type 3 genotype III in Malaysia
Published in BMC evolutionary biology (24-04-2018)“…Dengue virus type 3 genotype III (DENV3/III) is associated with increased number of severe infections when it emerged in the Americas and Asia. We had…”
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Dengue virus type 1 clade replacement in recurring homotypic outbreaks
Published in BMC evolutionary biology (28-09-2013)“…Recurring dengue outbreaks occur in cyclical pattern in most endemic countries. The recurrences of dengue virus (DENV) infection predispose the population to…”
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13
Structural and functional insights into TRiC chaperonin from a psychrophilic yeast, Glaciozyma antarctica
Published in Cell stress & chaperones (01-03-2019)“…Studies on TCP1-1 ring complex (TRiC) chaperonin have shown its indispensable role in folding cytosolic proteins in eukaryotes. In a psychrophilic organism,…”
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14
Characterization of Afp1, an antifreeze protein from the psychrophilic yeast Glaciozyma antarctica PI12
Published in Extremophiles : life under extreme conditions (01-01-2013)“…The psychrophilic yeast Glaciozyma antarctica demonstrated high antifreeze activity in its culture filtrate. The culture filtrate exhibited both thermal…”
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15
Characterization of Inducible HSP70 Genes in an Antarctic Yeast, Glaciozyma antarctica PI12, in Response to Thermal Stress
Published in Microorganisms (Basel) (30-09-2021)“…The induction of highly conserved heat shock protein 70 (HSP70) is often related to a cellular response due to harmful stress or adverse life conditions. In…”
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Structure Prediction of a Novel Exo-β-1,3-Glucanase: Insights into the Cold Adaptation of Psychrophilic Yeast Glaciozyma antarctica PI12
Published in Interdisciplinary sciences : computational life sciences (01-03-2018)“…We report a detailed structural analysis of the psychrophilic exo-β-1,3-glucanase (GaExg55) from Glaciozyma antarctica PI12. This study elucidates the…”
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17
Biochemical Characterisation and Structure Determination of a Novel Cold-Active Proline Iminopeptidase from the Psychrophilic Yeast, Glaciozyma antarctica PI12
Published in Catalysts (01-07-2022)“…Microbial proteases constitute one of the most important groups of industrially relevant enzymes. Proline iminopeptidases (PIPs) that specifically release…”
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Complete killing of Caenorhabditis elegans by Burkholderia pseudomallei is dependent on prolonged direct association with the viable pathogen
Published in PloS one (07-03-2011)“…Burkholderia pseudomallei is the causative agent of melioidosis, a disease of significant morbidity and mortality in both human and animals in endemic areas…”
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19
Biochemical Properties and Potential Application of Proteases from Alkalophilic Bacillus lehensis G1
Published in Tropical life sciences research (01-01-2019)“…The biochemical properties of extracellular proteases enzymes from Malaysia Alkalophilic’s bacteria, Bacillus lehensis G1, were investigated. The secreted…”
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Optimization of a heterologous signal peptide by site-directed mutagenesis for improved secretion of recombinant proteins in Escherichia coli
Published in Journal of molecular microbiology and biotechnology (01-01-2012)“…A heterologous signal peptide (SP) from Bacillus sp. G1 was optimized for secretion of recombinant cyclodextrin glucanotransferase (CGTase) to the periplasmic…”
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