Search Results - "Muha, Villő"

Uracil-containing DNA in Drosophila: stability, stage-specific accumulation, and developmental involvement by Muha, Villő, Horváth, András, Békési, Angéla, Pukáncsik, Mária, Hodoscsek, Barbara, Merényi, Gábor, Róna, Gergely, Batki, Júlia, Kiss, István, Jankovics, Ferenc, Vilmos, Péter, Erdélyi, Miklós, Vértessy, Beáta G

“…Base-excision repair and control of nucleotide pools safe-guard against permanent uracil accumulation in DNA relying on two key enzymes: uracil-DNA glycosylase…”
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A mouse model for functional dissection of TAB1 O-GlcNAcylation by Authier, Florence, Muha, Villő, van Aalten, Daan M.F.

“…Background: O-GlcNAcylation is a posttranslational modification associated with various physiological and pathophysiological processes including diabetes,…”
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Loss of O-GlcNAcase catalytic activity leads to defects in mouse embryogenesis by Muha, Villő, Authier, Florence, Szoke-Kovacs, Zsombor, Johnson, Sara, Gallagher, Jennifer, McNeilly, Alison, McCrimmon, Rory J., Teboul, Lydia, van Aalten, Daan M.F.

“…O-GlcNAcylation is an essential post-translational modification that has been implicated in neurodevelopmental and neurodegenerative disorders. O-GlcNAcase…”
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A novel fruitfly protein under developmental control degrades uracil-DNA by Békési, Angéla, Pukáncsik, Mária, Muha, Villő, Zagyva, Imre, Leveles, Ibolya, Hunyadi-Gulyás, Éva, Klement, Éva, Medzihradszky, Katalin F., Kele, Zoltán, Erdei, Anna, Felföldi, Ferenc, Kónya, Emese, Vértessy, Beáta G.

“…Uracil in DNA may arise by cytosine deamination or thymine replacement and is removed during DNA repair. Fruitfly larvae lack two repair enzymes, the major…”
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Intellectual disability-associated disruption of O-GlcNAc cycling impairs habituation learning in Drosophila by Fenckova, Michaela, Muha, Villo, Mariappa, Daniel, Catinozzi, Marica, Czajewski, Ignacy, Blok, Laura E R, Ferenbach, Andrew T, Storkebaum, Erik, Schenck, Annette, van Aalten, Daan M F

“…O-GlcNAcylation is a reversible co-/post-translational modification involved in a multitude of cellular processes. The addition and removal of the O-GlcNAc…”
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Functions and Mechanisms of Fibroblast Growth Factor (FGF) Signalling in Drosophila melanogaster by Muha, Villö, Müller, Hans-Arno J

“…Intercellular signalling via growth factors plays an important role in controlling cell differentiation and cell movements during the development of…”
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Loss of CRMP2 O-GlcNAcylation leads to reduced novel object recognition performance in mice by Muha, Villo, Williamson, Ritchie, Hills, Rachel, McNeilly, Alison D, McWilliams, Thomas G, Alonso, Jana, Schimpl, Marianne, Leney, Aneika C, Heck, Albert J R, Sutherland, Calum, Read, Kevin D, McCrimmon, Rory J, Brooks, Simon P, van Aalten, Daan M F

“…O-GlcNAcylation is an abundant post-translational modification in the nervous system, linked to both neurodevelopmental and neurodegenerative disease. However,…”
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Nuclear localization signal-dependent and -independent movements of Drosophila melanogaster dUTPase isoforms during nuclear cleavage by Muha, Villő, Zagyva, Imre, Venkei, Zsolt, Szabad, János, Vértessy, Beáta G.

“…Two dUTPase isoforms (23 kDa and 21 kDa) are present in the fruitfly with the sole difference of an N-terminal extension. In Drosophila embryo, both isoforms…”
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Expanding the DNA alphabet in the fruit fly: Uracil enrichment in genomic DNA by Horváth, András, Békési, Angéla, Muha, Villo, Erdélyi, Miklós, Vértessy, Beáta G.

“…DNA integrity is under the control of multiple pathways of nucleotide metabolism and DNA damage recognition and repair. Unusual sets of protein factors…”
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A mouse model for functional dissection of TAB1 O-GlcNAcylation by Authier, Florence, Muha, Villő, van Aalten, Daan M F

“…O-GlcNAcylation is a posttranslational modification associated with various physiological and pathophysiological processes including diabetes, cancer,…”
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O-GlcNAcase contributes to cognitive function in Drosophila by Muha, Villo, Fenckova, Michaela, Ferenbach, Andrew T., Catinozzi, Marica, Eidhof, Ilse, Storkebaum, Erik, Schenck, Annette, van Aalten, Daan M.F.

“…O-GlcNAcylation is an abundant post-translational modification in neurons. In mice, an increase in O-GlcNAcylation leads to defects in hippocampal synaptic…”
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Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability by Pravat, Veronica M., Muh, Villo, Gundogd, Mehmet, Ferenbac, Andrew T., Kakad, Poonam S., Vandad, Vasudha, Wilme, Ariane C., Borodki, Vladimir S., Jos, Shelagh, Stavridi, Marios P., van Aalten, Daan M. F.

“…O-GlcNAc transferase (OGT) is an X-linked gene product that is essential for normal development of the vertebrate embryo. It catalyses the O-GlcNAc…”
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Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability by Pravata, Veronica M, Muha, Villo, Gundogdu, Mehmet, Ferenbach, Andrew T, Kakade, Poonam S, Vandadi, Vasudha, Wilmes, Ariane C, Borodkin, Vladimir S, Joss, Shelagh, Stavridis, Marios P, van Aalten, Daan M F

“…Many bacteria contain cytoplasmic chemoreceptors that lack sensor domains. Here, we demonstrate that such cytoplasmic receptors found in 8 different bacterial…”
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Fibroblast growth factor signalling controls successive cell behaviours during mesoderm layer formation in Drosophila by Clark, Ivan B N, Muha, Villö, Klingseisen, Anna, Leptin, Maria, Müller, Hans-Arno J

“…Fibroblast growth factor (FGF)-dependent epithelial-mesenchymal transitions and cell migration contribute to the establishment of germ layers in vertebrates…”
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Association of RNA with the uracil-DNA-degrading factor has major conformational effects and is potentially involved in protein folding by Bekesi, Angela, Pukancsik, Maria, Haasz, Peter, Felfoldi, Lilla, Leveles, Ibolya, Muha, Villo, Hunyadi-Gulyas, Eva, Erdei, Anna, Medzihradszky, Katalin F, Vertessy, Beata G

“…Recently, a novel uracil-DNA-degrading factor protein (UDE) was identified in Drosophila melanogaster, with homologues only in pupating insects. Its unique…”
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