Search Results - "Mugyenyi, P"

Daily co-trimoxazole prophylaxis in severely immunosuppressed HIV-infected adults in Africa started on combination antiretroviral therapy: an observational analysis of the DART cohort by Walker, AS, Dr, Ford, D, PhD, Gilks, CF, Prof, Munderi, P, MBChB, Ssali, F, MBChB, Reid, A, MBChB, Katabira, E, Prof, Grosskurth, H, Prof, Mugyenyi, P, Prof, Hakim, J, Prof, Darbyshire, JH, Prof, Gibb, DM, Prof, Babiker, AG, Prof

“…Summary Background Co-trimoxazole prophylaxis can reduce mortality from untreated HIV infection in Africa; whether benefits occur alongside combination…”
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Long-term virological outcomes, failure and acquired resistance in a large cohort of Ugandan children by Huibers, M H W, Kityo, C, Boerma, R S, Kaudha, E, Sigaloff, K C E, Balinda, S N, Bertagnolio, S, Nakanjako, R, Mugyenyi, P, Calis, J C J, Boele van Hensbroek, M, Rinke de Wit, T F

“…Abstract Objectives To evaluate long-term virological failure (VF) and drug resistance among HIV-infected Ugandan children on first-line ART. Methods In a…”
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Adherence to HIV antiretroviral therapy in HIV+ Ugandan patients purchasing therapy by Byakika-Tusiime, J, Oyugi, J H, Tumwikirize, W A, Katabira, E T, Mugyenyi, P N, Bangsberg, D R

“…Our objective was to determine the level of adherence and reasons for non-adherence to antiretroviral therapy (ART) among HIV-positive (HIV+) people on ART in…”
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Cytochrome P450 2B6 (CYP2B6) G516T influences nevirapine plasma concentrations in HIV‐infected patients in Uganda by Penzak, SR, Kabuye, G, Mugyenyi, P, Mbamanya, F, Natarajan, V, Alfaro, RM, Kityo, C, Formentini, E, Masur, H

“…Objectives Polymorphisms in the cytochrome P450 (CYP) 2B6 gene have been shown to influence nevirapine plasma concentrations in HIV‐infected European…”
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A Randomized Trial of Punctuated Antiretroviral Therapy in Ugandan HIV-Seropositive Adults With Pulmonary Tuberculosis and CD4+ T-Cell Counts of ≥350 cells/μL by NANTEZA, M. W, MAYANJA-KIZZA, H, WHALEN, C. C, CHARLEBOIS, E, SRIKANTIAH, P, LIN, R, MUPERE, E, MUGYENYI, P, BOOM, W. H, MUGERWA, R. D, HAVLIR, D. V

“…Optimal treatment of human immunodeficiency virus (HIV)-associated tuberculosis in patients with high CD4⁺ T-cell counts is unknown. Suppression of viral…”
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P136 The clinical pattern, prevalence and factors associated with immune reconstitution inflammatory syndrome in children on HAART attending Joint Clinical Research Center by Orikiiriza, J, Kitaka, S, Mworozi, E, Mugyenyi, P

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Nevirapine/zidovudine/lamivudine has superior immunological and virological responses not reflected in clinical outcomes in a 48‐week randomized comparison with abacavir/zidovudine/lamivudine in HIV‐infected Ugandan adults with low CD4 cell counts by Munderi, P, Walker, AS, Kityo, C, Babiker, AG, Ssali, F, Reid, A, Darbyshire, JH, Grosskurth, H, Mugyenyi, P, Gibb, DM, Gilks, CF

“…Background Triple nucleoside reverse transcriptase inhibitor regimens have advantages as first‐line antiretroviral therapy (ART), avoiding hepatotoxicity and…”
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Impact of tuberculosis (TB) on HIV‐1 activity in dually infected patients by Toossi, Z., Mayanja‐Kizza, H., Hirsch, C. S., Edmonds, K. L., Spahlinger, T., Hom, D. L., Aung, H., Mugyenyi, P., Ellner, J. J., Whalen, C. W.

“…Active TB in HIV‐1‐infected subjects is associated with increased HIV‐1‐related immunodeficiency and mortality. We assessed plasma viral load in HIV‐1‐infected…”
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Achieving measles control: lessons from the 2002–06 measles control strategy for Uganda by Mbabazi, William B, Nanyunja, Miriam, Makumbi, Issa, Braka, Fiona, Baliraine, Frederick N, Kisakye, Annet, Bwogi, Josephine, Mugyenyi, Possy, Kabwongera, Eva, Lewis, Rosamund F

“…Background The 2002–06 measles control strategy for Uganda was implemented to strengthen routine immunization, undertake large-scale catch-up and follow-up…”
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Immunogenicity of a Recombinant Human Immunodeficiency Virus (HIV)–Canarypox Vaccine in HIV-Seronegative Ugandan Volunteers: Results of the HIV Network for Prevention Trials 007 Vaccine Study by Cao, H, Kaleebu, P, Hom, D, Flores, J, Agrawal, D, Jones, N, Serwanga, J, Okello, M, Walker, C, Sheppard, H, El-Habib, R, Klein, M, Mbidde, E, Mugyenyi, P, Walker, B, Ellner, J

“…In the first preventative human immunodeficiency virus (HIV) vaccine study to be carried out in Africa, 40 HIV-seronegative Ugandan volunteers were randomly…”
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Augmentation of Apoptosis and Interferon-γ Production at Sites of Active Mycobacterium tuberculosis Infection in Human Tuberculosis by Hirsch, C. S., Toossi, Z., Johnson, J. L., Luzze, H., Ntambi, L., Peters, P., McHugh, M., Okwera, A., Joloba, M., Mugyenyi, P., Mugerwa, R. D., Terebuh, P., Ellner, J. J.

“…Pleural tuberculosis (TB) was employed as a model to study T cell apoptosis at sites of active Mycobacterium tuberculosis (MTB) infection in human…”
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DART and laboratory monitoring of HIV treatment – Authors' reply by Walker, AS, Mugyenyi, P, Munderi, P, Gibb, DM, Gilks, CF

“…[...] programmes modelled on DART clinical monitoring will still need to build, staff, and equip laboratories to provide essential tests. [...] although the…”
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Introduction of an in-house PCR for routine identification of M. tuberculosis in a low-income country by MUHUMUZA, J, ASIIMWE, B. B, KAYES, S, MUGYENYI, P, WHALEN, C, MUGERWA, R. D, BOOM, H, EISENACH, K. D, JOLOBA, M. L

“…SETTING: National Tuberculosis (TB) Treatment Centre, Makerere University Medical School and Joint Clinical Research Centre, Kampala, Uganda.OBJECTIVE: To…”
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Sexual behaviour among persons living with HIV/AIDS in Kampala, Uganda by Tumukunde, D, Nuwaha, F, Ekirapa, E, Kityo, C, Ssali, F, Mugyenyi, P

“…To identify sexual behaviour and reproductive health needs of people living with HIV/AIDS (PLWHAs). A cross sectional study. Joint Clinical Research Centre,…”
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T cell activation, apoptosis and cytokine dysregulation in the (co)pathogenesis of HIV and pulmonary tuberculosis (TB) by Hertoghe, T, Wajja, A, Ntambi, L, Okwera, A, Aziz, M.A, Hirsch, C, Johnson, J, Toossi, Z, Mugerwa, R, Mugyenyi, P, Colebunders, R, Ellner, J, Vanham, G

“…Immune parameters were compared in four groups of Ugandan subjects: HIV⁻and HIV⁺ adult patients with active pulmonary TB (HIV⁻ PTB n = 38; HIV⁺ PTB n = 28),…”
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Duration of efficacy of treatment of latent tuberculosis infection in HIV-infected adults by JOHNSON, John L, OKWERA, Alphonse, VERNON, Andrew, MUGERWA, Roy D, ELLNER, Jerrold J, WHALEN, Christopher C, HOM, David L, MAYANJA, Harriet, CISSY MUTULUUZA KITYO, NSUBUGA, Peter, NAKIBALI, Joseph G, LOUGHLIN, Anita M, HYUN YUN, MUGYENYI, Peter N

“…Treatment of latent infection is needed to protect HIV-infected individuals against tuberculosis. A previous report addressed short-term efficacy of three…”
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Decreased Serum Opsonic Activity against Streptococcus pneumoniae in Human Immunodeficiency Virus—Infected Ugandan Adults by Takahashi, Hidehiko, Oishi, Kazunori, Yoshimine, Hiroyuki, Kumatori, Atsushi, Moji, Kazuhiko, Watanabe, Kiwao, Nalwoga, Hawa, Tugume, Sitefano Buguruka, Kebba, Anthony, Mugerwa, Roy, Mugyenyi, Peter, Nagatake, Tsuyoshi

“…Type-specific immunoglobulin G (IgG) to pneumococcal capsular polysaccharide (CPS) and opsonic activity against Streptococcus pneumoniae were evaluated in…”
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HIV vaccines: the Uganda experience by Mugyenyi, Peter N

“…By late 1980s Uganda was the epicenter of the AIDS epidemic in the world but strong preventive interventions and committed leadership has turned the epidemic…”
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Widow inheritance and HIV/AIDS in rural Uganda by Mabumba, E D, Mugyenyi, P, Batwala, V, Mulogo, E M, Mirembe, J, Khan, F A, Liljestrand, J

“…Despite current efforts to combat HIV/AIDS through behavioural change, ingrained socio-cultural practices such as widow inheritance in south-western Uganda has…”
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Enhanced Prophylaxis plus Antiretroviral Therapy for Advanced HIV Infection in Africa by Hakim, James, Musiime, Victor, Szubert, Alex J, Mallewa, Jane, Siika, Abraham, Agutu, Clara, Walker, Simon, Pett, Sarah L, Bwakura-Dangarembizi, Mutsa, Lugemwa, Abbas, Kaunda, Symon, Karoney, Mercy, Musoro, Godfrey, Kabahenda, Sheila, Nathoo, Kusum, Maitland, Kathryn, Griffiths, Anna, Thomason, Margaret J, Kityo, Cissy, Mugyenyi, Peter, Prendergast, Andrew J, Walker, A. Sarah, Gibb, Diana M

“…High mortality is associated with initiation of antiretroviral therapy for HIV. In this report from sub-Saharan Africa, enhanced prophylaxis with isoniazid,…”
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