Search Results - "Mughal, T I"

Biology and clinical management of myeloproliferative neoplasms and development of the JAK inhibitor ruxolitinib by Mascarenhas, J, Mughal, T I, Verstovsek, S

“…Myeloproliferative neoplasms (MPN) are debilitating stem cell-derived clonal myeloid malignancies. Conventional treatments for the BCR-ABL1-negative MPN…”
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Myeloproliferative neoplasms and inflammation: whether to target the malignant clone or the inflammatory process or both by Koschmieder, S, Mughal, T I, Hasselbalch, H C, Barosi, G, Valent, P, Kiladjian, J-J, Jeryczynski, G, Gisslinger, H, Jutzi, J S, Pahl, H L, Hehlmann, R, Maria Vannucchi, A, Cervantes, F, Silver, R T, Barbui, T

“…The Philadelphia-negative myeloproliferative neoplasms (MPNs) are clonal disorders involving hematopoietic stem and progenitor cells and are associated with…”
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Patterns of Outcome and Prognostic Factors in Primary Large-Cell Lymphoma of the Testis in a Survey by the International Extranodal Lymphoma Study Group by ZUCCA, E, CONCONI, A, CORTELAZZO, S, FERRERI, A. J. M, AMBROSETTI, A, MARTELLI, M, THIEBLEMONT, C, GOMEZ MORENO, H, PINOTTI, G, MARTINELLI, G, MOZZANA, R, GRISANTI, S, MUGHAL, T. I, PROVENCIO, M, BALZAROTTI, M, LAVEDER, F, OLTEAN, G, CALLED, V, ROY, P, CAVALLI, F, GOSPODAROWICZ, M. K, SARRIS, A. H, SEYMOUR, J. F, VITOLO, U, KLASA, R, OZSAHIN, M, MEAD, G. M, GIANNI, M. A

“…To determine clinical features and patterns of outcome of primary testicular diffuse large B-cell lymphomas (DLCL). A retrospective international survey of 373…”
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Hybrid capture-based genomic profiling of circulating tumor DNA from patients with estrogen receptor-positive metastatic breast cancer by Chung, J.H., Pavlick, D., Hartmaier, R., Schrock, A.B., Young, L., Forcier, B., Ye, P., Levin, M.K., Goldberg, M., Burris, H., Gay, L.M., Hoffman, A.D., Stephens, P.J., Frampton, G.M., Lipson, D.M., Nguyen, D.M., Ganesan, S., Park, B.H., Vahdat, L.T., Leyland-Jones, B., Mughal, T.I., Pusztai, L., O’Shaughnessy, J., Miller, V.A., Ross, J.S., Ali, S.M.

“…Genomic changes that occur in breast cancer during the course of disease have been informed by sequencing of primary and metastatic tumor tissue. For patients…”
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Chronic myeloid leukaemia: STI 571 magnifies the therapeutic dilemma by Mughal, T.I., Goldman, J.M.

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Novel PDGFRB fusions in childhood B- and T-acute lymphoblastic leukemia by Heilmann, A M, Schrock, A B, He, J, Nahas, M, Curran, K, Shukla, N, Cramer, S, Draper, L, Verma, A, Erlich, R, Ross, J, Stephens, P, Miller, V A, Ali, S M, Verglio, J-A, Tallman, M S, Mughal, T I

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Comprehensive profiling and molecularly guided therapy (MGT) for carcinomas of unknown primary (CUP): CUPISCO: A phase II, randomised, multicentre study comparing targeted therapy or immunotherapy with standard platinum-based chemotherapy by Krämer, A, Losa, F, Gay, L M, Page, D R, Foser, S, Mughal, T I, Ross, J S, Baciarello, G, Mileshkin, L R, Osborne, S, Moch, H

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Bi-allelic inactivation is more prevalent at relapse in multiple myeloma, identifying RB1 as an independent prognostic marker by Chavan, S S, He, J, Tytarenko, R, Deshpande, S, Patel, P, Bailey, M, Stein, C K, Stephens, O, Weinhold, N, Petty, N, Steward, D, Rasche, L, Bauer, M, Ashby, C, Peterson, E, Ali, S, Ross, J, Miller, V A, Stephens, P, Thanendrarajan, S, Schinke, C, Zangari, M, van Rhee, F, Barlogie, B, Mughal, T I, Davies, F E, Morgan, G J, Walker, B A

“…The purpose of this study is to identify prognostic markers and treatment targets using a clinically certified sequencing panel in multiple myeloma. We…”
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P529: FIRST EUROPEAN REAL‐WORLD EVIDENCE PROSPECTIVE REGISTRY OF FIRST‐LINE ADULT PATIENTS WITH BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM TREATED WITH FIRST‐IN‐CLASS CD123‐TARGETED THERAPY TAGRAXOFUSP by Platzbecker, U., Angelucci, E., Montesinos, P., Lemoli, R. M., Spyridonidis, A., Casariego, J., Mughal, T. I., Mohty, M.

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Allo-SCT for myelofibrosis: reversing the chronic phase in the JAK inhibitor era? by Tamari, R, Mughal, T I, Rondelli, D, Hasserjian, R, Gupta, V, Odenike, O, Fauble, V, Finazzi, G, Pane, F, Mascarenhas, J, Prchal, J, Giralt, S, Hoffman, R

“…At present, allo-SCT is the only curative treatment for patients with myelofibrosis (MF). Unfortunately, a significant proportion of candidate patients are…”
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P521: TREATMENT OF BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM IN PEDIATRIC PATIENTS WITH TAGRAXOFUSP, A CD123‐TARGETED THERAPY by Pemmaraju, N., Cuglievan, B., Lasky, J., Kheradpour, A., Hijiya, N., Stein, A. S., Meshinchi, S., Mullen, C., Angelucci, E., Vinti, L., Mughal, T. I., Pawlowska, A.

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Chronic myeloid leukaemia: a therapeutic challenge by Mughal, T I, Goldman, J M

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Treatment of metastatic malignant melanoma with recombinant interferon alpha 2 by Robinson, W A, Mughal, T I, Thomas, M R, Johnson, M, Spiegel, R J

“…Fifty-nine patients with metastatic malignant melanoma were entered into a phase II trial of recombinant alpha-2 interferon given in a dosage of 10 million…”
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Role of interferon alfa-2b in the management of patients with advanced cutaneous T-cell lymphoma by Mughal, T I

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A pilot study of interferon alpha and 5-fluorouracil in hepatocellular carcinoma by Mughal, T I, Koriech, O M

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Molecular studies in patients with chronic myeloid leukaemia in remission 5 years after allogeneic stem cell transplant define the risk of subsequent relapse by Mughal, Tariq I., Yong, Agnes, Szydlo, Richard M., Dazzi, Francesco, Olavarria, Eduardo, Van Rhee, Frits, Kaeda, Jaspal, Cross, Nick C. P., Craddock, Charles, Kanfer, Ed, Apperley, Jane, Goldman, John M.

“…We identified 103 consecutive patients who, 5 years after allogeneic transplantation for chronic myeloid leukaemia (CML), were in molecular remission (MR). The…”
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An integrated approach to the management of chronic myeloid leukemia by Mughal, T I, Goldman, J M

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Chronic myeloid leukemia: reminiscences and dreams by Mughal, Tariq I, Radich, Jerald P, Deininger, Michael W, Apperley, Jane F, Hughes, Timothy P, Harrison, Christine J, Gambacorti-Passerini, Carlo, Saglio, Giuseppe, Cortes, Jorge, Daley, George Q

“…With the deaths of Janet Rowley and John Goldman in December 2013, the world lost two pioneers in the field of chronic myeloid leukemia. In 1973, Janet Rowley,…”
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An International MDS/MPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplastic/myeloproliferative neoplasms by Mughal, Tariq I, Cross, Nicholas C P, Padron, Eric, Tiu, Ramon V, Savona, Michael, Malcovati, Luca, Tibes, Raoul, Komrokji, Rami S, Kiladjian, Jean-Jacques, Garcia-Manero, Guillermo, Orazi, Attilio, Mesa, Ruben, Maciejewski, Jaroslaw P, Fenaux, Pierre, Itzykson, Raphael, Mufti, Ghulam, Solary, Eric, List, Alan F

“…In the 2008 WHO classification, chronic myeloid malignancies that share both myelodysplastic and myeloproliferative features define the…”
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Role of recombinant alpha-interferon in the treatment of advanced cutaneous malignant melanoma by Mughal, T I, Thomas, M R, Robinson, W A

“…A total of 65 patients with advanced cutaneous malignant melanoma (MM) have now been treated with interferon alpha-2b (Intron A) at a dose of 10 million IU/m2…”
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